BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 8233777)

  • 1. The synthesis of oligoribonucleotides containing O6-methylguanosine: the role of conserved guanosine residues in hammerhead ribozyme cleavage.
    Grasby JA; Jonathan P; Butler G; Gait MJ
    Nucleic Acids Res; 1993 Sep; 21(19):4444-50. PubMed ID: 8233777
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Importance of exocyclic base functional groups of central core guanosines for hammerhead ribozyme activity.
    Tuschl T; Ng MM; Pieken W; Benseler F; Eckstein F
    Biochemistry; 1993 Nov; 32(43):11658-68. PubMed ID: 8218233
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The roles of the conserved pyrimidine bases in hammerhead ribozyme catalysis: evidence for a magnesium ion-binding site.
    Murray JB; Adams CJ; Arnold JR; Stockley PG
    Biochem J; 1995 Oct; 311 ( Pt 2)(Pt 2):487-94. PubMed ID: 7487885
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Model for general acid-base catalysis by the hammerhead ribozyme: pH-activity relationships of G8 and G12 variants at the putative active site.
    Han J; Burke JM
    Biochemistry; 2005 May; 44(21):7864-70. PubMed ID: 15910000
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural variation induced by different nucleotides at the cleavage site of the hammerhead ribozyme.
    Simorre JP; Legault P; Baidya N; Uhlenbeck OC; Maloney L; Wincott F; Usman N; Beigelman L; Pardi A
    Biochemistry; 1998 Mar; 37(12):4034-44. PubMed ID: 9521724
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Three conserved guanosines approach the reaction site in native and minimal hammerhead ribozymes.
    Lambert D; Heckman JE; Burke JM
    Biochemistry; 2006 Jun; 45(23):7140-7. PubMed ID: 16752904
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sequence specificity of the hammerhead ribozyme revisited; the NHH rule.
    Kore AR; Vaish NK; Kutzke U; Eckstein F
    Nucleic Acids Res; 1998 Sep; 26(18):4116-20. PubMed ID: 9722629
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of phosphorothioate and 2-amino groups in hammerhead ribozymes on cleavage rates and Mg2+ binding.
    Koizumi M; Ohtsuka E
    Biochemistry; 1991 May; 30(21):5145-50. PubMed ID: 2036380
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nuclease resistant hammerhead motif: from '5-ribo' to '3-ribo' model.
    Matulic-Adamic J; Daniher AT; Gonzalez C; Beigelman L
    Bioorg Med Chem Lett; 1999 Jan; 9(2):157-60. PubMed ID: 10021919
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A kinetic and thermodynamic analysis of cleavage site mutations in the hammerhead ribozyme.
    Baidya N; Uhlenbeck OC
    Biochemistry; 1997 Feb; 36(5):1108-14. PubMed ID: 9033401
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Purine functional groups in essential residues of the hairpin ribozyme required for catalytic cleavage of RNA.
    Grasby JA; Mersmann K; Singh M; Gait MJ
    Biochemistry; 1995 Mar; 34(12):4068-76. PubMed ID: 7535099
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rapid desilylation of oligoribonucleotides at elevated temperatures: cleavage activity in ribozyme-substrate assays.
    Vinayak R; Andrus A; Hampel A
    Biomed Pept Proteins Nucleic Acids; 1995; 1(4):227-30. PubMed ID: 9346836
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Function of specific 2'-hydroxyl groups of guanosines in a hammerhead ribozyme probed by 2' modifications.
    Williams DM; Pieken WA; Eckstein F
    Proc Natl Acad Sci U S A; 1992 Feb; 89(3):918-21. PubMed ID: 1736306
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Configurationally defined phosphorothioate-containing oligoribonucleotides in the study of the mechanism of cleavage of hammerhead ribozymes.
    Slim G; Gait MJ
    Nucleic Acids Res; 1991 Mar; 19(6):1183-8. PubMed ID: 1709484
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis of site-specifically modified oligoribonucleotides for studies of the recognition of TAR RNA by HIV-1 tat protein and studies of hammerhead ribozymes.
    Slim G; Pritchard C; Biala E; Asseline U; Gait MJ
    Nucleic Acids Symp Ser; 1991; (24):55-8. PubMed ID: 1841380
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Importance of specific guanosine N7-nitrogens and purine amino groups for efficient cleavage by a hammerhead ribozyme.
    Fu DJ; Rajur SB; McLaughlin LW
    Biochemistry; 1993 Oct; 32(40):10629-37. PubMed ID: 8399208
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural and catalytic effects of an invariant purine substitution in the hammerhead ribozyme: implications for the mechanism of acid-base catalysis.
    Schultz EP; Vasquez EE; Scott WG
    Acta Crystallogr D Biol Crystallogr; 2014 Sep; 70(Pt 9):2256-63. PubMed ID: 25195740
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Construction of new ribozymes requiring short regulator oligonucleotides as a cofactor.
    Komatsu Y; Yamashita S; Kazama N; Nobuoka K; Ohtsuka E
    J Mol Biol; 2000 Jun; 299(5):1231-43. PubMed ID: 10873448
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and NMR study of ribo-oligonucleotides forming a hammerhead-type RNA enzyme system.
    Odai O; Kodama H; Hiroaki H; Sakata T; Tanaka T; Uesugi S
    Nucleic Acids Res; 1990 Oct; 18(20):5955-60. PubMed ID: 1700365
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-function studies of the hammerhead ribozyme.
    Verma S; Vaish NK; Eckstein F
    Curr Opin Chem Biol; 1997 Dec; 1(4):532-6. PubMed ID: 9667883
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.