BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 8240250)

  • 1. Modification of 1 alpha,25-dihydroxyvitamin D3 metabolism by introduction of 26,26,26,27,27,27-hexafluoro atoms in human promyelocytic leukaemia (HL-60) cells: isolation and identification of a novel bioactive metabolite, 26,26,26,27,27,27-hexafluoro-1 alpha,23(S),25-trihydroxyvitamin D3.
    Honda A; Nakashima N; Shida Y; Mori Y; Nagata A; Ishizuka S
    Biochem J; 1993 Oct; 295 ( Pt 2)(Pt 2):509-16. PubMed ID: 8240250
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolism of 26,27-hexafluoro-1 alpha,25-dihydroxyvitamin D3 and 26,27-hexafluoro-1 alpha,23(S)25-trihydroxyvitamin D3 in ROS17/2.8 cells transfected with a plasmid expressing CYP24.
    Miyahara T; Gomyo S; Ueda Y; Ohyama Y; Sigeno C; Kozakai A; Takamura T; Yamazaki R; Higuchi S; Yamamoto M; Sakuma T; Nemoto N
    Xenobiotica; 2000 Nov; 30(11):1055-62. PubMed ID: 11197067
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effects of vitamin D-binding proteins on HL-60 cell differentiation induced by 26,26,26,27,27,27-hexafluoro-1 alpha,25-dihydroxyvitamin D.
    Honda A; Nakashima N; Mori Y; Katsumata T; Ishizuka S
    J Steroid Biochem Mol Biol; 1992 Jan; 41(1):109-12. PubMed ID: 1310414
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effect of substituting fluorine for hydrogen at C-26 and C-27 on the side chain of 1,25-dihydroxyvitamin D3.
    Inaba M; Okuno S; Nishizawa Y; Imanishi Y; Katsumata T; Sugata I; Morii H
    Biochem Pharmacol; 1993 Jun; 45(11):2331-6. PubMed ID: 8517874
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comparison of 26,27-hexafluoro-1 alpha,25-dihydroxyvitamin D3 and 1 alpha,25-dihydroxyvitamin D3 on the resorption of bone explants ex vivo.
    Miyahara T; Harada M; Kozakai A; Matsumoto M; Hashimoto K; Inoue H; Yoda K; Nakatsu T; Kajita S; Yamazaki R; Higuchi S; Kozuka H; Nemoto N
    J Nutr Sci Vitaminol (Tokyo); 1999 Jun; 45(3):239-49. PubMed ID: 10524344
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects on cultured neonatal mouse calvaria of 1 alpha,25-dihydroxyvitamin D3, 26,26,26,27,27,27-hexafluoro-1 alpha,25-dihydroxyvitamin D3 and 26,26,26,27,27,27-hexafluoro-1 alpha,23S,25-trihydroxyvitamin D3.
    Harada M; Miyahara T; Miyata M; Tomita I; Okayachi H; Ikemoto Y; Higuchi S; Otomo S; Kozuka H; Ikekawa N
    Bone Miner; 1992 Jul; 18(1):41-9. PubMed ID: 1422297
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effect of a highly potent fluoro analog of 1,25-dihydroxyvitamin D3 on human bone-derived cells.
    Kiriyama T; Okamoto S; Ejima E; Kurihara N; Hakeda Y; Ito N; Izumi M; Kumegawa M; Nagataki S
    Endocrinology; 1991 Jan; 128(1):81-6. PubMed ID: 1846118
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Biological activities of 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 on human promyelocytic leukemic HL-60 cells: effects of fetal bovine serum and of incubation time.
    Okuno S; Inaba M; Nishizawa Y; Morii H
    Miner Electrolyte Metab; 1995; 21(1-3):211-6. PubMed ID: 7565452
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differences in metabolism between 26,26,26,27,27,27-hexafluoro-1 alpha, 25-dihydroxyvitamin D3 and 1 alpha, 25-dihydroxyvitamin D3 in cultured neonatal mouse calvaria.
    Harada M; Miyahara T; Kajita-Kondo S; Kozakai A; Higuchi S; Otomo S; Kozuka H
    Res Commun Mol Pathol Pharmacol; 1994 Nov; 86(2):183-93. PubMed ID: 7881867
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Biological activity of fluorinated vitamin D analogs at C-26 and C-27 on human promyelocytic leukemia cells, HL-60.
