BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1647 related articles for article (PubMed ID: 8299427)

  • 1. Cell transformation by ras and regulation of its protein product.
    Lowy DR; Johnson MR; DeClue JE; Cen H; Zhang K; Papageorge AG; Vass WC; Willumsen BM; Valentine MB; Look AT
    Ciba Found Symp; 1993; 176():67-80; discussion 80-4. PubMed ID: 8299427
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inactivation of the NF1 gene in human melanoma and neuroblastoma cell lines without impaired regulation of GTP.Ras.
    Johnson MR; Look AT; DeClue JE; Valentine MB; Lowy DR
    Proc Natl Acad Sci U S A; 1993 Jun; 90(12):5539-43. PubMed ID: 8516298
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A conserved alternative splice in the von Recklinghausen neurofibromatosis (NF1) gene produces two neurofibromin isoforms, both of which have GTPase-activating protein activity.
    Andersen LB; Ballester R; Marchuk DA; Chang E; Gutmann DH; Saulino AM; Camonis J; Wigler M; Collins FS
    Mol Cell Biol; 1993 Jan; 13(1):487-95. PubMed ID: 8417346
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ras effector loop mutations that dissociate p120GAP and neurofibromin interactions.
    Stang S; Bottorff D; Stone JC
    Mol Carcinog; 1996 Jan; 15(1):64-9. PubMed ID: 8561868
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Suppression of oncogenic Ras by mutant neurofibromatosis type 1 genes with single amino acid substitutions.
    Nakafuku M; Nagamine M; Ohtoshi A; Tanaka K; Toh-e A; Kaziro Y
    Proc Natl Acad Sci U S A; 1993 Jul; 90(14):6706-10. PubMed ID: 8341688
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [Heterogeneity of GTPase-activating proteins for Ras in the regulation of Ras signal transduction pathway].
    Hattori S; Baba H
    Yakugaku Zasshi; 1996 Jan; 116(1):21-38. PubMed ID: 8699317
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Neurofibromin can inhibit Ras-dependent growth by a mechanism independent of its GTPase-accelerating function.
    Johnson MR; DeClue JE; Felzmann S; Vass WC; Xu G; White R; Lowy DR
    Mol Cell Biol; 1994 Jan; 14(1):641-5. PubMed ID: 8264632
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Kinetics of interaction between normal and proline 12 Ras and the GTPase-activating proteins, p120-GAP and neurofibromin. The significance of the intrinsic GTPase rate in determining the transforming ability of ras.
    Eccleston JF; Moore KJ; Morgan L; Skinner RH; Lowe PN
    J Biol Chem; 1993 Dec; 268(36):27012-9. PubMed ID: 8262937
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients.
    Basu TN; Gutmann DH; Fletcher JA; Glover TW; Collins FS; Downward J
    Nature; 1992 Apr; 356(6371):713-5. PubMed ID: 1570015
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differential regulation of cellular activities by GTPase-activating protein and NF1.
    al-Alawi N; Xu G; White R; Clark R; McCormick F; Feramisco JR
    Mol Cell Biol; 1993 Apr; 13(4):2497-503. PubMed ID: 8455625
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Schwann cells from neurofibromin deficient mice exhibit activation of p21ras, inhibition of cell proliferation and morphological changes.
    Kim HA; Rosenbaum T; Marchionni MA; Ratner N; DeClue JE
    Oncogene; 1995 Jul; 11(2):325-35. PubMed ID: 7624147
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ras-interacting domain of Ral GDP dissociation stimulator like (RGL) reverses v-Ras-induced transformation and Raf-1 activation in NIH3T3 cells.
    Okazaki M; Kishida S; Murai H; Hinoi T; Kikuchi A
    Cancer Res; 1996 May; 56(10):2387-92. PubMed ID: 8625316
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanistic aspects of signaling through Ras in NIH 3T3 cells.
    Zhang K; Papageorge AG; Lowy DR
    Science; 1992 Jul; 257(5070):671-4. PubMed ID: 1496380
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Farnesyltransferase inhibitors block the neurofibromatosis type I (NF1) malignant phenotype.
    Yan N; Ricca C; Fletcher J; Glover T; Seizinger BR; Manne V
    Cancer Res; 1995 Aug; 55(16):3569-75. PubMed ID: 7627966
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of Ras-GAP and the neurofibromatosis-1 gene product by eicosanoids.
    Han JW; McCormick F; Macara IG
    Science; 1991 Apr; 252(5005):576-9. PubMed ID: 1902323
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bcr encodes a GTPase-activating protein for p21rac.
    Diekmann D; Brill S; Garrett MD; Totty N; Hsuan J; Monfries C; Hall C; Lim L; Hall A
    Nature; 1991 May; 351(6325):400-2. PubMed ID: 1903516
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Peptides containing a consensus Ras binding sequence from Raf-1 and theGTPase activating protein NF1 inhibit Ras function.
    Clark GJ; Drugan JK; Terrell RS; Bradham C; Der CJ; Bell RM; Campbell S
    Proc Natl Acad Sci U S A; 1996 Feb; 93(4):1577-81. PubMed ID: 8643674
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae.
    Xu GF; Lin B; Tanaka K; Dunn D; Wood D; Gesteland R; White R; Weiss R; Tamanoi F
    Cell; 1990 Nov; 63(4):835-41. PubMed ID: 2121369
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel, activated RAS mutations alter protein-protein interactions.
    Dalley BK; Cannon JF
    Oncogene; 1996 Sep; 13(6):1209-20. PubMed ID: 8808695
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ras in signal transduction.
    Satoh T; Kaziro Y
    Semin Cancer Biol; 1992 Aug; 3(4):169-77. PubMed ID: 1421161
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 83.