121 related articles for article (PubMed ID: 8274516)
1. Antitumor activities of a cephalosporin prodrug in combination with monoclonal antibody-beta-lactamase conjugates.
Vrudhula VM; Svensson HP; Kennedy KA; Senter PD; Wallace PM
Bioconjug Chem; 1993; 4(5):334-40. PubMed ID: 8274516
[TBL] [Abstract][Full Text] [Related]
2. Monoclonal antibody-beta-lactamase conjugates for the activation of a cephalosporin mustard prodrug.
Svensson HP; Kadow JF; Vrudhula VM; Wallace PM; Senter PD
Bioconjug Chem; 1992; 3(2):176-81. PubMed ID: 1515470
[TBL] [Abstract][Full Text] [Related]
3. Therapeutic effects of monoclonal antibody-beta-lactamase conjugates in combination with a nitrogen mustard anticancer prodrug in models of human renal cell carcinoma.
Svensson HP; Frank IS; Berry KK; Senter PD
J Med Chem; 1998 Apr; 41(9):1507-12. PubMed ID: 9554883
[TBL] [Abstract][Full Text] [Related]
4. Cephalosporin derivatives of doxorubicin as prodrugs for activation by monoclonal antibody-beta-lactamase conjugates.
Vrudhula VM; Svensson HP; Senter PD
J Med Chem; 1995 Apr; 38(8):1380-5. PubMed ID: 7731023
[TBL] [Abstract][Full Text] [Related]
5. Regressions and cures of melanoma xenografts following treatment with monoclonal antibody beta-lactamase conjugates in combination with anticancer prodrugs.
Kerr DE; Schreiber GJ; Vrudhula VM; Svensson HP; Hellström I; Hellström KE; Senter PD
Cancer Res; 1995 Aug; 55(16):3558-63. PubMed ID: 7627964
[TBL] [Abstract][Full Text] [Related]
6. Immunologically specific activation of a cephalosporin derivative of mitomycin C by monoclonal antibody beta-lactamase conjugates.
Vrudhula VM; Svensson HP; Senter PD
J Med Chem; 1997 Aug; 40(17):2788-92. PubMed ID: 9276025
[TBL] [Abstract][Full Text] [Related]
7. In vitro and in vivo activities of a doxorubicin prodrug in combination with monoclonal antibody beta-lactamase conjugates.
Svensson HP; Vrudhula VM; Emswiler JE; MacMaster JF; Cosand WL; Senter PD; Wallace PM
Cancer Res; 1995 Jun; 55(11):2357-65. PubMed ID: 7757987
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and characterization of monoclonal antibody-beta-lactamase conjugates.
Svensson HP; Wallace PM; Senter PD
Bioconjug Chem; 1994; 5(3):262-7. PubMed ID: 7918745
[TBL] [Abstract][Full Text] [Related]
9. Comparison of recombinant and synthetically formed monoclonal antibody-beta-lactamase conjugates for anticancer prodrug activation.
Kerr DE; Vrudhula VM; Svensson HP; Siemers NO; Senter PD
Bioconjug Chem; 1999; 10(6):1084-9. PubMed ID: 10563779
[TBL] [Abstract][Full Text] [Related]
10. Construction, expression, and activities of L49-sFv-beta-lactamase, a single-chain antibody fusion protein for anticancer prodrug activation.
Siemers NO; Kerr DE; Yarnold S; Stebbins MR; Vrudhula VM; Hellström I; Hellström KE; Senter PD
Bioconjug Chem; 1997; 8(4):510-9. PubMed ID: 9258449
[TBL] [Abstract][Full Text] [Related]
11. Development and activities of a new melphalan prodrug designed for tumor-selective activation.
Kerr DE; Li Z; Siemers NO; Senter PD; Vrudhula VM
Bioconjug Chem; 1998; 9(2):255-9. PubMed ID: 9548542
[TBL] [Abstract][Full Text] [Related]
12. Design and synthesis of a beta-lactamase activated 5-fluorouracil prodrug.
Phelan RM; Ostermeier M; Townsend CA
Bioorg Med Chem Lett; 2009 Feb; 19(4):1261-3. PubMed ID: 19167216
[TBL] [Abstract][Full Text] [Related]
13. In vitro and in vivo activities of monoclonal antibody-alkaline phosphatase conjugates in combination with phenol mustard phosphate.
Wallace PM; Senter PD
Bioconjug Chem; 1991; 2(5):349-52. PubMed ID: 1790175
[TBL] [Abstract][Full Text] [Related]
14. Poly(ethylene glycol)-doxorubicin conjugates containing beta-lactamase-sensitive linkers.
Senter PD; Svensson HP; Schreiber GJ; Rodriguez JL; Vrudhula VM
Bioconjug Chem; 1995; 6(4):389-94. PubMed ID: 7578358
[TBL] [Abstract][Full Text] [Related]
15. Cephalosporin prodrugs of paclitaxel for immunologically specific activation by L-49-sFv-beta-lactamase fusion protein.
Vrudhula VM; Kerr DE; Siemers NO; Dubowchik GM; Senter PD
Bioorg Med Chem Lett; 2003 Feb; 13(3):539-42. PubMed ID: 12565967
[TBL] [Abstract][Full Text] [Related]
16. Genetic construction, expression, and characterization of a single chain anti-carcinoma antibody fused to beta-lactamase.
Goshorn SC; Svensson HP; Kerr DE; Somerville JE; Senter PD; Fell HP
Cancer Res; 1993 May; 53(9):2123-7. PubMed ID: 8481914
[TBL] [Abstract][Full Text] [Related]
17. Prodrugs of doxorubicin and melphalan and their activation by a monoclonal antibody-penicillin-G amidase conjugate.
Vrudhula VM; Senter PD; Fischer KJ; Wallace PM
J Med Chem; 1993 Apr; 36(7):919-23. PubMed ID: 8464046
[TBL] [Abstract][Full Text] [Related]
18. Design, synthesis, and biological evaluation of a cephalosporin-monohydroguaiaretic acid prodrug activated by a monoclonal antibody-beta-lactamase conjugate.
Hakimelahi GH; Shia KS; Pasdar M; Hakimelahi S; Khalafi-Nezhad A; Soltani MN; Mei NW; Mei HC; Saboury AA; Rezaei-Tavirani M; Moosavi-Movahedi AA
Bioorg Med Chem; 2002 Sep; 10(9):2927-32. PubMed ID: 12110314
[TBL] [Abstract][Full Text] [Related]
19. Selective activation of anticancer prodrugs by monoclonal antibody-enzyme conjugates.
Wallace PM; Senter PD
Methods Find Exp Clin Pharmacol; 1994 Sep; 16(7):505-12. PubMed ID: 7885077
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and cytotoxic activity of a glucuronylated prodrug of nornitrogen mustard.
Papot S; Combaud D; Bosslet K; Gerken M; Czech J; Gesson JP
Bioorg Med Chem Lett; 2000 Aug; 10(16):1835-7. PubMed ID: 10969980
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]