These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 8247012)

  • 1. Decreased levels of internalized thyrotropin-releasing hormone receptors after uncoupling from guanine nucleotide-binding protein and phospholipase-C.
    Nussenzveig DR; Heinflink M; Gershengorn MC
    Mol Endocrinol; 1993 Sep; 7(9):1105-11. PubMed ID: 8247012
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A disulfide bonding interaction role for cysteines in the extracellular domain of the thyrotropin-releasing hormone receptor.
    Cook JV; McGregor A; Lee T; Milligan G; Eidne KA
    Endocrinology; 1996 Jul; 137(7):2851-8. PubMed ID: 8770906
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A constitutively active mutant thyrotropin-releasing hormone receptor is chronically down-regulated in pituitary cells: evidence using chlordiazepoxide as a negative antagonist.
    Heinflink M; Nussenzveig DR; Grimberg H; Lupu-Meiri M; Oron Y; Gershengorn MC
    Mol Endocrinol; 1995 Nov; 9(11):1455-60. PubMed ID: 8584022
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Internalization of the gastrin-releasing peptide receptor is mediated by both phospholipase C-dependent and -independent processes.
    Benya RV; Akeson M; Mrozinski J; Jensen RT; Battey JF
    Mol Pharmacol; 1994 Sep; 46(3):495-501. PubMed ID: 7935330
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Thyrotropin-releasing hormone and gonadotropin-releasing hormone receptors activate phospholipase C by coupling to the guanosine triphosphate-binding proteins Gq and G11.
    Hsieh KP; Martin TF
    Mol Endocrinol; 1992 Oct; 6(10):1673-81. PubMed ID: 1333052
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Altered ligand dissociation rates in thyrotropin-releasing hormone receptors mutated in glutamine 105 of transmembrane helix III.
    del Camino D; Barros F; Pardo LA; de la Peña P
    Biochemistry; 1997 Mar; 36(11):3308-18. PubMed ID: 9116009
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In vivo activity of a phospholipase C inhibitor, 1-(6-((17beta-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione (U73122), in acute and chronic inflammatory reactions.
    Hou C; Kirchner T; Singer M; Matheis M; Argentieri D; Cavender D
    J Pharmacol Exp Ther; 2004 May; 309(2):697-704. PubMed ID: 14730005
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Distinct roles for arginines in transmembrane helices 6 and 7 of the thyrotropin-releasing hormone receptor.
    Perlman JH; Laakkonen L; Osman R; Gershengorn MC
    Mol Pharmacol; 1995 Mar; 47(3):480-4. PubMed ID: 7700246
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interactions between conserved residues in transmembrane helices 1, 2, and 7 of the thyrotropin-releasing hormone receptor.
    Perlman JH; Colson AO; Wang W; Bence K; Osman R; Gershengorn MC
    J Biol Chem; 1997 May; 272(18):11937-42. PubMed ID: 9115256
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of the extracellular loops of the thyrotropin-releasing hormone receptor: evidence for an initial interaction with thyrotropin-releasing hormone.
    Perlman JH; Colson AO; Jain R; Czyzewski B; Cohen LA; Osman R; Gershengorn MC
    Biochemistry; 1997 Dec; 36(50):15670-6. PubMed ID: 9398295
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Juxtamembrane regions in the third intracellular loop of the thyrotropin-releasing hormone receptor type 1 are important for coupling to Gq.
    Buck F; Wang W; Harder S; Brathwaite C; Bruhn TO; Gershengorn MC
    Endocrinology; 2000 Oct; 141(10):3717-22. PubMed ID: 11014227
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 1-[6-[[(17beta)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-1H-pyrrole-2,5-dione (U73122) selectively inhibits Kir3 and BK channels in a phospholipase C-independent fashion.
    Klose A; Huth T; Alzheimer C
    Mol Pharmacol; 2008 Nov; 74(5):1203-14. PubMed ID: 18682550
    [TBL] [Abstract][Full Text] [Related]  

  • 13. U-73122, an aminosteroid phospholipase C antagonist, noncompetitively inhibits thyrotropin-releasing hormone effects in GH3 rat pituitary cells.
    Smallridge RC; Kiang JG; Gist ID; Fein HG; Galloway RJ
    Endocrinology; 1992 Oct; 131(4):1883-8. PubMed ID: 1396332
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Signal transduction, desensitization, and recovery of responses to thyrotropin-releasing hormone after inhibition of receptor internalization.
    Yu R; Hinkle PM
    Mol Endocrinol; 1998 May; 12(5):737-49. PubMed ID: 9605936
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Polarity of TRH receptors in transfected MDCK cells is independent of endocytosis signals and G protein coupling.
    Yeaman C; Heinflink M; Falck-Pedersen E; Rodriguez-Boulan E; Gershengorn MC
    Am J Physiol; 1996 Mar; 270(3 Pt 1):C753-62. PubMed ID: 8638654
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Constitutive activity of native thyrotropin-releasing hormone receptors revealed using a protein kinase C-responsive reporter gene.
    Jinsi-Parimoo A; Gershengorn MC
    Endocrinology; 1997 Apr; 138(4):1471-5. PubMed ID: 9075704
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Thyrotropin-releasing hormone binding to the mouse pituitary receptor does not involve ionic interactions. A model for neutral peptide binding to G protein-coupled receptors.
    Perlman JH; Nussenzveig DR; Osman R; Gershengorn MC
    J Biol Chem; 1992 Dec; 267(34):24413-7. PubMed ID: 1332958
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Importance of extracellular domains for ligand binding in the thyrotropin-releasing hormone receptor.
    Han B; Tashjian AH
    Mol Endocrinol; 1995 Dec; 9(12):1708-19. PubMed ID: 8614407
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A refined model of the thyrotropin-releasing hormone (TRH) receptor binding pocket. Experimental analysis and energy minimization of the complex between TRH and TRH receptor.
    Perlman JH; Laakkonen LJ; Guarnieri F; Osman R; Gershengorn MC
    Biochemistry; 1996 Jun; 35(24):7643-50. PubMed ID: 8672465
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Agonist-stimulated internalization of the thyrotropin-releasing hormone receptor is dependent on two domains in the receptor carboxyl terminus.
    Nussenzveig DR; Heinflink M; Gershengorn MC
    J Biol Chem; 1993 Feb; 268(4):2389-92. PubMed ID: 8381407
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.