BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

169 related articles for article (PubMed ID: 8286011)

  • 1. Synthesis and biological evaluation of phenanthrene-derived carboxamides as cytotoxic agents.
    Cherubim P; Deady LW; Dorkos M; Quazi NH; Baguley BC; Denny WA
    Anticancer Drug Des; 1993 Dec; 8(6):429-38. PubMed ID: 8286011
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-activity relationships for substituted bis(acridine-4-carboxamides): a new class of anticancer agents.
    Gamage SA; Spicer JA; Atwell GJ; Finlay GJ; Baguley BC; Denny WA
    J Med Chem; 1999 Jul; 42(13):2383-93. PubMed ID: 10395479
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Comparative biodistribution and metabolism of carbon-11-labeled N-[2-(dimethylamino)ethyl]acridine-4-carboxamide and DNA-intercalating analogues.
    Osman S; Rowlinson-Busza G; Luthra SK; Aboagye EO; Brown GD; Brady F; Myers R; Gamage SA; Denny WA; Baguley BC; Price PM
    Cancer Res; 2001 Apr; 61(7):2935-44. PubMed ID: 11306471
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Rational design, synthesis, and biological evaluation of bis(pyrimido[5,6,1-de]acridines) and bis(pyrazolo[3,4,5-kl]acridine-5-carboxamides) as new anticancer agents.
    Antonini I; Polucci P; Magnano A; Sparapani S; Martelli S
    J Med Chem; 2004 Oct; 47(21):5244-50. PubMed ID: 15456268
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dimeric analogues of non-cationic tricyclic aromatic carboxamides are a new class of cytotoxic agents.
    Spicer JA; Gamage SA; Atwell GJ; Finlay GJ; Baguley BC; Denny WA
    Anticancer Drug Des; 1999 Jun; 14(3):281-9. PubMed ID: 10500503
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-activity relationships for acridine-substituted analogues of the mixed topoisomerase I/II inhibitor N-[2-(dimethylamino)ethyl]acridine-4-carboxamide.
    Spicer JA; Gamage SA; Atwell GJ; Finlay GJ; Baguley BC; Denny WA
    J Med Chem; 1997 Jun; 40(12):1919-29. PubMed ID: 9191970
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis, and biological properties of new bis(acridine-4-carboxamides) as anticancer agents.
    Antonini I; Polucci P; Magnano A; Gatto B; Palumbo M; Menta E; Pescalli N; Martelli S
    J Med Chem; 2003 Jul; 46(14):3109-15. PubMed ID: 12825949
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and antitumor properties of N-[2-(dimethylamino)ethyl]carboxamide derivatives of fused tetracyclic quinolines and quinoxalines: a new class of putative topoisomerase inhibitors.
    Deady LW; Kaye AJ; Finlay GJ; Baguley BC; Denny WA
    J Med Chem; 1997 Jun; 40(13):2040-6. PubMed ID: 9207945
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pyrimidoacridine derivatives as potential antitumor agents.
    Antonini I; Cola D; Martelli S; Cholody WM; Konopa J
    Farmaco; 1992; 47(7-8):1035-46. PubMed ID: 1445611
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Isoquino[4,5-bc]acridines: design, synthesis and evaluation of DNA binding, anti-tumor and DNA photo-damaging ability.
    Yang P; Yang Q; Qian X; Tong L; Li X
    J Photochem Photobiol B; 2006 Sep; 84(3):221-6. PubMed ID: 16714120
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 5,7-Disubstituted analogues of the mixed topoisomerase I/II poison N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA): DNA binding and patterns of cytotoxicity.
    Spicer JA; Finlay GJ; Baguley BC; Velea L; Graves DE; Denny WA
    Anticancer Drug Des; 1999 Feb; 14(1):37-45. PubMed ID: 10363026
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and biological evaluation of modified acridines: the effect of N- and O- substituent in the nitrogenated ring on antitumor activity.
    Sánchez I; Reches R; Caignard DH; Renard P; Pujol MD
    Eur J Med Chem; 2006 Mar; 41(3):340-52. PubMed ID: 16413635
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Topoisomerase I/II selectivity among derivatives of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA).
    Bridewell DJ; Finlay GJ; Baguley BC
    Anticancer Drug Des; 2001 Dec; 16(6):317-24. PubMed ID: 12375884
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 2,3-Dihydro-1H,7H-pyrimido[5,6,1-de]acridine-1,3,7-trione derivatives, a class of cytotoxic agents active on multidrug-resistant cell lines: synthesis, biological evaluation, and structure-activity relationships.
    Antonini I; Polucci P; Kelland LR; Menta E; Pescalli N; Martelli S
    J Med Chem; 1999 Jul; 42(14):2535-41. PubMed ID: 10411474
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 1-[(omega-aminoalkyl)amino]-4-[N-(omega-aminoalkyl)carbamoyl]-9-oxo-9, 10-dihydroacridines as intercalating cytotoxic agents: synthesis, DNA binding, and biological evaluation.
    Antonini I; Polucci P; Jenkins TC; Kelland LR; Menta E; Pescalli N; Stefanska B; Mazerski J; Martelli S
    J Med Chem; 1997 Nov; 40(23):3749-55. PubMed ID: 9371240
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and cytotoxic activity of carboxamide derivatives of benzo[b][1,6]naphthyridines.
    Deady LW; Rodemann T; Zhuang L; Baguley BC; Denny WA
    J Med Chem; 2003 Mar; 46(6):1049-54. PubMed ID: 12620081
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cellular uptake of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA).
    Haldane A; Finlay GJ; Hay MP; Denny WA; Baguley BC
    Anticancer Drug Des; 1999 Jun; 14(3):275-80. PubMed ID: 10500502
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cytotoxic and DNA binding properties of aminoalkyl derivatives of di- and triazaphenanthrenes.
    Argiropoulos G; Bates MR; Cherubim P; Deady LW; Ganakas AM; Baguley BC; Denny WA
    Anticancer Drug Des; 1992 Aug; 7(4):285-96. PubMed ID: 1510798
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacological and toxicological aspects of new imidazoacridinone antitumor agents.
    Berger B; Marquardt H; Westendorf J
    Cancer Res; 1996 May; 56(9):2094-104. PubMed ID: 8616856
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DNA-directed alkylating agents. 5. Acridinecarboxamide derivatives of (1,2-diaminoethane)dichloroplatinum(II).
    Lee HH; Palmer BD; Baguley BC; Chin M; McFadyen WD; Wickham G; Thorsbourne-Palmer D; Wakelin LP; Denny WA
    J Med Chem; 1992 Aug; 35(16):2983-7. PubMed ID: 1501223
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.