BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

440 related articles for article (PubMed ID: 8248208)

  • 1. Altered regulation of G1 cyclins in senescent human diploid fibroblasts: accumulation of inactive cyclin E-Cdk2 and cyclin D1-Cdk2 complexes.
    Dulić V; Drullinger LF; Lees E; Reed SI; Stein GH
    Proc Natl Acad Sci U S A; 1993 Dec; 90(23):11034-8. PubMed ID: 8248208
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanisms of senescence and differentiation in human fibroblasts.
    Stein GH; Drullinger LF; Soulard A; Dulić V
    Mol Cell Biol; 1999 Mar; 19(3):2109-17. PubMed ID: 10022898
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Investigation of the role of G1/S cell cycle mediators in cellular senescence.
    Afshari CA; Vojta PJ; Annab LA; Futreal PA; Willard TB; Barrett JC
    Exp Cell Res; 1993 Dec; 209(2):231-7. PubMed ID: 8262140
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reduction of Cdc25A contributes to cyclin E1-Cdk2 inhibition at senescence in human mammary epithelial cells.
    Sandhu C; Donovan J; Bhattacharya N; Stampfer M; Worland P; Slingerland J
    Oncogene; 2000 Nov; 19(47):5314-23. PubMed ID: 11103932
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effects of cyclin D1 overexpression on G1 progression-related events.
    Imoto M; Doki Y; Jiang W; Han EK; Weinstein IB
    Exp Cell Res; 1997 Oct; 236(1):173-80. PubMed ID: 9344597
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cyclin D2 activates Cdk2 in preference to Cdk4 in human breast epithelial cells.
    Sweeney KJ; Sarcevic B; Sutherland RL; Musgrove EA
    Oncogene; 1997 Mar; 14(11):1329-40. PubMed ID: 9178893
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutant p53 can delay growth arrest and loss of CDK2 activity in senescing human fibroblasts without reducing p21(WAF1) expression.
    Wyllie F; Haughton M; Bartek J; Rowson J; Wynford-Thomas D
    Exp Cell Res; 2003 May; 285(2):236-42. PubMed ID: 12706118
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of the melanoma cell cycle and regulation at the G1/S transition by 12-O-tetradecanoylphorbol-13-acetate (TPA) by modulation of CDK2 activity.
    Coppock DL; Buffolino P; Kopman C; Nathanson L
    Exp Cell Res; 1995 Nov; 221(1):92-102. PubMed ID: 7589260
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inducible expression of cyclin D1 in T-47D human breast cancer cells is sufficient for Cdk2 activation and pRB hyperphosphorylation.
    Musgrove EA; Sarcevic B; Sutherland RL
    J Cell Biochem; 1996 Mar; 60(3):363-78. PubMed ID: 8867812
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cyclin E/Cdk2 activity is controlled by different mechanisms in the G0 and G1 phases of the cell cycle.
    Bresnahan WA; Boldogh I; Ma T; Albrecht T; Thompson EA
    Cell Growth Differ; 1996 Oct; 7(10):1283-90. PubMed ID: 8891332
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Disruption of the actin cytoskeleton leads to inhibition of mitogen-induced cyclin E expression, Cdk2 phosphorylation, and nuclear accumulation of the retinoblastoma protein-related p107 protein.
    Reshetnikova G; Barkan R; Popov B; Nikolsky N; Chang LS
    Exp Cell Res; 2000 Aug; 259(1):35-53. PubMed ID: 10942577
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cyclin-dependent kinase-2 (Cdk2) forms an inactive complex with cyclin D1 since Cdk2 associated with cyclin D1 is not phosphorylated by Cdk7-cyclin-H.
    Higashi H; Suzuki-Takahashi I; Saitoh S; Segawa K; Taya Y; Okuyama A; Nishimura S; Kitagawa M
    Eur J Biochem; 1996 Apr; 237(2):460-7. PubMed ID: 8647086
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Uncoupling between phenotypic senescence and cell cycle arrest in aging p21-deficient fibroblasts.
    Dulić V; Beney GE; Frebourg G; Drullinger LF; Stein GH
    Mol Cell Biol; 2000 Sep; 20(18):6741-54. PubMed ID: 10958672
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differential activation of cyclin and cyclin-dependent kinase genes by adenovirus E1A12S cDNA product.
    Ishii T; Shimizu M; Kanayama Y; Nakada S; Nojima H; Oda K
    Exp Cell Res; 1993 Oct; 208(2):407-14. PubMed ID: 8375470
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human cyclin-dependent kinase 2 is activated during the S and G2 phases of the cell cycle and associates with cyclin A.
    Rosenblatt J; Gu Y; Morgan DO
    Proc Natl Acad Sci U S A; 1992 Apr; 89(7):2824-8. PubMed ID: 1532660
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Association of human cyclin E with a periodic G1-S phase protein kinase.
    Dulić V; Lees E; Reed SI
    Science; 1992 Sep; 257(5078):1958-61. PubMed ID: 1329201
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation of cdk4 and cdk2 during rat liver regeneration is associated with intranuclear rearrangements of cyclin-cdk complexes.
    Jaumot M; Estanyol JM; Serratosa J; Agell N; Bachs O
    Hepatology; 1999 Feb; 29(2):385-95. PubMed ID: 9918914
    [TBL] [Abstract][Full Text] [Related]  

  • 18. v-Jun overrides the mitogen dependence of S-phase entry by deregulating retinoblastoma protein phosphorylation and E2F-pocket protein interactions as a consequence of enhanced cyclin E-cdk2 catalytic activity.
    Clark W; Black EJ; MacLaren A; Kruse U; LaThangue N; Vogt PK; Gillespie DA
    Mol Cell Biol; 2000 Apr; 20(7):2529-42. PubMed ID: 10713176
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of a Myc-dependent step during the formation of active G1 cyclin-cdk complexes.
    Steiner P; Philipp A; Lukas J; Godden-Kent D; Pagano M; Mittnacht S; Bartek J; Eilers M
    EMBO J; 1995 Oct; 14(19):4814-26. PubMed ID: 7588611
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Selective repression of growth-regulating cdk2, cyclin E and E2F1 genes in human cell senescence.
    Kanazawa S; Fujiwara Y; Mizuno K
    Kobe J Med Sci; 1994 Dec; 40(5-6):165-74. PubMed ID: 7542356
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.