BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

813 related articles for article (PubMed ID: 8291057)

  • 1. Construction of Syrian hamster lines congenic at the polymorphic acetyltransferase locus (NAT2): acetylator genotype-dependent N- and O-acetylation of arylamine carcinogens.
    Hein DW; Doll MA; Rustan TD; Gray K; Ferguson RJ; Feng Y
    Toxicol Appl Pharmacol; 1994 Jan; 124(1):16-24. PubMed ID: 8291057
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolic activation of N-hydroxy-2-aminofluorene and N-hydroxy-2-acetylaminofluorene by monomorphic N-acetyltransferase (NAT1) and polymorphic N-acetyltransferase (NAT2) in colon cytosols of Syrian hamsters congenic at the NAT2 locus.
    Hein DW; Doll MA; Gray K; Rustan TD; Ferguson RJ
    Cancer Res; 1993 Feb; 53(3):509-14. PubMed ID: 8425184
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Polymorphic and monomorphic expression of arylamine carcinogen N-acetyltransferase isozymes in tumor target organ cytosols of Syrian hamsters congenic at the polymorphic acetyltransferase locus.
    Hein DW; Rustan TD; Bucher KD; Miller LS
    J Pharmacol Exp Ther; 1991 Nov; 259(2):699-704. PubMed ID: 1941618
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Purification of hepatic polymorphic arylamine N-acetyltransferase from homozygous rapid acetylator inbred hamster: identity with polymorphic N-hydroxyarylamine-O-acetyltransferase.
    Trinidad A; Hein DW; Rustan TD; Ferguson RJ; Miller LS; Bucher KD; Kirlin WG; Ogolla F; Andrews AF
    Cancer Res; 1990 Dec; 50(24):7942-9. PubMed ID: 2253236
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Acetylator genotype-dependent expression of arylamine N-acetyltransferase and N-hydroxyarylamine O-acetyltransferase in Syrian inbred hamster intestine and colon. Identity with the hepatic acetylation polymorphism.
    Ogolla F; Ferguson RJ; Kirlin WG; Trinidad A; Andrews AF; Mpezo M; Hein DW
    Drug Metab Dispos; 1990; 18(5):680-5. PubMed ID: 1981720
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification and kinetic characterization of acetylator genotype-dependent and -independent arylamine carcinogen N-acetyltransferases in hamster bladder cytosol.
    Yerokun T; Kirlin WG; Trinidad A; Ferguson RJ; Ogolla F; Andrews AF; Brady PK; Hein DW
    Drug Metab Dispos; 1989; 17(3):231-7. PubMed ID: 2568902
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Extrahepatic expression of N-acetylator genotype in the inbred hamster.
    Hein DW; Kirlin WG; Ogolla F; Trinidad A
    Drug Metab Dispos; 1987; 15(1):68-73. PubMed ID: 2881761
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Kinetic characterization of acetylator genotype-dependent and -independent N-acetyltransferase isozymes in homozygous rapid and slow acetylator inbred hamster liver cytosol.
    Trinidad A; Kirlin WG; Ogolla F; Andrews AF; Yerokun T; Ferguson RJ; Brady PK; Hein DW
    Drug Metab Dispos; 1989; 17(3):238-47. PubMed ID: 2568903
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Acetylator genotype-dependent formation of 2-aminofluorene-hemoglobin adducts in rapid and slow acetylator Syrian hamsters congenic at the NAT2 locus.
    Feng Y; Rustan TD; Ferguson RJ; Doll MA; Hein DW
    Toxicol Appl Pharmacol; 1994 Jan; 124(1):10-5. PubMed ID: 8291051
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Acetylator genotype-dependent metabolic activation of carcinogenic N-hydroxyarylamines by S-acetyl coenzyme A-dependent enzymes of inbred hamster tissue cytosols: relationship to arylamine N-acetyltransferase.
