BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

548 related articles for article (PubMed ID: 8257416)

  • 1. Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.
    Arcaro A; Wymann MP
    Biochem J; 1993 Dec; 296 ( Pt 2)(Pt 2):297-301. PubMed ID: 8257416
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Platelet-derived growth factor-induced phosphatidylinositol 3-kinase activation mediates actin rearrangements in fibroblasts.
    Wymann M; Arcaro A
    Biochem J; 1994 Mar; 298 Pt 3(Pt 3):517-20. PubMed ID: 8141762
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effect of wortmannin and 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002) on N-formyl-methionyl-leucyl-phenylalanine-induced phospholipase D activation in differentiated HL60 cells: possible involvement of phosphatidylinositol 3-kinase in phospholipase D activation.
    Nakamura M; Nakashima S; Katagiri Y; Nozawa Y
    Biochem Pharmacol; 1997 Jun; 53(12):1929-36. PubMed ID: 9256168
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of neutrophil oxidative burst and granule secretion by wortmannin: potential role of MAP kinase and renaturable kinases.
    Sue-A-Quan AK; Fialkow L; Vlahos CJ; Schelm JA; Grinstein S; Butler J; Downey GP
    J Cell Physiol; 1997 Jul; 172(1):94-108. PubMed ID: 9207930
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinase.
    Okada T; Sakuma L; Fukui Y; Hazeki O; Ui M
    J Biol Chem; 1994 Feb; 269(5):3563-7. PubMed ID: 8106399
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of phosphatidylinositol 3-kinase by concanavalin A through dual signaling pathways, G-protein-coupled and phosphotyrosine-related, and an essential role of the G-protein-coupled signals for the lectin-induced respiratory burst in human monocytic THP-1 cells.
    Matsuo T; Hazeki K; Hazeki O; Katada T; Ui M
    Biochem J; 1996 Apr; 315 ( Pt 2)(Pt 2):505-12. PubMed ID: 8615821
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphatidylinositol (3,4,5)-trisphosphate stimulates phosphorylation of pleckstrin in human platelets.
    Zhang J; Falck JR; Reddy KK; Abrams CS; Zhao W; Rittenhouse SE
    J Biol Chem; 1995 Sep; 270(39):22807-10. PubMed ID: 7559410
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phosphatidylinositol 3-kinase mediates chemoattractant-stimulated, CD11b/CD18-dependent cell-cell adhesion of human neutrophils: evidence for an ERK-independent pathway.
    Capodici C; Hanft S; Feoktistov M; Pillinger MH
    J Immunol; 1998 Feb; 160(4):1901-9. PubMed ID: 9469452
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cyclic AMP-increasing agents interfere with chemoattractant-induced respiratory burst in neutrophils as a result of the inhibition of phosphatidylinositol 3-kinase rather than receptor-operated Ca2+ influx.
    Ahmed MU; Hazeki K; Hazeki O; Katada T; Ui M
    J Biol Chem; 1995 Oct; 270(40):23816-22. PubMed ID: 7559558
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of phosphatidylinositol 3-kinase activity and phosphatidylinositol 3,4,5-trisphosphate accumulation by neutrophil priming agents.
    Cadwallader KA; Condliffe AM; McGregor A; Walker TR; White JF; Stephens LR; Chilvers ER
    J Immunol; 2002 Sep; 169(6):3336-44. PubMed ID: 12218155
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Antagonists of phosphatidylinositol 3-kinase block activation of several novel protein kinases in neutrophils.
    Ding J; Vlahos CJ; Liu R; Brown RF; Badwey JA
    J Biol Chem; 1995 May; 270(19):11684-91. PubMed ID: 7744808
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protein kinase C activity is not involved in N-formylmethionyl-leucyl-phenylalanine-induced phospholipase D activation in human neutrophils, but is essential for concomitant NADPH oxidase activation: studies with a staurosporine analogue with improved selectivity for protein kinase C.
    Kessels GC; Krause KH; Verhoeven AJ
    Biochem J; 1993 Jun; 292 ( Pt 3)(Pt 3):781-5. PubMed ID: 8391255
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Enhancement of chemotactic peptide-induced activation of phosphoinositide 3-kinase by granulocyte-macrophage colony-stimulating factor and its relation to the cytokine-mediated priming of neutrophil superoxide-anion production.
    Kodama T; Hazeki K; Hazeki O; Okada T; Ui M
    Biochem J; 1999 Jan; 337 ( Pt 2)(Pt 2):201-9. PubMed ID: 9882616
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The phosphatidylinositol 3-kinase inhibitor wortmannin markedly reduces chemotactic peptide-induced locomotion and increases in cytoskeletal actin in human neutrophils.
    Niggli V; Keller H
    Eur J Pharmacol; 1997 Sep; 335(1):43-52. PubMed ID: 9371545
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Increased breakdown of phosphatidylinositol 4,5-bisphosphate is not an initiating factor for actin assembly in human neutrophils.
    Bengtsson T; Rundquist I; Stendahl O; Wymann MP; Andersson T
    J Biol Chem; 1988 Nov; 263(33):17385-9. PubMed ID: 2846563
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Demethoxyviridin and wortmannin block phospholipase C and D activation in the human neutrophil.
    Bonser RW; Thompson NT; Randall RW; Tateson JE; Spacey GD; Hodson HF; Garland LG
    Br J Pharmacol; 1991 May; 103(1):1237-41. PubMed ID: 1908735
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Wortmannin inhibits insulin secretion in pancreatic islets and beta-TC3 cells independent of its inhibition of phosphatidylinositol 3-kinase.
    Gao Z; Konrad RJ; Collins H; Matschinsky FM; Rothenberg PL; Wolf BA
    Diabetes; 1996 Jul; 45(7):854-62. PubMed ID: 8666133
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Thrombin stimulates wortmannin-inhibitable phosphoinositide 3-kinase and membrane blebbing in CHRF-288 cells.
    Vemuri GS; Zhang J; Huang R; Keen JH; Rittenhouse SE
    Biochem J; 1996 Mar; 314 ( Pt 3)(Pt 3):805-10. PubMed ID: 8615773
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Initiation and maintenance of NGF-stimulated neurite outgrowth requires activation of a phosphoinositide 3-kinase.
    Jackson TR; Blader IJ; Hammonds-Odie LP; Burga CR; Cooke F; Hawkins PT; Wolf AG; Heldman KA; Theibert AB
    J Cell Sci; 1996 Feb; 109 ( Pt 2)(0 2):289-300. PubMed ID: 8838652
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phosphorylation of the platelet p47 phosphoprotein is mediated by the lipid products of phosphoinositide 3-kinase.
    Toker A; Bachelot C; Chen CS; Falck JR; Hartwig JH; Cantley LC; Kovacsovics TJ
    J Biol Chem; 1995 Dec; 270(49):29525-31. PubMed ID: 7493994
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.