120 related articles for article (PubMed ID: 8230137)
1. 9-[(Phosphonoalkyl)benzyl]guanines. Multisubstrate analogue inhibitors of human erythrocyte purine nucleoside phosphorylase.
Kelley JL; Linn JA; McLean EW; Tuttle JV
J Med Chem; 1993 Oct; 36(22):3455-63. PubMed ID: 8230137
[TBL] [Abstract][Full Text] [Related]
2. [[(Guaninylalkyl)phosphinico]methyl]phosphonic acids. Multisubstrate analogue inhibitors of human erythrocyte purine nucleoside phosphorylase.
Kelley JL; McLean EW; Crouch RC; Averett DR; Tuttle JV
J Med Chem; 1995 Mar; 38(6):1005-14. PubMed ID: 7699692
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and evaluation of multisubstrate analogue inhibitors of purine nucleoside phosphorylases.
Yokomatsu T; Hayakawa Y; Kihara T; Koyanagi S; Soeda S; Shimeno H; Shibuya S
Bioorg Med Chem; 2000 Nov; 8(11):2571-9. PubMed ID: 11092542
[TBL] [Abstract][Full Text] [Related]
4. 8-Amino-9-substituted guanines: potent purine nucleoside phosphorylase (PNP) inhibitors.
Sircar JC; Kostlan CR; Pinter GW; Suto MJ; Bobovski TP; Capiris T; Schwender CF; Dong MK; Scott ME; Bennett MK
Agents Actions; 1987 Aug; 21(3-4):253-6. PubMed ID: 3120506
[TBL] [Abstract][Full Text] [Related]
5. Guanine, pyrazolo[3,4-d]pyrimidine, and triazolo[4,5-d]pyrimidine (8-azaguanine) phosphonate acyclic derivatives as inhibitors of purine nucleoside phosphorylase.
Beauchamp LM; Tuttle JV; Rodriguez ME; Sznaidman ML
J Med Chem; 1996 Feb; 39(4):949-56. PubMed ID: 8632418
[TBL] [Abstract][Full Text] [Related]
6. Antiproliferative activity of purine nucleoside phosphorylase multisubstrate analogue inhibitors containing difluoromethylene phosphonic acid against leukaemia and lymphoma cells.
Glavas-Obrovac L; Suver M; Hikishima S; Hashimoto M; Yokomatsu T; Magnowska L; Bzowska A
Chem Biol Drug Des; 2010 Apr; 75(4):392-9. PubMed ID: 20102369
[TBL] [Abstract][Full Text] [Related]
7. Calf spleen purine-nucleoside phosphorylase: crystal structure of the binary complex with a potent multisubstrate analogue inhibitor.
Luić M; Koellner G; Yokomatsu T; Shibuya S; Bzowska A
Acta Crystallogr D Biol Crystallogr; 2004 Aug; 60(Pt 8):1417-24. PubMed ID: 15272165
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis, and enzymatic evaluation of multisubstrate analogue inhibitors of Escherichia coli thymidine phosphorylase.
Esteban-Gamboa A; Balzarini J; Esnouf R; De Clercq E; Camarasa MJ; Pérez-Pérez MJ
J Med Chem; 2000 Mar; 43(5):971-83. PubMed ID: 10715161
[TBL] [Abstract][Full Text] [Related]
9. Potentiation of 2'-deoxyguanosine cytotoxicity by a novel inhibitor of purine nucleoside phosphorylase, 8-amino-9-benzylguanine.
Shewach DS; Chern JW; Pillote KE; Townsend LB; Daddona PE
Cancer Res; 1986 Feb; 46(2):519-23. PubMed ID: 3079664
[TBL] [Abstract][Full Text] [Related]
10. Purine nucleoside phosphorylase inhibitors: biochemical and pharmacological studies with 9-benzyl-9-deazaguanine and related compounds.
