BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 8221635)

  • 1. Studies on the mutagenic activation of heterocyclic amines by cynomolgus monkey, rat and human microsomes show that cynomolgus monkeys have a low capacity to N-oxidize the quinoxaline-type heterocyclic amines.
    Davis CD; Adamson RH; Snyderwine EG
    Cancer Lett; 1993 Sep; 73(2-3):95-104. PubMed ID: 8221635
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cytochromes P450 in cynomolgus monkeys mutagenically activate 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) but not 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx).
    Sadrieh N; Snyderwine EG
    Carcinogenesis; 1995 Jul; 16(7):1549-55. PubMed ID: 7614688
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutagenic activation of IQ, PhIP and MeIQx by hepatic microsomes from rat, monkey and man: low mutagenic activation of MeIQx in cynomolgus monkeys in vitro reflects low DNA adduct levels in vivo.
    Davis CD; Schut HA; Adamson RH; Thorgeirsson UP; Thorgeirsson SS; Snyderwine EG
    Carcinogenesis; 1993 Jan; 14(1):61-5. PubMed ID: 8425272
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Contribution of CYP1A1 and CYP1A2 to the activation of heterocyclic amines in monkeys and human.
    Edwards RJ; Murray BP; Murray S; Schulz T; Neubert D; Gant TW; Thorgeirsson SS; Boobis AR; Davies DS
    Carcinogenesis; 1994 May; 15(5):829-36. PubMed ID: 8200083
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon.
    Turesky RJ; Lang NP; Butler MA; Teitel CH; Kadlubar FF
    Carcinogenesis; 1991 Oct; 12(10):1839-45. PubMed ID: 1934265
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation and effects of the food-derived heterocyclic amines in extrahepatic tissues.
    Overvik E; Hellmold H; Branting C; Gustafsson JA
    Princess Takamatsu Symp; 1995; 23():123-33. PubMed ID: 8844803
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metabolic activation and genotoxicity of heterocyclic arylamines.
    Snyderwine EG; Schut HA; Adamson RH; Thorgeirsson UP; Thorgeirsson SS
    Cancer Res; 1992 Apr; 52(7 Suppl):2099s-2102s. PubMed ID: 1544147
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cytochrome P450 forms in the rodent lung involved in the metabolic activation of food-derived heterocyclic amines.
    Hellmold H; Overvik E; Strömstedt M; Gustafsson JA
    Carcinogenesis; 1993 Sep; 14(9):1751-7. PubMed ID: 8403195
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Metabolic processing and disposition of 2-amino-3-methylimidazo[4,5-f] quinoline (IQ), 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in nonhuman primates.
    Snyderwine EG; Turesky RJ; Buonarati MH; Turteltaub KW; Adamson RH
    Princess Takamatsu Symp; 1995; 23():69-77. PubMed ID: 8844797
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Metabolic processing and carcinogenicity of heterocyclic amines in nonhuman primates.
    Adamson RH; Snyderwine EG; Thorgeirsson UP; Schut HA; Turesky RJ; Thorgeirsson SS; Takayama S; Sugimura T
    Princess Takamatsu Symp; 1990; 21():289-301. PubMed ID: 2134682
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Exposure to and activation of dietary heterocyclic amines in humans.
    Lynch AM; Murray S; Gooderham NJ; Boobis AR
    Crit Rev Oncol Hematol; 1995 Nov; 21(1-3):19-31. PubMed ID: 8822495
    [No Abstract]   [Full Text] [Related]  

  • 12. Metabolic activation of heterocyclic amine food mutagens in the mammary gland of lactating Fischer 344 rats.
    Davis CD; Ghoshal A; Schut HA; Snyderwine EG
    Cancer Lett; 1994 Aug; 84(1):67-73. PubMed ID: 7915639
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Possible relationship between tissue distribution of DNA adducts and genotoxicity of food-derived heterocyclic amines.
    Thorgeirsson SS; Davis CD; Schut HA; Adamson RH; Snyderwine EG
    Princess Takamatsu Symp; 1995; 23():85-92. PubMed ID: 8844799
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Heterocyclic aromatic amines induce DNA strand breaks and cell transformation.
    Pfau W; Martin FL; Cole KJ; Venitt S; Phillips DH; Grover PL; Marquardt H
    Carcinogenesis; 1999 Apr; 20(4):545-51. PubMed ID: 10223180
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Enzymatic studies of the activation of heterocyclic food mutagens in man.
    Boobis AR; Gooderham NJ; Rich KJ; Zhao K; Edwards RJ; Murray BP; Lynch AM; Murray S; Davies DS
    Princess Takamatsu Symp; 1995; 23():134-44. PubMed ID: 8844804
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dietary heterocyclic amines as potential human carcinogens: experimental data from nonhuman primates.
    Thorgeirsson UP; Snyderwine EG; Gomez DE; Adamson RH
    In Vivo; 1996; 10(2):145-52. PubMed ID: 8744793
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interspecies homology of cytochrome P-450: toxicological significance of cytochrome P-450 cross-reactive with anti-rat P-448-H antibodies in liver microsomes from dogs, monkeys and humans.
    Ohta K; Kitada M; Ohi H; Komori M; Nagashima K; Sato N; Muroya K; Kodama T; Nagao M; Kamataki T
    Mutat Res; 1989 Jul; 226(3):163-7. PubMed ID: 2501680
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effects of cigarette smoke and a heterocyclic amine, MeIQx on cytochrome P-450, mutagenic activation of various carcinogens and glucuronidation in rat liver.
    Mori Y; Koide A; Kobayashi Y; Furukawa F; Hirose M; Nishikawa A
    Mutagenesis; 2003 Jan; 18(1):87-93. PubMed ID: 12473741
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of heterocyclic aromatic amines by rat and human liver microsomes and by purified rat and human cytochrome P450 1A2.
    Turesky RJ; Constable A; Richoz J; Varga N; Markovic J; Martin MV; Guengerich FP
    Chem Res Toxicol; 1998 Aug; 11(8):925-36. PubMed ID: 9705755
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutagenicity of some synthetic quinolines and quinoxalines related to IQ, MeIQ or MeIQx in Ames test.
    Grivas S; Jägerstad M
    Mutat Res; 1984 Jul; 137(1):29-32. PubMed ID: 6379435
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.