BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

152 related articles for article (PubMed ID: 8240420)

  • 1. Desulfuration of 6-mercaptopurine. The basis for the paradoxical cytotoxicity of thiopurines in cultured human leukemic cells.
    Adamson PC; Balis FM; Hawkins ME; Murphy RF; Poplack DG
    Biochem Pharmacol; 1993 Nov; 46(9):1627-36. PubMed ID: 8240420
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The cytotoxicity of thioguanine vs mercaptopurine in acute lymphoblastic leukemia.
    Adamson PC; Poplack DG; Balis FM
    Leuk Res; 1994 Nov; 18(11):805-10. PubMed ID: 7967706
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Modulation of thiopurine cytotoxicity in the HL-60 cell line by physiological concentrations of hypoxanthine.
    Zimm S; Johnson GE; Poplack DG
    Cancer Res; 1986 Dec; 46(12 Pt 1):6286-9. PubMed ID: 3465436
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Increased sensitivity to thiopurines in methylthioadenosine phosphorylase-deleted cancers.
    Coulthard SA; Redfern CP; Vikingsson S; Lindqvist-Appell M; Skoglund K; Jakobsen-Falk I; Hall AG; Taylor GA; Hogarth LA
    Mol Cancer Ther; 2011 Mar; 10(3):495-504. PubMed ID: 21282358
    [TBL] [Abstract][Full Text] [Related]  

  • 5. On the biochemical modulation of 6-mercaptopurine by methotrexate in murine WEHI-3b leukemia cells in vitro.
    Liliemark J; Pettersson B; Peterson C
    Leuk Res; 1992; 16(3):275-80. PubMed ID: 1373210
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differing contribution of thiopurine methyltransferase to mercaptopurine versus thioguanine effects in human leukemic cells.
    Dervieux T; Blanco JG; Krynetski EY; Vanin EF; Roussel MF; Relling MV
    Cancer Res; 2001 Aug; 61(15):5810-6. PubMed ID: 11479220
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Biochemical basis of the prevention of 6-thiopurine toxicity by the nucleobases, hypoxanthine and adenine.
    Hashimoto H; Kubota M; Shimizu T; Takimoto T; Kitoh T; Akiyama Y; Mikawa H
    Leuk Res; 1990; 14(11-12):1061-6. PubMed ID: 2280604
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential role of thiopurine methyltransferase in the cytotoxic effects of 6-mercaptopurine and 6-thioguanine on human leukemia cells.
    Karim H; Ghalali A; Lafolie P; Vitols S; Fotoohi AK
    Biochem Biophys Res Commun; 2013 Jul; 437(2):280-6. PubMed ID: 23811272
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Metabolic effects of thiopurine derivatives against human CCRF-CEM leukaemia cells.
    Shi RZ; Lyons SD; Christopherson RI
    Int J Biochem Cell Biol; 1998 Aug; 30(8):885-95. PubMed ID: 9744080
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 6-Mercaptopurine: cytotoxicity and biochemical pharmacology in human malignant T-lymphoblasts.
    Bökkerink JP; Stet EH; De Abreu RA; Damen FJ; Hulscher TW; Bakker MA; van Baal JA
    Biochem Pharmacol; 1993 Apr; 45(7):1455-63. PubMed ID: 7682415
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 6-Thioguanine-induced growth arrest in 6-mercaptopurine-resistant human leukemia cells.
    Morgan CJ; Chawdry RN; Smith AR; Siravo-Sagraves G; Trewyn RW
    Cancer Res; 1994 Oct; 54(20):5387-93. PubMed ID: 7923170
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Three Faces of Mercaptopurine Cytotoxicity In Vitro: Methylation, Nucleotide Homeostasis, and Deoxythioguanosine in DNA.
    Coulthard SA; McGarrity S; Sahota K; Berry P; Redfern CPF
    Drug Metab Dispos; 2018 Aug; 46(8):1191-1199. PubMed ID: 29884651
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Increased concentrations of methylated 6-mercaptopurine metabolites and 6-thioguanine nucleotides in human leukemic cells in vitro by methotrexate.
    Giverhaug T; Loennechen T; Aarbakke J
    Biochem Pharmacol; 1998 May; 55(10):1641-6. PubMed ID: 9634000
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Purine de novo synthesis as the basis of synergism of methotrexate and 6-mercaptopurine in human malignant lymphoblasts of different lineages.
    Bökkerink JP; Bakker MA; Hulscher TW; De Abreu RA; Schretlen ED
    Biochem Pharmacol; 1988 Jun; 37(12):2321-7. PubMed ID: 2455519
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Colonic microbiota can promote rapid local improvement of murine colitis by thioguanine independently of T lymphocytes and host metabolism.
    Oancea I; Movva R; Das I; Aguirre de Cárcer D; Schreiber V; Yang Y; Purdon A; Harrington B; Proctor M; Wang R; Sheng Y; Lobb M; Lourie R; Ó Cuív P; Duley JA; Begun J; Florin TH
    Gut; 2017 Jan; 66(1):59-69. PubMed ID: 27411368
    [TBL] [Abstract][Full Text] [Related]  

  • 16. On the paradoxically concentration-dependent metabolism of 6-mercaptopurine in WEHI-3b murine leukemia cells.
    Liliemark J; Pettersson B; Engberg B; Lafolie P; Masquelier M; Peterson C
    Cancer Res; 1990 Jan; 50(1):108-12. PubMed ID: 2293545
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The effect of thiopurine methyltransferase expression on sensitivity to thiopurine drugs.
    Coulthard SA; Hogarth LA; Little M; Matheson EC; Redfern CP; Minto L; Hall AG
    Mol Pharmacol; 2002 Jul; 62(1):102-9. PubMed ID: 12065760
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Induction of erythroid differentiation in vitro by purines and purine analogues.
    Gusella JF; Housman D
    Cell; 1976 Jun; 8(2):263-9. PubMed ID: 971485
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Impaired transport as a mechanism of resistance to thiopurines in human T-lymphoblastic leukemia cells.
    Fotoohi AK; Lindqvist M; Peterson C; Albertioni F
    Nucleosides Nucleotides Nucleic Acids; 2006; 25(9-11):1039-44. PubMed ID: 17065061
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The effects of 6-mercaptopurine nucleotide derivatives on the growth and survival of 6-mercaptopurine-sensitive and -resistant cell culture lines.
    Johnston HP; Hawley P; White SE; Gibson I; Tidd DM
    Br J Cancer; 1985 Apr; 51(4):505-14. PubMed ID: 3838480
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.