BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

225 related articles for article (PubMed ID: 8258343)

  • 1. Human IgM+IgD+ B cells, the major B cell subset in the peripheral blood, express V kappa genes with no or little somatic mutation throughout life.
    Klein U; Küppers R; Rajewsky K
    Eur J Immunol; 1993 Dec; 23(12):3272-7. PubMed ID: 8258343
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Clonal analysis of a human antibody response. III. Nucleotide sequences of monoclonal IgM, IgG, and IgA to rabies virus reveal restricted V kappa gene utilization, junctional V kappa J kappa and V lambda J lambda diversity, and somatic hypermutation.
    Ikematsu W; Kobarg J; Ikematsu H; Ichiyoshi Y; Casali P
    J Immunol; 1998 Sep; 161(6):2895-905. PubMed ID: 9743351
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular single-cell analysis reveals that CD5-positive peripheral blood B cells in healthy humans are characterized by rearranged Vkappa genes lacking somatic mutation.
    Fischer M; Klein U; Küppers R
    J Clin Invest; 1997 Oct; 100(7):1667-76. PubMed ID: 9312164
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Evidence that the V kappa III gene usage is nonstochastic in both adult and newborn peripheral B cells and that peripheral CD5+ adult B cells are oligoclonal.
    Weber JC; Blaison G; Martin T; Knapp AM; Pasquali JL
    J Clin Invest; 1994 May; 93(5):2093-105. PubMed ID: 7514192
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The majority of human tonsillar CD5+ B cells express somatically mutated V kappa 4 genes.
    Ebeling SB; Schutte ME; Logtenberg T
    Eur J Immunol; 1993 Jun; 23(6):1405-8. PubMed ID: 7684690
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Variable region gene analysis of B cell subsets derived from a 4-year-old child: somatically mutated memory B cells accumulate in the peripheral blood already at young age.
    Klein U; Küppers R; Rajewsky K
    J Exp Med; 1994 Oct; 180(4):1383-93. PubMed ID: 7931072
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Peripheral human CD5+ and CD5- B cells may express somatically mutated VH5- and VH6-encoded IgM receptors.
    Ebeling SB; Schutte ME; Logtenberg T
    J Immunol; 1993 Dec; 151(12):6891-9. PubMed ID: 7505018
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Analysis of expressed V(H) genes in persistent polyclonal B cell lymphocytosis reveals absence of selection in CD27+IgM+IgD+ memory B cells.
    Loembé MM; Néron S; Delage R; Darveau A
    Eur J Immunol; 2002 Dec; 32(12):3678-88. PubMed ID: 12516560
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Human immunoglobulin (Ig)M+IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells.
    Klein U; Rajewsky K; Küppers R
    J Exp Med; 1998 Nov; 188(9):1679-89. PubMed ID: 9802980
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Monoclonal IgM rheumatoid factor secreted by CD5-negative B cells during mixed cryoglobulinemia. Evidence for somatic mutations and intraclonal diversity of the expressed VH region gene.
    Crouzier R; Martin T; Pasquali JL
    J Immunol; 1995 Jan; 154(1):413-21. PubMed ID: 7527818
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular Ig gene analysis reveals that monocytoid B cell lymphoma is a malignancy of mature B cells carrying somatically mutated V region genes and suggests that rearrangement of the kappa-deleting element (resulting in deletion of the Ig kappa enhancers) abolishes somatic hypermutation in the human.
    Küppers R; Hajadi M; Plank L; Rajewsky K; Hansmann ML
    Eur J Immunol; 1996 Aug; 26(8):1794-800. PubMed ID: 8765023
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nucleotidic sequence analysis of the variable domains of four human monoclonal IgM with an antibody activity to myelin-associated glycoprotein.
    Mariette X; Tsapis A; Brouet JC
    Eur J Immunol; 1993 Apr; 23(4):846-51. PubMed ID: 7681398
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Diffuse large cell lymphomas are derived from mature B cells carrying V region genes with a high load of somatic mutation and evidence of selection for antibody expression.
    Küppers R; Rajewsky K; Hansmann ML
    Eur J Immunol; 1997 Jun; 27(6):1398-405. PubMed ID: 9209491
    [TBL] [Abstract][Full Text] [Related]  

  • 14. High frequency of somatically mutated IgM molecules in the human adult blood B cell repertoire.
    van Es JH; Meyling FH; Logtenberg T
    Eur J Immunol; 1992 Oct; 22(10):2761-4. PubMed ID: 1396981
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The B lymphocyte in rheumatoid arthritis: analysis of rearranged V kappa genes from B cells infiltrating the synovial membrane.
    Gause A; Gundlach K; Zdichavsky M; Jacobs G; Koch B; Hopf T; Pfreundschuh M
    Eur J Immunol; 1995 Oct; 25(10):2775-82. PubMed ID: 7589071
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Diversity of immunoglobulin kappa light chain gene rearrangements and evidence for somatic mutation in V kappa IV family gene segments in X-linked agammaglobulinemia.
    Timmers E; Hermans MM; Kraakman ME; Hendriks RW; Schuurman RK
    Eur J Immunol; 1993 Mar; 23(3):619-24. PubMed ID: 8449210
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Memory B lymphocytes in human tonsil do not express surface IgD.
    Nicholson IC; Brisco MJ; Zola H
    J Immunol; 1995 Feb; 154(3):1105-13. PubMed ID: 7822787
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Expressed human immunoglobulin kappa genes and their hypermutation.
    Klein R; Jaenichen R; Zachau HG
    Eur J Immunol; 1993 Dec; 23(12):3248-62. PubMed ID: 8258341
    [TBL] [Abstract][Full Text] [Related]  

  • 19. IgVH gene analysis suggests that peritoneal B cells do not contribute to the gut immune system in man.
    Boursier L; Farstad IN; Mellembakken JR; Brandtzaeg P; Spencer J
    Eur J Immunol; 2002 Sep; 32(9):2427-36. PubMed ID: 12207327
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Limited junctional diversity in kappa light chains. Junctional sequences from CD43+B220+ early B cell progenitors resemble those from peripheral B cells.
    Victor KD; Vu K; Feeney AJ
    J Immunol; 1994 Apr; 152(7):3467-75. PubMed ID: 7511648
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.