Bennett LL; Allan PW; Noker PE; Rose LM; Niwas S; Montgomery JA; Erion MD
J Pharmacol Exp Ther; 1993 Aug; 266(2):707-14. PubMed ID: 8355201
[TBL] [Abstract][Full Text] [Related]
11. Novel multisubstrate inhibitors of mammalian purine nucleoside phosphorylase.
Toms AV; Wang W; Li Y; Ganem B; Ealick SE
Acta Crystallogr D Biol Crystallogr; 2005 Nov; 61(Pt 11):1449-58. PubMed ID: 16239721
[TBL] [Abstract][Full Text] [Related]
12. Acyclonucleoside analogue inhibitors of mammalian purine nucleoside phosphorylase.
Bzowska A; Kulikowska E; Shugar D; Chen BY; Lindborg B; Johansson NG
Biochem Pharmacol; 1991 Jun; 41(12):1791-803. PubMed ID: 1903945
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and biological evaluation of 1,1-difluoro-2-(tetrahydro-3-furanyl)ethylphosphonic acids possessing a N9-purinylmethyl functional group at the ring. a new class of inhibitors for purine nucleoside phosphorylases.
Yokomatsu T; Hayakawa Y; Suemune K; Kihara T; Soeda S; Shimeno H; Shibuya S
Bioorg Med Chem Lett; 1999 Oct; 9(19):2833-6. PubMed ID: 10522701
[TBL] [Abstract][Full Text] [Related]
14. The biochemical and pharmacological activity of 9-benzyl-9-deazaguanine, a potent purine nucleoside phosphorylase (PNP) inhibitor.
Kimble E; Hadala J; Ludewig R; Peters P; Greenberg G; Xiao G; Guida W; McQuire L; Simon P
Inflamm Res; 1995 Aug; 44 Suppl 2():S181-2. PubMed ID: 8548387
[No Abstract] [Full Text] [Related]
15. Kinetics of binding of multisubstrate analogue inhibitor (2-amino-9-[2-(phosphonomethoxy)ethyl]-6-sulfanylpurine) with trimeric purine nucleoside phosphorylase.
Antosiewicz J; Wielgus-Kutrowska B; Długosz M; Holy A; Bzowska A
Nucleosides Nucleotides Nucleic Acids; 2007; 26(8-9):969-74. PubMed ID: 18058519
[TBL] [Abstract][Full Text] [Related]
16. One-third-the-sites transition-state inhibitors for purine nucleoside phosphorylase.
Miles RW; Tyler PC; Furneaux RH; Bagdassarian CK; Schramm VL
Biochemistry; 1998 Jun; 37(24):8615-21. PubMed ID: 9628722
[TBL] [Abstract][Full Text] [Related]
17. Structural-based design and synthesis of novel 9-deazaguanine derivatives having a phosphate mimic as multi-substrate analogue inhibitors for mammalian PNPs.
Hikishima S; Hashimoto M; Magnowska L; Bzowska A; Yokomatsu T
Bioorg Med Chem; 2010 Mar; 18(6):2275-2284. PubMed ID: 20189401
[TBL] [Abstract][Full Text] [Related]
18. Rational design of quinazoline-based irreversible inhibitors of human erythrocyte purine nucleoside phosphorylase.
Dempcy RO; Skibo EB
Biochemistry; 1991 Aug; 30(34):8480-7. PubMed ID: 1909177
[TBL] [Abstract][Full Text] [Related]
19. Antiviral acyclic nucleoside phosphonate analogues as inhibitors of purine nucleoside phosphorylase.
Kulikowska E; Bzowska A; Holy A; Magnowska L; Shugar D
Adv Exp Med Biol; 1998; 431():747-52. PubMed ID: 9598163
[No Abstract] [Full Text] [Related]
20. Pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase (PNP) inhibitors as potential T-cell selective immunosuppressive agents.
Sircar JC; Kostlan CR; Gilbertsen RB; Dong MK; Cetenko WA
Adv Exp Med Biol; 1991; 309A():45-8. PubMed ID: 1789265
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]