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2. Structural requirements for a specificity switch and for maintenance of affinity using mutational analysis of a phage-displayed anti-arsonate antibody of Fab heavy chain first complementarity-determining region. Wong YW; Gill DS; Parhami-Seren B; Short MK; Sompuram SR; Margolies MN J Immunol; 1998 Jun; 160(12):5990-7. PubMed ID: 9637513 [TBL] [Abstract][Full Text] [Related]
3. Contribution of heavy chain junctional amino acid diversity to antibody affinity among p-azophenylarsonate-specific antibodies. Parhami-Seren B; Margolies MN J Immunol; 1996 Sep; 157(5):2066-72. PubMed ID: 8757328 [TBL] [Abstract][Full Text] [Related]
4. Evaluation of loss and change of specificity resulting from random mutagenesis of an antibody VH region. Casson LP; Manser T J Immunol; 1995 Dec; 155(12):5647-54. PubMed ID: 7499849 [TBL] [Abstract][Full Text] [Related]
5. Clustered H chain somatic mutations shared by anti-p-azophenylarsonate antibodies confer enhanced affinity and ablate the cross-reactive idiotype. Parhami-Seren B; Wysocki LJ; Margolies MN; Sharon J J Immunol; 1990 Oct; 145(7):2340-6. PubMed ID: 2118935 [TBL] [Abstract][Full Text] [Related]
6. Structural characterization of H chain-associated idiotopes of anti-p-azophenylarsonate monoclonal antibodies. Parhami-Seren B; Sharon J; Margolies MN J Immunol; 1990 Jun; 144(11):4426-33. PubMed ID: 2111347 [TBL] [Abstract][Full Text] [Related]
7. Molecular analysis of original antigenic sin. I. Clonal selection, somatic mutation, and isotype switching during a memory B cell response. Fish S; Zenowich E; Fleming M; Manser T J Exp Med; 1989 Oct; 170(4):1191-209. PubMed ID: 2477487 [TBL] [Abstract][Full Text] [Related]
9. The amino acid residues at the VH-D-JH junctions affect the affinity of anti-p-azophenylarsonate antibodies. Parhami-Seren B; Wysocki L; Margolies MN J Immunol; 1989 Dec; 143(12):4090-7. PubMed ID: 2512349 [TBL] [Abstract][Full Text] [Related]
10. Modulation of antibody affinity by an engineered amino acid substitution. Wong YW; Kussie PH; Parhami-Seren B; Margolies MN J Immunol; 1995 Apr; 154(7):3351-8. PubMed ID: 7897218 [TBL] [Abstract][Full Text] [Related]
11. Tolerance of single, but not multiple, amino acid replacements in antibody VH CDR 2: a means of minimizing B cell wastage from somatic hypermutation? Brown M; Rittenburg MB; Chen C; Roberts VA J Immunol; 1996 May; 156(9):3285-91. PubMed ID: 8617951 [TBL] [Abstract][Full Text] [Related]
12. Use of JH4 joining segment gene by an anti-arsonate antibody that bears the major A-strain cross-reactive idiotype but displays diminished antigen binding. Slaughter CA; Jeske DJ; Kuziel WA; Milner EC; Capra JD J Immunol; 1984 Jun; 132(6):3164-71. PubMed ID: 6427333 [TBL] [Abstract][Full Text] [Related]
13. Analysis of antigen binding and idiotypic expression by antibodies with polyglycine-replaced complementarity-determining regions. Sompuram SR; Den W; Sharon J J Immunol; 1996 Feb; 156(3):1071-81. PubMed ID: 8557981 [TBL] [Abstract][Full Text] [Related]
14. Conservation of binding site geometry among p-azophenylarsonate-specific antibodies. Parhami-Seren B; Kussie PH; Strong RK; Margolies MN J Immunol; 1993 Mar; 150(5):1829-37. PubMed ID: 8436818 [TBL] [Abstract][Full Text] [Related]
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16. Rheumatoid factor specificity of a VH3-encoded antibody is dependent on the heavy chain CDR3 region and is independent of protein A binding. Zhang M; Majid A; Bardwell P; Vee C; Davidson A J Immunol; 1998 Sep; 161(5):2284-9. PubMed ID: 9725222 [TBL] [Abstract][Full Text] [Related]
17. Structural correlates of high antibody affinity: three engineered amino acid substitutions can increase the affinity of an anti-p-azophenylarsonate antibody 200-fold. Sharon J Proc Natl Acad Sci U S A; 1990 Jun; 87(12):4814-7. PubMed ID: 2352950 [TBL] [Abstract][Full Text] [Related]
18. Regulation of azophenylarsonate-specific repertoire expression. II. Fine specificity and isotype heterogeneity of anti-arsonate antibodies. Sigal NH J Immunol; 1983 Oct; 131(4):1889-94. PubMed ID: 6194218 [TBL] [Abstract][Full Text] [Related]
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20. B cell deletion, anergy, and receptor editing in "knock in" mice targeted with a germline-encoded or somatically mutated anti-DNA heavy chain. Pewzner-Jung Y; Friedmann D; Sonoda E; Jung S; Rajewsky K; Eilat D J Immunol; 1998 Nov; 161(9):4634-45. PubMed ID: 9794392 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]