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26. Structure-based design of inhibitors of purine nucleoside phosphorylase. 1. 9-(arylmethyl) derivatives of 9-deazaguanine. Montgomery JA; Niwas S; Rose JD; Secrist JA; Babu YS; Bugg CE; Erion MD; Guida WC; Ealick SE J Med Chem; 1993 Jan; 36(1):55-69. PubMed ID: 8421291 [TBL] [Abstract][Full Text] [Related]
27. Pharmacokinetics and pharmacodynamics of peldesine (BCX-34), a purine nucleoside phosphorylase inhibitor, following single and multiple oral doses in healthy volunteers. Viegas TX; Omura GA; Stoltz RR; Kisicki J J Clin Pharmacol; 2000 Apr; 40(4):410-20. PubMed ID: 10761169 [TBL] [Abstract][Full Text] [Related]
28. Effect of 9-benzyl-9-deazaguanine, a potent inhibitor of purine nucleoside phosphorylase, on the cytotoxicity and metabolism of 6-thio-2'-deoxyguanosine. Parker WB; Allan PW; Niwas S; Montgomery JA; Bennett LL Cancer Res; 1994 Apr; 54(7):1742-5. PubMed ID: 8137289 [TBL] [Abstract][Full Text] [Related]
29. Mechanisms of deoxyguanosine lymphotoxicity. Human thymocytes, but not peripheral blood lymphocytes accumulate deoxy-GTP in conditions simulating purine nucleoside phosphorylase deficiency. Fairbanks LD; Taddeo A; Duley JA; Simmonds HA J Immunol; 1990 Jan; 144(2):485-91. PubMed ID: 2104895 [TBL] [Abstract][Full Text] [Related]
30. Nucleosides. 5. Synthesis of guanine and formycin B derivatives as potential inhibitors of purine nucleoside phosphorylase. Chern JW; Lee HY; Chen CS; Shewach DS; Daddona PE; Townsend LB J Med Chem; 1993 Apr; 36(8):1024-31. PubMed ID: 8478902 [TBL] [Abstract][Full Text] [Related]
31. Pharmacokinetics/pharmacodynamics of CI-1000, a purine nucleoside phosphorylase (PNP) inhibitor, in rats and monkeys. Hallak H; Hayes A; Dong M; Gilbertsen R; Guttendorf R Adv Exp Med Biol; 1994; 370():161-5. PubMed ID: 7660882 [No Abstract] [Full Text] [Related]
33. 8-Aminoguanine Induces Diuresis, Natriuresis, and Glucosuria by Inhibiting Purine Nucleoside Phosphorylase and Reduces Potassium Excretion by Inhibiting Rac1. Jackson EK; Mi Z; Kleyman TR; Cheng D J Am Heart Assoc; 2018 Nov; 7(21):e010085. PubMed ID: 30608204 [TBL] [Abstract][Full Text] [Related]
34. Inhibitors of purine nucleoside phosphorylase, C(8) and C(5') substitutions. Stoeckler JD; Cambor C; Kuhns V; Chu SH; Parks RE Biochem Pharmacol; 1982 Jan; 31(2):163-71. PubMed ID: 6800381 [No Abstract] [Full Text] [Related]
35. Purine nucleoside phosphorylase as a cytosolic arsenate reductase. Gregus Z; Németi B Toxicol Sci; 2002 Nov; 70(1):13-9. PubMed ID: 12388830 [TBL] [Abstract][Full Text] [Related]
36. Fluorescence studies of calf spleen purine nucleoside phosphorylase (PNP) complexes with guanine and 9-deazaguanine. Stepniak K; Zinić B; Wierzchowski J; Bzowska A Nucleosides Nucleotides Nucleic Acids; 2007; 26(6-7):841-7. PubMed ID: 18066911 [TBL] [Abstract][Full Text] [Related]
37. Differential cytotoxicity of deoxyguanosine and 8-aminoguanosine for human leukemic cell lines and normal bone marrow progenitor cells. de Fouw NJ; Ma DD; Michalevicz R; Gray DA; Hoffbrand AV Hematol Oncol; 1984; 2(2):189-97. PubMed ID: 6430777 [TBL] [Abstract][Full Text] [Related]
38. The mechanism of inhibition and "reversal" of mitogen-induced lymphocyte activation in a model of purine-nucleoside phosphorylase deficiency. Albert D; Bluestein HG; Willis RC; Nette K; Seegmiller JE Cell Immunol; 1984 Jul; 86(2):501-9. PubMed ID: 6428752 [TBL] [Abstract][Full Text] [Related]
39. The effect of deoxyguanosine on human lymphocyte function. I. Analysis of the interference with lymphocyte proliferation in vitro. Spaapen LJ; Rijkers GT; Staal GE; Rijksen G; Wadman SK; Stoop JW; Zegers BJ J Immunol; 1984 May; 132(5):2311-7. PubMed ID: 6425399 [TBL] [Abstract][Full Text] [Related]
40. Synthesis and biological evaluation of 9-deazaguanine derivatives connected by a linker to difluoromethylene phosphonic acid as multi-substrate analogue inhibitors of PNP. Hikishima S; Hashimoto M; Magnowska L; Bzowska A; Yokomatsu T Bioorg Med Chem Lett; 2007 Aug; 17(15):4173-7. PubMed ID: 17544667 [TBL] [Abstract][Full Text] [Related] [Previous] [Next] [New Search]