These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

232 related articles for article (PubMed ID: 8248802)

  • 1. Engineered biosynthesis of novel polyketides.
    McDaniel R; Ebert-Khosla S; Hopwood DA; Khosla C
    Science; 1993 Dec; 262(5139):1546-50. PubMed ID: 8248802
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Iterative type II polyketide synthases, cyclases and ketoreductases exhibit context-dependent behavior in the biosynthesis of linear and angular decapolyketides.
    Meurer G; Gerlitz M; Wendt-Pienkowski E; Vining LC; Rohr J; Hutchinson CR
    Chem Biol; 1997 Jun; 4(6):433-43. PubMed ID: 9224566
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cloning, sequencing and analysis of the enterocin biosynthesis gene cluster from the marine isolate 'Streptomyces maritimus': evidence for the derailment of an aromatic polyketide synthase.
    Piel J; Hertweck C; Shipley PR; Hunt DM; Newman MS; Moore BS
    Chem Biol; 2000 Dec; 7(12):943-55. PubMed ID: 11137817
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.
    Kantola J; Blanco G; Hautala A; Kunnari T; Hakala J; Mendez C; Ylihonko K; Mäntsälä P; Salas J
    Chem Biol; 1997 Oct; 4(10):751-5. PubMed ID: 9375253
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Engineered biosynthesis of novel polyketides: influence of a downstream enzyme on the catalytic specificity of a minimal aromatic polyketide synthase.
    McDaniel R; Ebert-Khosla S; Fu H; Hopwood DA; Khosla C
    Proc Natl Acad Sci U S A; 1994 Nov; 91(24):11542-6. PubMed ID: 7972098
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ketosynthases in the initiation and elongation modules of aromatic polyketide synthases have orthogonal acyl carrier protein specificity.
    Tang Y; Lee TS; Kobayashi S; Khosla C
    Biochemistry; 2003 Jun; 42(21):6588-95. PubMed ID: 12767243
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A gene cluster encoding resistomycin biosynthesis in Streptomyces resistomycificus; exploring polyketide cyclization beyond linear and angucyclic patterns.
    Jakobi K; Hertweck C
    J Am Chem Soc; 2004 Mar; 126(8):2298-9. PubMed ID: 14982421
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Engineered biosynthesis of novel polyketides: properties of the whiE aromatase/cyclase.
    Alvarez MA; Fu H; Khosla C; Hopwood DA; Bailey JE
    Nat Biotechnol; 1996 Mar; 14(3):335-8. PubMed ID: 9630896
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Engineered intermodular and intramodular polyketide synthase fusions.
    McDaniel R; Kao CM; Hwang SJ; Khosla C
    Chem Biol; 1997 Sep; 4(9):667-74. PubMed ID: 9331407
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Engineered biosynthesis of novel polyketides: stereochemical course of two reactions catalyzed by a polyketide synthase.
    Fu H; McDaniel R; Hopwood DA; Khosla C
    Biochemistry; 1994 Aug; 33(31):9321-6. PubMed ID: 8049233
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Engineered biosynthesis of regioselectively modified aromatic polyketides using bimodular polyketide synthases.
    Tang Y; Lee TS; Khosla C
    PLoS Biol; 2004 Feb; 2(2):E31. PubMed ID: 14966533
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Engineered biosynthesis of novel polyketides: evidence for temporal, but not regiospecific, control of cyclization of an aromatic polyketide precursor.
    Fu H; Hopwood DA; Khosla C
    Chem Biol; 1994 Dec; 1(4):205-10. PubMed ID: 9383392
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The granaticin biosynthetic gene cluster of Streptomyces violaceoruber Tü22: sequence analysis and expression in a heterologous host.
    Ichinose K; Bedford DJ; Tornus D; Bechthold A; Bibb MJ; Revill WP; Floss HG; Hopwood DA
    Chem Biol; 1998 Nov; 5(11):647-59. PubMed ID: 9831526
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Engineering of complex polyketide biosynthesis--insights from sequencing of the monensin biosynthetic gene cluster.
    Leadlay PF; Staunton J; Oliynyk M; Bisang C; Cortés J; Frost E; Hughes-Thomas ZA; Jones MA; Kendrew SG; Lester JB; Long PF; McArthur HA; McCormick EL; Oliynyk Z; Stark CB; Wilkinson CJ
    J Ind Microbiol Biotechnol; 2001 Dec; 27(6):360-7. PubMed ID: 11774001
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rational design of aromatic polyketide natural products by recombinant assembly of enzymatic subunits.
    McDaniel R; Ebert-Khosla S; Hopwood DA; Khosla C
    Nature; 1995 Jun; 375(6532):549-54. PubMed ID: 7791871
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Engineered biosynthesis of a complete macrolactone in a heterologous host.
    Kao CM; Katz L; Khosla C
    Science; 1994 Jul; 265(5171):509-12. PubMed ID: 8036492
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Deciphering the mechanism for the assembly of aromatic polyketides by a bacterial polyketide synthase.
    Shen B; Hutchinson CR
    Proc Natl Acad Sci U S A; 1996 Jun; 93(13):6600-4. PubMed ID: 8692863
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Heterologous expression, purification, reconstitution and kinetic analysis of an extended type II polyketide synthase.
    Zawada RJ; Khosla C
    Chem Biol; 1999 Sep; 6(9):607-15. PubMed ID: 10467128
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A host-vector system for analysis and manipulation of rifamycin polyketide biosynthesis in Amycolatopsis mediterranei.
    Hu Z; Hunziker D; Hutchinson CR; Khosla C
    Microbiology (Reading); 1999 Sep; 145 ( Pt 9)():2335-2341. PubMed ID: 10517586
    [TBL] [Abstract][Full Text] [Related]  

  • 20. C-O bond formation by polyketide synthases.
    Kwon HJ; Smith WC; Scharon AJ; Hwang SH; Kurth MJ; Shen B
    Science; 2002 Aug; 297(5585):1327-30. PubMed ID: 12193782
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.