These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

344 related articles for article (PubMed ID: 8248258)

  • 1. Germ-line transmission and developmental regulation of a 150-kb yeast artificial chromosome containing the human beta-globin locus in transgenic mice.
    Gaensler KM; Kitamura M; Kan YW
    Proc Natl Acad Sci U S A; 1993 Dec; 90(23):11381-5. PubMed ID: 8248258
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The human beta globin locus introduced by YAC transfer exhibits a specific and reproducible pattern of developmental regulation in transgenic mice.
    Porcu S; Kitamura M; Witkowska E; Zhang Z; Mutero A; Lin C; Chang J; Gaensler KM
    Blood; 1997 Dec; 90(11):4602-9. PubMed ID: 9373272
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synergistic regulation of human beta-globin gene switching by locus control region elements HS3 and HS4.
    Bungert J; Davé U; Lim KC; Lieuw KH; Shavit JA; Liu Q; Engel JD
    Genes Dev; 1995 Dec; 9(24):3083-96. PubMed ID: 8543153
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Transgenic mice containing a 248-kb yeast artificial chromosome carrying the human beta-globin locus display proper developmental control of human globin genes.
    Peterson KR; Clegg CH; Huxley C; Josephson BM; Haugen HS; Furukawa T; Stamatoyannopoulos G
    Proc Natl Acad Sci U S A; 1993 Aug; 90(16):7593-7. PubMed ID: 8356061
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Deletion of the human beta-globin LCR 5'HS4 or 5'HS1 differentially affects beta-like globin gene expression in beta-YAC transgenic mice.
    Fedosyuk H; Peterson KR
    Blood Cells Mol Dis; 2007; 39(1):44-55. PubMed ID: 17433733
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sequences in the (A)gamma-delta intergenic region are not required for stage-specific regulation of the human beta-globin gene locus.
    Gaensler KM; Zhang Z; Lin C; Yang S; Hardt K; Flebbe-Rehwaldt L
    Proc Natl Acad Sci U S A; 2003 Mar; 100(6):3374-9. PubMed ID: 12629213
    [TBL] [Abstract][Full Text] [Related]  

  • 7. LCR-dependent gene expression in beta-globin YAC transgenics: detailed structural studies validate functional analysis even in the presence of fragmented YACs.
    Peterson KR; Navas PA; Li Q; Stamatoyannopoulos G
    Hum Mol Genet; 1998 Dec; 7(13):2079-88. PubMed ID: 9817925
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Proper developmental control of human globin genes reproduced by transgenic mice containing a 160-kb BAC carrying the human beta-globin locus.
    Huang Y; Liu DP; Wu L; Li TC; Wu M; Feng DX; Liang CC
    Blood Cells Mol Dis; 2000 Dec; 26(6):598-610. PubMed ID: 11358351
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Use of yeast artificial chromosomes (YACs) for studying control of gene expression: correct regulation of the genes of a human beta-globin locus YAC following transfer to mouse erythroleukemia cell lines.
    Peterson KR; Zitnik G; Huxley C; Lowrey CH; Gnirke A; Leppig KA; Papayannopoulou T; Stamatoyannopoulos G
    Proc Natl Acad Sci U S A; 1993 Dec; 90(23):11207-11. PubMed ID: 8248229
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Correct function of the locus control region may require passage through a nonerythroid cellular environment.
    Vassilopoulos G; Navas PA; Skarpidi E; Peterson KR; Lowrey CH; Papayannopoulou T; Stamatoyannopoulos G
    Blood; 1999 Jan; 93(2):703-12. PubMed ID: 9885233
    [TBL] [Abstract][Full Text] [Related]  

  • 11. beta-YAC transgenic mice for studying LCR function.
    Peterson KR; Navas PA; Stamatoyannopoulos G
    Ann N Y Acad Sci; 1998 Jun; 850():28-37. PubMed ID: 9668524
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Establishment of cell lines that exhibit correct ontogenic stage-specific gene expression profiles from tissues of yeast artificial chromosome transgenic mice using chemically induced growth signals.
    Blau CA; Peterson KR
    Methods Mol Biol; 2006; 349():163-73. PubMed ID: 17071982
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutation of a transcriptional motif of a distant regulatory element reduces the expression of embryonic and fetal globin genes.
    Navas PA; Swank RA; Yu M; Peterson KR; Stamatoyannopoulos G
    Hum Mol Genet; 2003 Nov; 12(22):2941-8. PubMed ID: 14506128
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Developmental specificity of the interaction between the locus control region and embryonic or fetal globin genes in transgenic mice with an HS3 core deletion.
    Navas PA; Peterson KR; Li Q; Skarpidi E; Rohde A; Shaw SE; Clegg CH; Asano H; Stamatoyannopoulos G
    Mol Cell Biol; 1998 Jul; 18(7):4188-96. PubMed ID: 9632803
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The 5'HS4 core element of the human beta-globin locus control region is required for high-level globin gene expression in definitive but not in primitive erythropoiesis.
    Navas PA; Peterson KR; Li Q; McArthur M; Stamatoyannopoulos G
    J Mol Biol; 2001 Sep; 312(1):17-26. PubMed ID: 11545582
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transgenic analysis of a 100-kb human beta-globin cluster-containing DNA fragment propagated as a bacterial artificial chromosome.
    Kaufman RM; Pham CT; Ley TJ
    Blood; 1999 Nov; 94(9):3178-84. PubMed ID: 10556205
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effect of deletion of 5'HS3 or 5'HS2 of the human beta-globin locus control region on the developmental regulation of globin gene expression in beta-globin locus yeast artificial chromosome transgenic mice.
    Peterson KR; Clegg CH; Navas PA; Norton EJ; Kimbrough TG; Stamatoyannopoulos G
    Proc Natl Acad Sci U S A; 1996 Jun; 93(13):6605-9. PubMed ID: 8692864
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Use of yeast artificial chromosomes (YACs) in studies of mammalian development: production of beta-globin locus YAC mice carrying human globin developmental mutants.
    Peterson KR; Li QL; Clegg CH; Furukawa T; Navas PA; Norton EJ; Kimbrough TG; Stamatoyannopoulos G
    Proc Natl Acad Sci U S A; 1995 Jun; 92(12):5655-9. PubMed ID: 7539923
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice.
    Ryan TM; Behringer RR; Martin NC; Townes TM; Palmiter RD; Brinster RL
    Genes Dev; 1989 Mar; 3(3):314-23. PubMed ID: 2721958
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A 5' control region of the human epsilon-globin gene is sufficient for embryonic specificity in transgenic mice.
    Shih DM; Wall RJ; Shapiro SG
    J Biol Chem; 1993 Feb; 268(5):3066-71. PubMed ID: 8428985
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.