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2. Novel diazinone derivatives separate myofilament Ca2+ sensitization and phosphodiesterase III inhibitory effects in guinea pig myocardium. Ventura C; Miller R; Wolf HP; Beier N; Jonas R; Klockow M; Lues I; Hano O; Spurgeon HA; Lakatta EG Circ Res; 1992 Jun; 70(6):1081-90. PubMed ID: 1533576 [TBL] [Abstract][Full Text] [Related]
3. CGP-48506 increases contractility of ventricular myocytes and myofilaments by effects on actin-myosin reaction. Wolska BM; Kitada Y; Palmiter KA; Westfall MV; Johnson MD; Solaro RJ Am J Physiol; 1996 Jan; 270(1 Pt 2):H24-32. PubMed ID: 8769730 [TBL] [Abstract][Full Text] [Related]
4. The two mechanisms of action of racemic cardiotonic EMD 53998, calcium sensitization and phosphodiesterase inhibition, reside in different enantiomers. Lues I; Beier N; Jonas R; Klockow M; Haeusler G J Cardiovasc Pharmacol; 1993 Jun; 21(6):883-92. PubMed ID: 7687712 [TBL] [Abstract][Full Text] [Related]
5. Ca2+ sensitization in idiopathic dilated human myocardium. Differential in vitro effects of (+)-(5-methyl-6-phenyl)-1,3,5,6-tetrahydro-3,6-methano-1,5-benzodiazoci ne-2,4-dione, a novel purely Ca2+sensitizing agent, and (+)-5-(1-(3,4-dimethoxybenzoyl)-1,2,3,4-tetrahydroquinolin-6-yl)-6-meth yl-3, 6-dihydro-2H-1,3,4-thiadiazin-2-one on skinned fibres and isolated ventricular strips. Herzig JW; Chiesi M; Depersin H; GrĂ¼ninger S; Hasenfuss G; Kubalek R; Leutert T; Pieske B; Pioch K; Wenk P; Holubarsch C Arzneimittelforschung; 1996 Jun; 46(6):586-93. PubMed ID: 8767348 [TBL] [Abstract][Full Text] [Related]
6. A novel positive inotropic substance enhances contractility without increasing the Ca2+ transient in rat myocardium. Ferroni C; Hano O; Ventura C; Lakatta EG; Klockow M; Spurgeon H; Capogrossi MC J Mol Cell Cardiol; 1991 Mar; 23(3):325-31. PubMed ID: 1880816 [TBL] [Abstract][Full Text] [Related]
7. Enantiomeric dissection of the effects of the inotropic agent, EMD 53998, in single cardiac myocytes. Gambassi G; Capogrossi MC; Klockow M; Lakatta EG Am J Physiol; 1993 Mar; 264(3 Pt 2):H728-38. PubMed ID: 8384421 [TBL] [Abstract][Full Text] [Related]
8. The effects of EMD 57033 on rigor tension in porcine skinned cardiac trabecula. Palmer S; Di Bello S; Herzig JW Eur J Pharmacol; 1995 Dec; 294(1):83-90. PubMed ID: 8788419 [TBL] [Abstract][Full Text] [Related]
9. The thiadiazinone EMD 57033 speeds the activation of skinned cardiac muscle produced by the photolysis of nitr-5. Simnett SJ; Lipscomb S; Ashley CC; Potter JD; Mulligan IP Pflugers Arch; 1994 Jul; 427(5-6):550-2. PubMed ID: 7971154 [TBL] [Abstract][Full Text] [Related]
10. The effect of a thiadiazinone derived Ca2+ sensitizer on the responsiveness of Mg(2+)-ATPase to Ca2+ in myofibrils isolated from stunned and nonstunned porcine and human myocardium. Bezstarosti K; Soei LK; Krams R; Ten Cate FJ; Verdouw PD; Lamers JM Biochem Pharmacol; 1996 May; 51(9):1211-20. PubMed ID: 8645345 [TBL] [Abstract][Full Text] [Related]
11. (-)-Enantiomer EMD 57439 antagonizes the Ca2+ sensitizing effect of (+)-enantiomer EMD 57033 on diastolic function but not on systolic function in rabbit ventricular cardiomyocytes. Sugawara H; Endoh M Jpn J Pharmacol; 1999 May; 80(1):55-65. PubMed ID: 10446757 [TBL] [Abstract][Full Text] [Related]
12. In vivo evidence of positive inotropism of EMD 57033 through calcium sensitization. Haeusler G; Jonas R; Minck KO; Schliep HJ; Schelling P; Weygandt H; Lues I J Cardiovasc Pharmacol; 1997 May; 29(5):647-55. PubMed ID: 9213208 [TBL] [Abstract][Full Text] [Related]
13. The Ca2+ sensitizer EMD 53998 antagonizes the effect of 2,3-butanedione monoxime on skinned cardiac muscle fibres. Barth Z; Strauss JD; Dohet C; Ruegg JC Eur J Pharmacol; 1996 Feb; 296(3):285-9. PubMed ID: 8904080 [TBL] [Abstract][Full Text] [Related]
14. The novel cardiotonic agent EMD 53 998 is a potent "calcium sensitizer". Beier N; Harting J; Jonas R; Klockow M; Lues I; Haeusler G J Cardiovasc Pharmacol; 1991 Jul; 18(1):17-27. PubMed ID: 1719287 [TBL] [Abstract][Full Text] [Related]
15. Sensitization of dog and guinea pig heart myofilaments to Ca2+ activation and the inotropic effect of pimobendan: comparison with milrinone. Fujino K; Sperelakis N; Solaro RJ Circ Res; 1988 Nov; 63(5):911-22. PubMed ID: 2846200 [TBL] [Abstract][Full Text] [Related]
16. Differential effects of the optical isomers of EMD 53998 on contraction and cytoplasmic Ca2+ in isolated ferret cardiac muscle. White J; Lee JA; Shah N; Orchard CH Circ Res; 1993 Jul; 73(1):61-70. PubMed ID: 8508534 [TBL] [Abstract][Full Text] [Related]
17. In vivo evidence that EMD 57033 restores myocardial responsiveness to intracoronary Ca(2+) in stunned myocardium. de Zeeuw S; Trines SA; Krams R; Duncker DJ; Verdouw PD Eur J Pharmacol; 2000 Sep; 403(1-2):99-109. PubMed ID: 10969150 [TBL] [Abstract][Full Text] [Related]
18. Attenuation of length dependence of calcium activation in myofilaments of transgenic mouse hearts expressing slow skeletal troponin I. Arteaga GM; Palmiter KA; Leiden JM; Solaro RJ J Physiol; 2000 Aug; 526 Pt 3(Pt 3):541-9. PubMed ID: 10922006 [TBL] [Abstract][Full Text] [Related]
19. E-1020, a water soluble imidazopyridine, has direct effects on Ca(2+)-dependent force and ATP hydrolysis of canine and bovine cardiac myofilaments. Powers FM; Palmiter KA; Solaro RJ Mol Cell Biochem; 1996; 160-161():33-9. PubMed ID: 8901452 [TBL] [Abstract][Full Text] [Related]
20. Different chronotropic and inotropic effects of EMD 57033 and EMD 53998, Ca2+ sensitizers, on isolated, blood-perfused dog heart preparations. Lakhe M; Furukawa Y; Yonezawa T; Hirose M; Nagashima Y; Miyashita Y; Chiba S Jpn J Pharmacol; 1998 Apr; 76(4):435-9. PubMed ID: 9623723 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]