163 related articles for article (PubMed ID: 8276119)
1. Structure of partially-activated E. coli heat-labile enterotoxin (LT) at 2.6 A resolution.
Merritt EA; Pronk SE; Sixma TK; Kalk KH; van Zanten BA; Hol WG
FEBS Lett; 1994 Jan; 337(1):88-92. PubMed ID: 8276119
[TBL] [Abstract][Full Text] [Related]
2. Crystal structure of a new heat-labile enterotoxin, LT-IIb.
van den Akker F; Sarfaty S; Twiddy EM; Connell TD; Holmes RK; Hol WG
Structure; 1996 Jun; 4(6):665-78. PubMed ID: 8805549
[TBL] [Abstract][Full Text] [Related]
3. Crystal structure of heat-labile enterotoxin from Escherichia coli with increased thermostability introduced by an engineered disulfide bond in the A subunit.
van den Akker F; Feil IK; Roach C; Platas AA; Merritt EA; Hol WG
Protein Sci; 1997 Dec; 6(12):2644-9. PubMed ID: 9416616
[TBL] [Abstract][Full Text] [Related]
4. Role of trypsin-like cleavage at arginine 192 in the enzymatic and cytotonic activities of Escherichia coli heat-labile enterotoxin.
Grant CC; Messer RJ; Cieplak W
Infect Immun; 1994 Oct; 62(10):4270-8. PubMed ID: 7927684
[TBL] [Abstract][Full Text] [Related]
5. Heat-labile enterotoxin crystal forms with variable A/B5 orientation. Analysis of conformational flexibility.
Sixma TK; Aguirre A; Terwisscha van Scheltinga AC; Wartna ES; Kalk KH; Hol WG
FEBS Lett; 1992 Jun; 305(2):81-5. PubMed ID: 1618345
[TBL] [Abstract][Full Text] [Related]
6. Crystal structure of a cholera toxin-related heat-labile enterotoxin from E. coli.
Sixma TK; Pronk SE; Kalk KH; Wartna ES; van Zanten BA; Witholt B; Hol WG
Nature; 1991 May; 351(6325):371-7. PubMed ID: 2034287
[TBL] [Abstract][Full Text] [Related]
7. A pH-dependent conformational change in the B-subunit pentamer of Escherichia coli heat-labile enterotoxin: structural basis and possible functional role for a conserved feature of the AB5 toxin family.
Ruddock LW; Webb HM; Ruston SP; Cheesman C; Freedman RB; Hirst TR
Biochemistry; 1996 Dec; 35(50):16069-76. PubMed ID: 8973177
[TBL] [Abstract][Full Text] [Related]
8. Comparison of the B-pentamers of heat-labile enterotoxin and verotoxin-1: two structures with remarkable similarity and dissimilarity.
Sixma TK; Stein PE; Hol WG; Read RJ
Biochemistry; 1993 Jan; 32(1):191-8. PubMed ID: 8418837
[TBL] [Abstract][Full Text] [Related]
9. Contribution of the disulfide bond of the A subunit to the action of Escherichia coli heat-labile enterotoxin.
Okamoto K; Nomura T; Fujii Y; Yamanaka H
J Bacteriol; 1998 Mar; 180(6):1368-74. PubMed ID: 9515902
[TBL] [Abstract][Full Text] [Related]
10. The Arg7Lys mutant of heat-labile enterotoxin exhibits great flexibility of active site loop 47-56 of the A subunit.
van den Akker F; Merritt EA; Pizza M; Domenighini M; Rappuoli R; Hol WG
Biochemistry; 1995 Sep; 34(35):10996-1004. PubMed ID: 7669757
[TBL] [Abstract][Full Text] [Related]
11. Structure-based discovery of a pore-binding ligand: towards assembly inhibitors for cholera and related AB5 toxins.
Hovey BT; Verlinde CL; Merritt EA; Hol WG
J Mol Biol; 1999 Jan; 285(3):1169-78. PubMed ID: 9887271
[TBL] [Abstract][Full Text] [Related]
12. Refined structure of Escherichia coli heat-labile enterotoxin, a close relative of cholera toxin.
Sixma TK; Kalk KH; van Zanten BA; Dauter Z; Kingma J; Witholt B; Hol WG
J Mol Biol; 1993 Apr; 230(3):890-918. PubMed ID: 8478941
[TBL] [Abstract][Full Text] [Related]
13. Structural foundation for the design of receptor antagonists targeting Escherichia coli heat-labile enterotoxin.
Merritt EA; Sarfaty S; Feil IK; Hol WG
Structure; 1997 Nov; 5(11):1485-99. PubMed ID: 9384564
[TBL] [Abstract][Full Text] [Related]
14. Galactose-binding site in Escherichia coli heat-labile enterotoxin (LT) and cholera toxin (CT).
Merritt EA; Sixma TK; Kalk KH; van Zanten BA; Hol WG
Mol Microbiol; 1994 Aug; 13(4):745-53. PubMed ID: 7997185
[TBL] [Abstract][Full Text] [Related]
15. Mutation of a buried residue causes loss of activity but no conformational change in the heat-labile enterotoxin of Escherichia coli.
Merritt EA; Sarfaty S; Pizza M; Domenighini M; Rappuoli R; Hol WG
Nat Struct Biol; 1995 Apr; 2(4):269-72. PubMed ID: 7796260
[No Abstract] [Full Text] [Related]
16. Intermolecular interactions between the A and B subunits of heat-labile enterotoxin from Escherichia coli promote holotoxin assembly and stability in vivo.
Streatfield SJ; Sandkvist M; Sixma TK; Bagdasarian M; Hol WG; Hirst TR
Proc Natl Acad Sci U S A; 1992 Dec; 89(24):12140-4. PubMed ID: 1465452
[TBL] [Abstract][Full Text] [Related]
17. Crystal structure of a non-toxic mutant of heat-labile enterotoxin, which is a potent mucosal adjuvant.
van den Akker F; Pizza M; Rappuoli R; Hol WG
Protein Sci; 1997 Dec; 6(12):2650-4. PubMed ID: 9416617
[TBL] [Abstract][Full Text] [Related]
18. Exploration of the GM1 receptor-binding site of heat-labile enterotoxin and cholera toxin by phenyl-ring-containing galactose derivatives.
Fan E; Merritt EA; Zhang Z; Pickens JC; Roach C; Ahn M; Hol WG
Acta Crystallogr D Biol Crystallogr; 2001 Feb; 57(Pt 2):201-12. PubMed ID: 11173465
[TBL] [Abstract][Full Text] [Related]
19. Effect of site-directed mutagenic alterations on ADP-ribosyltransferase activity of the A subunit of Escherichia coli heat-labile enterotoxin.
Lobet Y; Cluff CW; Cieplak W
Infect Immun; 1991 Sep; 59(9):2870-9. PubMed ID: 1908825
[TBL] [Abstract][Full Text] [Related]
20. Crystal structures of an intrinsically active cholera toxin mutant yield insight into the toxin activation mechanism.
O'Neal CJ; Amaya EI; Jobling MG; Holmes RK; Hol WG
Biochemistry; 2004 Apr; 43(13):3772-82. PubMed ID: 15049684
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
