BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

64 related articles for article (PubMed ID: 8275088)

  • 1. Nonsense mutations in the C-terminal SH2 region of the GTPase activating protein (GAP) gene in human tumours.
    Friedman E; Gejman PV; Martin GA; McCormick F
    Nat Genet; 1993 Nov; 5(3):242-7. PubMed ID: 8275088
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural analysis of the Ras GTPase activating protein catalytic domain by semirandom mutagenesis: implications for a mechanism of interaction with Ras-GTP.
    Hettich L; Marshall M
    Cancer Res; 1994 Oct; 54(20):5438-44. PubMed ID: 7923177
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The non-catalytic domain of ras-GAP inhibits transformation induced by G protein coupled receptors.
    Xu N; McCormick F; Gutkind JS
    Oncogene; 1994 Feb; 9(2):597-601. PubMed ID: 8290270
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of a mouse orthologue of the human ras-GAP-SH3-domain binding protein and structural confirmation that these proteins contain an RNA recognition motif.
    Kennedy D; Wood SA; Ramsdale T; Tam PP; Steiner KA; Mattick JS
    Biomed Pept Proteins Nucleic Acids; 1996-1997; 2(3):93-9. PubMed ID: 9575347
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Crystal structure of the GTPase-activating domain of human p120GAP and implications for the interaction with Ras.
    Scheffzek K; Lautwein A; Kabsch W; Ahmadian MR; Wittinghofer A
    Nature; 1996 Dec; 384(6609):591-6. PubMed ID: 8955277
    [TBL] [Abstract][Full Text] [Related]  

  • 6. cDNA cloning and chromosomal mapping of a novel human GAP (GAP1M), a GTPase-activating protein of Ras.
    Li S; Satoh H; Watanabe T; Nakamura S; Hattori S
    Genomics; 1996 Aug; 35(3):625-7. PubMed ID: 8812506
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Functional interactions between isolated SH2 domains and insulin/Ras signaling pathways of Xenopus oocytes: opposite effects of the carboxy- and amino-terminal SH2 domains of p85 PI 3-kinase.
    Aroca P; Mahadevan D; Santos E
    Oncogene; 1996 Nov; 13(9):1839-46. PubMed ID: 8934529
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Induced direct binding of the adapter protein Nck to the GTPase-activating protein-associated protein p62 by epidermal growth factor.
    Tang J; Feng GS; Li W
    Oncogene; 1997 Oct; 15(15):1823-32. PubMed ID: 9362449
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A functional assay for heterozygous mutations in the GTPase activating protein related domain of the neurofibromatosis type 1 gene.
    Ishioka C; Ballester R; Engelstein M; Vidal M; Kassel J; The I; Bernards A; Gusella JF; Friend SH
    Oncogene; 1995 Mar; 10(5):841-7. PubMed ID: 7898926
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A putative effector of Ral has homology to Rho/Rac GTPase activating proteins.
    Park SH; Weinberg RA
    Oncogene; 1995 Dec; 11(11):2349-55. PubMed ID: 8570186
    [TBL] [Abstract][Full Text] [Related]  

  • 11. N-terminal sequences contained in the Src homology 2 and 3 domains of p120 GTPase-activating protein are required for full catalytic activity toward Ras.
    Bryant SS; Mitchell AL; Collins F; Miao W; Marshall M; Jove R
    J Biol Chem; 1996 Mar; 271(9):5195-9. PubMed ID: 8617802
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Upregulation of the RAS-GTPase activating protein (GAP)-binding protein (G3BP) in proliferating RPE cells.
    Kociok N; Esser P; Unfried K; Parker F; Schraermeyer U; Grisanti S; Toqué B; Heimann K
    J Cell Biochem; 1999 Aug; 74(2):194-201. PubMed ID: 10404389
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ras-GTPase activating protein inhibition specifically induces apoptosis of tumour cells.
    Leblanc V; Delumeau I; Tocqué B
    Oncogene; 1999 Aug; 18(34):4884-9. PubMed ID: 10490822
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Oligophrenin-1 encodes a rhoGAP protein involved in X-linked mental retardation.
    Billuart P; Bienvenu T; Ronce N; des Portes V; Vinet MC; Zemni R; Roest Crollius H; Carrié A; Fauchereau F; Cherry M; Briault S; Hamel B; Fryns JP; Beldjord C; Kahn A; Moraine C; Chelly J
    Nature; 1998 Apr; 392(6679):923-6. PubMed ID: 9582072
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Linear free energy relationships in the intrinsic and GTPase activating protein-stimulated guanosine 5'-triphosphate hydrolysis of p21ras.
    Schweins T; Geyer M; Kalbitzer HR; Wittinghofer A; Warshel A
    Biochemistry; 1996 Nov; 35(45):14225-31. PubMed ID: 8916907
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lrg1p functions as a putative GTPase-activating protein in the Pkc1p-mediated cell integrity pathway in Saccharomyces cerevisiae.
    Lorberg A; Schmitz HP; Jacoby JJ; Heinisch JJ
    Mol Genet Genomics; 2001 Nov; 266(3):514-26. PubMed ID: 11713681
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Genetic analysis of the catalytic domain of the GAP gene in human lung cancer cell lines.
    Mitsudomi T; Friedman E; Gejman PV; McCormick F; Gazdar AF
    Hum Genet; 1994 Jan; 93(1):27-31. PubMed ID: 8270251
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The guanine triphosphatase (GTPase) activating protein (GAP)-related domain of the neurofibromatosis type 1 gene is not mutated in neural crest-derived sporadic tumours.
    Murgia A; Anglani F; Vinanzi C; Polli R; Basso G; Perilongo G; Giangaspero F; Zacchello F
    Eur J Cancer; 1998 Mar; 34(4):577-9. PubMed ID: 9713312
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cerebellar beta 2-chimaerin, a GTPase-activating protein for p21 ras-related rac is specifically expressed in granule cells and has a unique N-terminal SH2 domain.
    Leung T; How BE; Manser E; Lim L
    J Biol Chem; 1994 Apr; 269(17):12888-92. PubMed ID: 8175705
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural differences in the minimal catalytic domains of the GTPase-activating proteins p120GAP and neurofibromin.
    Ahmadian MR; Wiesmüller L; Lautwein A; Bischoff FR; Wittinghofer A
    J Biol Chem; 1996 Jul; 271(27):16409-15. PubMed ID: 8663212
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.