These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

264 related articles for article (PubMed ID: 8220911)

  • 1. Human liver microsomal metabolism of the enantiomers of warfarin and acenocoumarol: P450 isozyme diversity determines the differences in their pharmacokinetics.
    Hermans JJ; Thijssen HH
    Br J Pharmacol; 1993 Sep; 110(1):482-90. PubMed ID: 8220911
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Comparison of the rat liver microsomal metabolism of the enantiomers of warfarin and 4'-nitrowarfarin (acenocoumarol).
    Hermans JJ; Thijssen HH
    Xenobiotica; 1991 Mar; 21(3):295-307. PubMed ID: 1862655
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cytochrome P4502C9 is the principal catalyst of racemic acenocoumarol hydroxylation reactions in human liver microsomes.
    Thijssen HH; Flinois JP; Beaune PH
    Drug Metab Dispos; 2000 Nov; 28(11):1284-90. PubMed ID: 11038154
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effect of omeprazole on the hydroxylation of warfarin enantiomers in human: in-vitro studies with liver microsomes and cDNA-expressed cytochrome P450 isozymes.
    Zhou Q; Zhou S; Chan E
    Curr Drug Metab; 2005 Oct; 6(5):399-411. PubMed ID: 16248835
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of cytochrome P450 2C9 and an allelic variant in the 4'-hydroxylation of (R)- and (S)-flurbiprofen.
    Tracy TS; Rosenbluth BW; Wrighton SA; Gonzalez FJ; Korzekwa KR
    Biochem Pharmacol; 1995 May; 49(9):1269-75. PubMed ID: 7763308
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of human CYP isoforms involved in the metabolism of propranolol enantiomers--N-desisopropylation is mediated mainly by CYP1A2.
    Yoshimoto K; Echizen H; Chiba K; Tani M; Ishizaki T
    Br J Clin Pharmacol; 1995 Apr; 39(4):421-31. PubMed ID: 7640150
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Formation of (R)-8-hydroxywarfarin in human liver microsomes. A new metabolic marker for the (S)-mephenytoin hydroxylase, P4502C19.
    Wienkers LC; Wurden CJ; Storch E; Kunze KL; Rettie AE; Trager WF
    Drug Metab Dispos; 1996 May; 24(5):610-4. PubMed ID: 8723744
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nature of cytochromes P450 involved in the 2-/4-hydroxylations of estradiol in human liver microsomes.
    Kerlan V; Dreano Y; Bercovici JP; Beaune PH; Floch HH; Berthou F
    Biochem Pharmacol; 1992 Nov; 44(9):1745-56. PubMed ID: 1449532
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enantiomer/enantiomer interaction of (S)- and (R)-propafenone for cytochrome P450IID6-catalyzed 5-hydroxylation: in vitro evaluation of the mechanism.
    Kroemer HK; Fischer C; Meese CO; Eichelbaum M
    Mol Pharmacol; 1991 Jul; 40(1):135-42. PubMed ID: 1857335
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human liver cytochrome P450 enzymes involved in the 7-hydroxylation of R- and S-warfarin enantiomers.
    Yamazaki H; Shimada T
    Biochem Pharmacol; 1997 Dec; 54(11):1195-203. PubMed ID: 9416970
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Monkey liver cytochrome P450 2C19 is involved in R- and S-warfarin 7-hydroxylation.
    Hosoi Y; Uno Y; Murayama N; Fujino H; Shukuya M; Iwasaki K; Shimizu M; Utoh M; Yamazaki H
    Biochem Pharmacol; 2012 Dec; 84(12):1691-5. PubMed ID: 23041648
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human and mouse liver coumarin 7-hydroxylases do not metabolize warfarin in vitro.
    Honkakoski P; Arvela P; Juvonen R; Lang MA; Kairaluoma M; Pelkonen O
    Br J Clin Pharmacol; 1992 Mar; 33(3):313-7. PubMed ID: 1576054
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regioselective and stereoselective metabolism of ibuprofen by human cytochrome P450 2C.
    Hamman MA; Thompson GA; Hall SD
    Biochem Pharmacol; 1997 Jul; 54(1):33-41. PubMed ID: 9296349
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Stereoselective inhibition of cytochrome P450 forms by lansoprazole and omeprazole in vitro.
    Liu KH; Kim MJ; Shon JH; Moon YS; Seol SY; Kang W; Cha IJ; Shin JG
    Xenobiotica; 2005 Jan; 35(1):27-38. PubMed ID: 15788366
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of CYP2C19 and CYP2C9 from human liver: respective roles in microsomal tolbutamide, S-mephenytoin, and omeprazole hydroxylations.
    Lasker JM; Wester MR; Aramsombatdee E; Raucy JL
    Arch Biochem Biophys; 1998 May; 353(1):16-28. PubMed ID: 9578596
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Metabolic enantiomeric interactions: the inhibition of human (S)-warfarin-7-hydroxylase by (R)-warfarin.
    Kunze KL; Eddy AC; Gibaldi M; Trager WF
    Chirality; 1991; 3(1):24-9. PubMed ID: 2039681
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human hepatic cytochrome P-450 composition as probed by in vitro microsomal metabolism of warfarin.
    Kaminsky LS; Dunbar DA; Wang PP; Beaune P; Larrey D; Guengerich FP; Schnellmann RG; Sipes IG
    Drug Metab Dispos; 1984; 12(4):470-7. PubMed ID: 6148215
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions.
    Rettie AE; Korzekwa KR; Kunze KL; Lawrence RF; Eddy AC; Aoyama T; Gelboin HV; Gonzalez FJ; Trager WF
    Chem Res Toxicol; 1992; 5(1):54-9. PubMed ID: 1581537
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Influence of Amlodipine Enantiomers on Human Microsomal Cytochromes P450: Stereoselective Time-Dependent Inhibition of CYP3A Enzyme Activity.
    Krasulova K; Holas O; Anzenbacher P
    Molecules; 2017 Nov; 22(11):. PubMed ID: 29099769
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cytochrome P-450 isozyme/isozyme functional interactions and NADPH-cytochrome P-450 reductase concentrations as factors in microsomal metabolism of warfarin.
    Kaminsky LS; Guengerich FP
    Eur J Biochem; 1985 Jun; 149(3):479-89. PubMed ID: 3924614
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.