BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

179 related articles for article (PubMed ID: 8293548)

  • 21. Evidence for oxidative metabolism in the genotoxicity of the atmospheric reaction product 2-nitronaphthalene in human lymphoblastoid cell lines.
    Sasaki JC; Arey J; Eastmond DA; Parks KK; Phousongphouang PT; Grosovsky AJ
    Mutat Res; 1999 Sep; 445(1):113-25. PubMed ID: 10521697
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Catalytic role of cytochrome P4502B6 in the N-demethylation of S-mephenytoin.
    Heyn H; White RB; Stevens JC
    Drug Metab Dispos; 1996 Sep; 24(9):948-54. PubMed ID: 8886603
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Development of a human lymphoblastoid cell line constitutively expressing human CYP1A1 cDNA: substrate specificity with model substrates and promutagens.
    Penman BW; Chen L; Gelboin HV; Gonzalez FJ; Crespi CL
    Carcinogenesis; 1994 Sep; 15(9):1931-7. PubMed ID: 7923587
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Human reductive halothane metabolism in vitro is catalyzed by cytochrome P450 2A6 and 3A4.
    Spracklin DK; Thummel KE; Kharasch ED
    Drug Metab Dispos; 1996 Sep; 24(9):976-83. PubMed ID: 8886607
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Evaluation of pyrrolizidine alkaloid-induced genotoxicity using metabolically competent TK6 cell lines.
    Li X; He X; Chen S; Guo X; Bryant MS; Guo L; Manjanatha MG; Zhou T; Witt KL; Mei N
    Food Chem Toxicol; 2020 Nov; 145():111662. PubMed ID: 32798647
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Oxidation of butadiene monoxide to meso- and (+/-)-diepoxybutane by cDNA-expressed human cytochrome P450s and by mouse, rat, and human liver microsomes: evidence for preferential hydration of meso-diepoxybutane in rat and human liver microsomes.
    Krause RJ; Elfarra AA
    Arch Biochem Biophys; 1997 Jan; 337(2):176-84. PubMed ID: 9016811
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Role of human microsomal and human complementary DNA-expressed cytochromes P4501A2 and P4503A4 in the bioactivation of aflatoxin B1.
    Gallagher EP; Wienkers LC; Stapleton PL; Kunze KL; Eaton DL
    Cancer Res; 1994 Jan; 54(1):101-8. PubMed ID: 8261428
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Biotransformation of parathion in human liver: participation of CYP3A4 and its inactivation during microsomal parathion oxidation.
    Butler AM; Murray M
    J Pharmacol Exp Ther; 1997 Feb; 280(2):966-73. PubMed ID: 9023313
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Evaluation of the potential health effects of the atmospheric reaction products of polycyclic aromatic hydrocarbons.
    Grosovsky AJ; Sasaki JC; Arey J; Eastmond DA; Parks KK; Atkinson R
    Res Rep Health Eff Inst; 1999 Mar; (84):i-iv, 1-22; discussion 23-7. PubMed ID: 10319378
    [TBL] [Abstract][Full Text] [Related]  

  • 30. CYP2D6 catalyzes tamoxifen 4-hydroxylation in human liver.
    Dehal SS; Kupfer D
    Cancer Res; 1997 Aug; 57(16):3402-6. PubMed ID: 9270005
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Human liver microsomes are efficient catalysts of 1,3-butadiene oxidation: evidence for major roles by cytochromes P450 2A6 and 2E1.
    Duescher RJ; Elfarra AA
    Arch Biochem Biophys; 1994 Jun; 311(2):342-9. PubMed ID: 8203896
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Genotoxic potential of tamoxifen and analogues in female Fischer F344/n rats, DBA/2 and C57BL/6 mice and in human MCL-5 cells.
    White IN; de Matteis F; Davies A; Smith LL; Crofton-Sleigh C; Venitt S; Hewer A; Phillips DH
    Carcinogenesis; 1992 Dec; 13(12):2197-203. PubMed ID: 1473224
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Characterization of the human cytochrome P450 forms involved in metabolism of tamoxifen to its alpha-hydroxy and alpha,4-dihydroxy derivatives.
    Notley LM; Crewe KH; Taylor PJ; Lennard MS; Gillam EM
    Chem Res Toxicol; 2005 Oct; 18(10):1611-8. PubMed ID: 16533026
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Oxidation of 1,2-epoxy-3-butene to 1,2:3,4-diepoxybutane by cDNA-expressed human cytochromes P450 2E1 and 3A4 and human, mouse and rat liver microsomes.
    Seaton MJ; Follansbee MH; Bond JA
    Carcinogenesis; 1995 Oct; 16(10):2287-93. PubMed ID: 7586124
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Toxicity of antiestrogens.
    Hirsimäki P; Aaltonen A; Mäntylä E
    Breast J; 2002; 8(2):92-6. PubMed ID: 11896754
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Development of a human lymphoblastoid cell line constitutively expressing human CYP1B1 cDNA: substrate specificity with model substrates and promutagens.
    Crespi CL; Penman BW; Steimel DT; Smith T; Yang CS; Sutter TR
    Mutagenesis; 1997 Mar; 12(2):83-9. PubMed ID: 9106248
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Development and Application of TK6-derived Cells Expressing Human Cytochrome P450s for Genotoxicity Testing.
    Li X; Chen S; Guo X; Wu Q; Seo JE; Guo L; Manjanatha MG; Zhou T; Witt KL; Mei N
    Toxicol Sci; 2020 Jun; 175(2):251-265. PubMed ID: 32159784
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Specificity of cDNA-expressed human and rodent cytochrome P450s in the oxidative metabolism of the potent carcinogen 7,12-dimethylbenz[a]anthracene.
    Shou M; Korzekwa KR; Krausz KW; Buters JT; Grogan J; Goldfarb I; Hardwick JP; Gonzalez FJ; Gelboin HV
    Mol Carcinog; 1996 Dec; 17(4):241-9. PubMed ID: 8989918
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Oxidation of tamoxifen by human flavin-containing monooxygenase (FMO) 1 and FMO3 to tamoxifen-N-oxide and its novel reduction back to tamoxifen by human cytochromes P450 and hemoglobin.
    Parte P; Kupfer D
    Drug Metab Dispos; 2005 Oct; 33(10):1446-52. PubMed ID: 15987777
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Comparison of the effects of tamoxifen and toremifene on rat hepatocarcinogenesis.
    Kärki A; Mäntylä E; Hirsimäki Y; Karlsson S; Toikkanen S; Hirsimäki P
    Arch Toxicol; 2000 Jul; 74(4-5):249-56. PubMed ID: 10959800
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.