BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

179 related articles for article (PubMed ID: 8230124)

  • 1. Synthesis of paraxanthine analogs (1,7-disubstituted xanthines) and other xanthines unsubstituted at the 3-position: structure-activity relationships at adenosine receptors.
    Müller CE; Shi D; Manning M; Daly JW
    J Med Chem; 1993 Oct; 36(22):3341-9. PubMed ID: 8230124
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-activity relationships in a series of 8-substituted xanthines as A1-adenosine receptor antagonists.
    Strappaghetti G; Corsano S; Barbaro R; Giannaccini G; Betti L
    Bioorg Med Chem; 2001 Mar; 9(3):575-83. PubMed ID: 11310591
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 8-Azaxanthine derivatives as antagonists of adenosine receptors.
    Franchetti P; Messini L; Cappellacci L; Grifantini M; Lucacchini A; Martini C; Senatore G
    J Med Chem; 1994 Sep; 37(18):2970-5. PubMed ID: 8071944
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and structure-activity relationships of deazaxanthines: analogs of potent A1- and A2-adenosine receptor antagonists.
    Grahner B; Winiwarter S; Lanzner W; Müller CE
    J Med Chem; 1994 May; 37(10):1526-34. PubMed ID: 8182711
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors.
    Jacobson KA; Shi D; Gallo-Rodriguez C; Manning M; Müller C; Daly JW; Neumeyer JL; Kiriasis L; Pfleiderer W
    J Med Chem; 1993 Sep; 36(18):2639-44. PubMed ID: 8410976
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of substituent size upon adenosine receptor A1/A2 affinity of some newly synthesised 8-cycloalkyl xanthines.
    Castagnino E; Salvatori A; Corsano S; Tacchi P; Martini C; Lucacchini A
    Drug Des Discov; 1995 Apr; 12(4):313-21. PubMed ID: 9040991
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions.
    Kim SA; Marshall MA; Melman N; Kim HS; Müller CE; Linden J; Jacobson KA
    J Med Chem; 2002 May; 45(11):2131-8. PubMed ID: 12014951
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel 1,3-disubstituted 8-(1-benzyl-1H-pyrazol-4-yl) xanthines: high affinity and selective A2B adenosine receptor antagonists.
    Kalla RV; Elzein E; Perry T; Li X; Palle V; Varkhedkar V; Gimbel A; Maa T; Zeng D; Zablocki J
    J Med Chem; 2006 Jun; 49(12):3682-92. PubMed ID: 16759111
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chronic effects of xanthines on levels of central receptors in mice.
    Shi D; Daly JW
    Cell Mol Neurobiol; 1999 Dec; 19(6):719-32. PubMed ID: 10456233
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 125I-labeled 8-phenylxanthine derivatives: antagonist radioligands for adenosine A1 receptors.
    Linden J; Patel A; Earl CQ; Craig RH; Daluge SM
    J Med Chem; 1988 Apr; 31(4):745-51. PubMed ID: 3351850
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 1,3,8-trisubstituted xanthines. Effects of substitution pattern upon adenosine receptor A1/A2 affinity.
    Erickson RH; Hiner RN; Feeney SW; Blake PR; Rzeszotarski WJ; Hicks RP; Costello DG; Abreu ME
    J Med Chem; 1991 Apr; 34(4):1431-5. PubMed ID: 2016719
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Thermodynamics of full agonist, partial agonist, and antagonist binding to wild-type and mutant adenosine A1 receptors.
    Dalpiaz A; Townsend-Nicholson A; Beukers MW; Schofield PR; IJzerman AP
    Biochem Pharmacol; 1998 Dec; 56(11):1437-45. PubMed ID: 9827575
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure-activity relationships of 8-styrylxanthines as A2-selective adenosine antagonists.
    Jacobson KA; Gallo-Rodriguez C; Melman N; Fischer B; Maillard M; van Bergen A; van Galen PJ; Karton Y
    J Med Chem; 1993 May; 36(10):1333-42. PubMed ID: 8496902
    [TBL] [Abstract][Full Text] [Related]  

  • 14. De novo analysis of receptor binding affinity data of xanthine adenosine receptor antagonists.
    Dalpiaz A; Gardenghi A; Borea PA
    Arzneimittelforschung; 1995 Mar; 45(3):230-3. PubMed ID: 7741774
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and pharmacological evaluation of novel 1,3,8- and 1,3,7,8-substituted xanthines as adenosine receptor antagonists.
    Rodríguez-Borges JE; García-Mera X; Balo MC; Brea J; Caamaño O; Fernández F; López C; Loza MI; Nieto MI
    Bioorg Med Chem; 2010 Mar; 18(5):2001-9. PubMed ID: 20137957
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure-activity relationships of 1,3-dialkylxanthine derivatives at rat A3 adenosine receptors.
    Kim HO; Ji XD; Melman N; Olah ME; Stiles GL; Jacobson KA
    J Med Chem; 1994 Sep; 37(20):3373-82. PubMed ID: 7932565
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Analogues of caffeine and theophylline: effect of structural alterations on affinity at adenosine receptors.
    Daly JW; Padgett WL; Shamim MT
    J Med Chem; 1986 Jul; 29(7):1305-8. PubMed ID: 3806581
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Xanthines with C8 chiral substituents as potent and selective adenosine A1 antagonists.
    Peet NP; Lentz NL; Dudley MW; Ogden AM; McCarty DR; Racke MM
    J Med Chem; 1993 Dec; 36(25):4015-20. PubMed ID: 8258823
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sulfur-containing 1,3-dialkylxanthine derivatives as selective antagonists at A1-adenosine receptors.
    Jacobson KA; Kiriasis L; Barone S; Bradbury BJ; Kammula U; Campagne JM; Secunda S; Daly JW; Neumeyer JL; Pfleiderer W
    J Med Chem; 1989 Aug; 32(8):1873-9. PubMed ID: 2754711
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and pharmacological evaluation of novel 1- and 8-substituted-3-furfuryl xanthines as adenosine receptor antagonists.
    Balo MC; Brea J; Caamaño O; Fernández F; García-Mera X; López C; Loza MI; Nieto MI; Rodríguez-Borges JE
    Bioorg Med Chem; 2009 Sep; 17(18):6755-60. PubMed ID: 19682912
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.