    Hein DW; Flammang TJ; Kirlin WG; Trinidad A; Ogolla F
    Carcinogenesis; 1987 Dec; 8(12):1767-74. PubMed ID: 3677303
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Syrian hamster monomorphic N-acetyltransferase (NAT1) alleles: amplification, cloning, sequencing, and expression in E. coli.
    Ferguson RJ; Doll MA; Rustan TD; Baumstark BR; Hein DW
    Pharmacogenetics; 1994 Apr; 4(2):82-90. PubMed ID: 8081415
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Genetic control of acetyl coenzyme A-dependent arylamine N-acetyltransferase, hydrazine N-acetyltransferase, and N-hydroxy-arylamine O-acetyltransferase enzymes in C57BL/6J, A/J, AC57F1, and the rapid and slow acetylator A.B6 and B6.A congenic inbred mouse.
    Hein DW; Trinidad A; Yerokun T; Ferguson RJ; Kirlin WG; Weber WW
    Drug Metab Dispos; 1988; 16(3):341-7. PubMed ID: 2900723
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Polymorphic expression of acetyl coenzyme A-dependent arylamine N-acetyltransferase and acetyl coenzyme A-dependent O-acetyltransferase-mediated activation of N-hydroxyarylamines by human bladder cytosol.
    Kirlin WG; Trinidad A; Yerokun T; Ogolla F; Ferguson RJ; Andrews AF; Brady PK; Hein DW
    Cancer Res; 1989 May; 49(9):2448-54. PubMed ID: 2784998
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cloning, sequencing, and recombinant expression of NAT1, NAT2, and NAT3 derived from the C3H/HeJ (rapid) and A/HeJ (slow) acetylator inbred mouse: functional characterization of the activation and deactivation of aromatic amine carcinogens.
    Fretland AJ; Doll MA; Gray K; Feng Y; Hein DW
    Toxicol Appl Pharmacol; 1997 Feb; 142(2):360-6. PubMed ID: 9070359
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Monomorphic and polymorphic human arylamine N-acetyltransferases: a comparison of liver isozymes and expressed products of two cloned genes.
    Grant DM; Blum M; Beer M; Meyer UA
    Mol Pharmacol; 1991 Feb; 39(2):184-91. PubMed ID: 1996083
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Acetylator genotype (NAT2)-dependent formation of aberrant crypts in congenic Syrian hamsters administered 3,2'-dimethyl-4-aminobiphenyl.
    Feng Y; Wagner RJ; Fretland AJ; Becker WK; Cooley AM; Pretlow TP; Lee KJ; Hein DW
    Cancer Res; 1996 Feb; 56(3):527-31. PubMed ID: 8564966
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cloning, expression, and functional characterization of rapid and slow acetylator polymorphic N-acetyl-transferase encoding genes of the Syrian hamster.
    Ferguson RJ; Doll MA; Rustan TD; Hein DW
    Pharmacogenetics; 1996 Feb; 6(1):55-66. PubMed ID: 8845861
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The role of acetylator genotype on hepatic and extrahepatic acetylation, deacetylation, and sulfation of 2-aminofluorene, 2-acetylaminofluorene, and N-hydroxy-2-acetylaminofluorene in the inbred hamster.
    Hein DW; Kirlin WG; Ogolla F; Trinidad A; Thompson LK; Ferguson RJ
    Drug Metab Dispos; 1986; 14(5):566-73. PubMed ID: 2876863
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Extrahepatic expression of the N-acetylation polymorphism toward arylamine carcinogens in tumor target organs of an inbred rat model.
    Hein DW; Rustan TD; Bucher KD; Furman EJ; Martin WJ
    J Pharmacol Exp Ther; 1991 Jul; 258(1):232-6. PubMed ID: 2072298
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Metabolic activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Syrian hamsters congenic at the N-acetyltransferase 2 (NAT2) locus.
    Fretland AJ; Devanaboyina US; Doll MA; Zhao S; Xiao GH; Hein DW
    Toxicol Sci; 2003 Aug; 74(2):253-9. PubMed ID: 12773763
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 41.