BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

467 related articles for article (PubMed ID: 8264663)

  • 1. Dominant negative inhibition by mutant thyroid hormone receptors is thyroid hormone response element and receptor isoform specific.
    Zavacki AM; Harney JW; Brent GA; Larsen PR
    Mol Endocrinol; 1993 Oct; 7(10):1319-30. PubMed ID: 8264663
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Understanding the molecular mechanism of dominant negative action of mutant thyroid hormone beta 1-receptors: the important role of the wild-type/mutant receptor heterodimer.
    Zhu XG; Yu CL; McPhie P; Wong R; Cheng SY
    Endocrinology; 1996 Feb; 137(2):712-21. PubMed ID: 8593822
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Quantitative analysis of DNA binding affinity and dimerization properties of wild-type and mutant thyroid hormone receptor beta1.
    Takeda T; Nagasawa T; Miyamoto T; Minemura K; Hashizume K; Degroot LJ
    Thyroid; 2000 Jan; 10(1):11-8. PubMed ID: 10691308
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural features of thyroid hormone response elements that increase susceptibility to inhibition by an RTH mutant thyroid hormone receptor.
    Zavacki AM; Harney JW; Brent GA; Larsen PR
    Endocrinology; 1996 Jul; 137(7):2833-41. PubMed ID: 8770904
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Thyroid hormone receptor-beta mutants associated with generalized resistance to thyroid hormone show defects in their ligand-sensitive repression function.
    Piedrafita FJ; Ortiz MA; Pfahl M
    Mol Endocrinol; 1995 Nov; 9(11):1533-48. PubMed ID: 8584031
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interaction of human beta 1 thyroid hormone receptor and its mutants with DNA and retinoid X receptor beta. T3 response element-dependent dominant negative potency.
    Meier CA; Parkison C; Chen A; Ashizawa K; Meier-Heusler SC; Muchmore P; Cheng SY; Weintraub BD
    J Clin Invest; 1993 Oct; 92(4):1986-93. PubMed ID: 8408652
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Difference in dominant negative activities between mutant thyroid hormone receptors alpha1 and beta1 with an identical truncation in the extreme carboxyl-terminal tau4 domain.
    Nishiyama K; Andoh S; Kitahara A; Natsume H; Mikami T; Genma R; Nakamura H
    Mol Cell Endocrinol; 1998 Mar; 138(1-2):95-104. PubMed ID: 9685218
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Triiodothyroacetic acid has unique potential for therapy of resistance to thyroid hormone.
    Takeda T; Suzuki S; Liu RT; DeGroot LJ
    J Clin Endocrinol Metab; 1995 Jul; 80(7):2033-40. PubMed ID: 7608251
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differential sensitivity of thyroid hormone receptor isoform homodimers and mutant heterodimers to hormone-induced dissociation from deoxyribonucleic acid: its role in dominant negative action.
    Zhu XG; McPhie P; Cheng SY
    Endocrinology; 1997 Apr; 138(4):1456-63. PubMed ID: 9075702
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dominant negative transcriptional regulation by a mutant thyroid hormone receptor-beta in a family with generalized resistance to thyroid hormone.
    Sakurai A; Miyamoto T; Refetoff S; DeGroot LJ
    Mol Endocrinol; 1990 Dec; 4(12):1988-94. PubMed ID: 2082193
    [TBL] [Abstract][Full Text] [Related]  

  • 11. N-terminal variants of thyroid hormone receptor beta: differential function and potential contribution to syndrome of resistance to thyroid hormone.
    Ng L; Forrest D; Haugen BR; Wood WM; Curran T
    Mol Endocrinol; 1995 Sep; 9(9):1202-13. PubMed ID: 7491112
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evidence that phosphorylation events participate in thyroid hormone action.
    Jones KE; Brubaker JH; Chin WW
    Endocrinology; 1994 Feb; 134(2):543-8. PubMed ID: 8299553
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cell type-dependent modulation of the dominant negative action of human mutant thyroid hormone beta 1 receptors.
    Wong R; Zhu XG; Pineda MA; Cheng SY; Weintraub BD
    Mol Med; 1995 Mar; 1(3):306-19. PubMed ID: 8529109
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The function of retinoid X receptors on negative thyroid hormone response elements.
    Takeda T; Nagasawa T; Miyamoto T; Hashizume K; DeGroot LJ
    Mol Cell Endocrinol; 1997 Apr; 128(1-2):85-96. PubMed ID: 9140079
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vitro transcriptional studies of the roles of the thyroid hormone (T3) response elements and minimal promoters in T3-stimulated gene transcription.
    Suen CS; Yen PM; Chin WW
    J Biol Chem; 1994 Jan; 269(2):1314-22. PubMed ID: 8288596
    [TBL] [Abstract][Full Text] [Related]  

  • 16. New insights on the mechanism(s) of the dominant negative effect of mutant thyroid hormone receptor in generalized resistance to thyroid hormone.
    Yen PM; Sugawara A; Refetoff S; Chin WW
    J Clin Invest; 1992 Nov; 90(5):1825-31. PubMed ID: 1430208
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Variable transcriptional activity and ligand binding of mutant beta 1 3,5,3'-triiodothyronine receptors from four families with generalized resistance to thyroid hormone.
    Meier CA; Dickstein BM; Ashizawa K; McClaskey JH; Muchmore P; Ransom SC; Menke JB; Hao EH; Usala SJ; Bercu BB
    Mol Endocrinol; 1992 Feb; 6(2):248-58. PubMed ID: 1569968
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Isoform variable action among thyroid hormone receptor mutants provides insight into pituitary resistance to thyroid hormone.
    Safer JD; Langlois MF; Cohen R; Monden T; John-Hope D; Madura J; Hollenberg AN; Wondisford FE
    Mol Endocrinol; 1997 Jan; 11(1):16-26. PubMed ID: 8994184
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Amino acid substitutions of thyroid hormone receptor-beta at codon 435 with resistance to thyroid hormone selectively alter homodimer formation.
    Nomura Y; Nagaya T; Tsukaguchi H; Takamatsu J; Seo H
    Endocrinology; 1996 Oct; 137(10):4082-6. PubMed ID: 8828460
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dominant negative and DNA-binding properties of mutant thyroid hormone receptors that are defective in homodimerization but not heterodimerization.
    Kitajima K; Nagaya T; Jameson JL
    Thyroid; 1995 Oct; 5(5):343-53. PubMed ID: 8563470
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.