    Inaba M; Okuno S; Nishizawa Y; Yukioka K; Otani S; Matsui-Yuasa I; Morisawa S; DeLuca HF; Morii H
    Arch Biochem Biophys; 1987 Nov; 258(2):421-5. PubMed ID: 2823715
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of hexafluoro-1,25-dihydroxyvitamin D3 and sodium butyrate combination on differentiation and proliferation of HL-60 leukemia cells.
    Yoshida M; Tanaka Y; Eguchi T; Ikekawa N; Saijo N
    Anticancer Res; 1992; 12(6B):1947-52. PubMed ID: 1363510
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human osteoblasts in culture metabolize both 1 alpha, 25-dihydroxyvitamin D3 and its precursor 25-hydroxyvitamin D3 into their respective lactones.
    Siu-Caldera ML; Zou L; Ehrlich MG; Schwartz ER; Ishizuka S; Reddy GS
    Endocrinology; 1995 Oct; 136(10):4195-203. PubMed ID: 7664636
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 1alpha,25-dihydroxyvitamin D3-24-hydroxylase (CYP24) hydroxylates the carbon at the end of the side chain (C-26) of the C-24-fluorinated analog of 1alpha,25-dihydroxyvitamin D3.
    Miyamoto Y; Shinki T; Yamamoto K; Ohyama Y; Iwasaki H; Hosotani R; Kasama T; Takayama H; Yamada S; Suda T
    J Biol Chem; 1997 May; 272(22):14115-9. PubMed ID: 9162038
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Increased biological potency of hexafluorinated analogs of 1,25-dihydroxyvitamin D3 on bovine parathyroid cells.
    Imanishi Y; Inaba M; Seki H; Koyama H; Nishizawa Y; Morii H; Otani S
    J Steroid Biochem Mol Biol; 1999; 70(4-6):243-8. PubMed ID: 10622414
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metabolic pathways from 1 alpha,25-dihydroxyvitamin D3 to 1 alpha,25-dihydroxyvitamin D3-26,23-lactone. Stereo-retained and stereo-selective lactonization.
    Ishizuka S; Norman AW
    J Biol Chem; 1987 May; 262(15):7165-70. PubMed ID: 3034884
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A highly potent 26,27-Hexafluoro-1a,25-dihydroxyvitamin D3 on calcification in SV40-transformed human fetal osteoblastic cells.
    Miyahara T; Simoura T; Osahune N; Uchida Y; Sakuma T; Nemoto N; Kozakai A; Takamura T; Yamazaki R; Higuchi S; Chiba H; Iba K; Sawada N
    Calcif Tissue Int; 2002 Jun; 70(6):488-95. PubMed ID: 12016462
    [TBL] [Abstract][Full Text] [Related]  

  • 17. C-25 hydroxylation of 1alpha,24(R)-dihydroxyvitamin D3 is catalyzed by 25-hydroxyvitamin D3-24-hydroxylase (CYP24A1): metabolism studies with human keratinocytes and rat recombinant CYP24A1.
    Astecker N; Bobrovnikova EA; Omdahl JL; Gennaro L; Vouros P; Schuster I; Uskokovic MR; Ishizuka S; Wang G; Reddy GS
    Arch Biochem Biophys; 2004 Nov; 431(2):261-70. PubMed ID: 15488475
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DNA binding property of vitamin D3 receptors associated with 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3.
    Inaba M; Okuno S; Inoue A; Nishizawa Y; Morii H; DeLuca HF
    Arch Biochem Biophys; 1989 Jan; 268(1):35-9. PubMed ID: 2463789
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel vitamin D3 derivatives, 26-homo-delta 22-dehydro-1 alpha,25(S)-dihydroxyvitamin D3 and 26-homo-delta 22-dehydro-1 alpha,25(R)-dihydroxyvitamin D3: preferential activity in c-myc mRNA production and in induction of phenotypic differentiation of HL-60 cells.
    Koizumi T; Nakao Y; Ishizuka S; Oshida J; Hara N; Ikekawa N; Fijita T
    Arch Biochem Biophys; 1990 Feb; 276(2):310-6. PubMed ID: 2407190
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Studies on an adherent variant of the human promyelomonocytic HL60 leukaemia cell line that constitutively expresses 25-hydroxyvitamin D3-24-hydroxylase activity which is inhibited by 1 alpha,25-dihydroxyvitamin D3.
    Hayes ME; Bayley D; Mawer EB
    J Mol Endocrinol; 1991 Dec; 7(3):185-95. PubMed ID: 1777040
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.