These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

136 related articles for article (PubMed ID: 8304171)

  • 1. Thermodynamic study of folate analogue binding to dihydrofolate reductases from different species.
    Sasso S; Gilli R; Lopez C; Sari JC; Briand C
    Adv Exp Med Biol; 1993; 338():521-4. PubMed ID: 8304171
    [No Abstract]   [Full Text] [Related]  

  • 2. Comparative thermodynamic study of the interaction of some antifolates with dihydrofolate reductase.
    Gilli RM; Sari JC; Lopez CL; Rimet OS; Briand CM
    Biochim Biophys Acta; 1990 Sep; 1040(2):245-50. PubMed ID: 2400775
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structures of dihydrofolate reductase-thymidylate synthase of Trypanosoma cruzi in the folate-free state and in complex with two antifolate drugs, trimetrexate and methotrexate.
    Senkovich O; Schormann N; Chattopadhyay D
    Acta Crystallogr D Biol Crystallogr; 2009 Jul; 65(Pt 7):704-16. PubMed ID: 19564691
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Light activates reduction of methotrexate by NADPH in the ternary complex with Escherichia coli dihydrofolate reductase.
    Chen YQ; Gulotta M; Cheung HT; Callender R
    Photochem Photobiol; 1999 Jan; 69(1):77-85. PubMed ID: 10063803
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Thermal denaturation of bacterial and bovine dihydrofolate reductases and their complexes with NADPH, trimethoprim and methotrexate.
    Sasso S; Protasevich I; Gilli R; Makarov A; Briand C
    J Biomol Struct Dyn; 1995 Apr; 12(5):1023-32. PubMed ID: 7626237
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural Insights into Mycobacterium tuberculosis Rv2671 Protein as a Dihydrofolate Reductase Functional Analogue Contributing to para-Aminosalicylic Acid Resistance.
    Cheng YS; Sacchettini JC
    Biochemistry; 2016 Feb; 55(7):1107-19. PubMed ID: 26848874
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Methotrexate binding to dihydrofolate reductase from a methotrexate-resistant strain of Escherichia coli.
    Williams MN; Poe M; Greenfield NJ; Hirshfield JM; Hoogsteen K
    J Biol Chem; 1973 Sep; 248(18):6375-9. PubMed ID: 4147159
    [No Abstract]   [Full Text] [Related]  

  • 8. Activity of antifolates against Pneumocystis carinii dihydrofolate reductase and identification of a potent new agent.
    Allegra CJ; Kovacs JA; Drake JC; Swan JC; Chabner BA; Masur H
    J Exp Med; 1987 Mar; 165(3):926-31. PubMed ID: 2950200
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interaction of methotrexate, folates, and pyridine nucleotides with dihydrofolate reductase: calorimetric and spectroscopic binding studies.
    Subramanian S; Kaufman BT
    Proc Natl Acad Sci U S A; 1978 Jul; 75(7):3201-5. PubMed ID: 28523
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanism of inhibition of dihydrofolate reductases from bacterial and vertebrate sources by various classes of folate analogues.
    Stone SR; Morrison JF
    Biochim Biophys Acta; 1986 Feb; 869(3):275-85. PubMed ID: 3511964
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nonadditivity of mutational effects at the folate binding site of Escherichia coli dihydrofolate reductase.
    Huang Z; Wagner CR; Benkovic SJ
    Biochemistry; 1994 Sep; 33(38):11576-85. PubMed ID: 7918371
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dynamics of trimethoprim bound to dihydrofolate reductase--a deuterium NMR study.
    Yang QX; Huang FY; Lin TH; Gelbaum L; Howell EE; Huang TH
    Solid State Nucl Magn Reson; 1996 Dec; 7(3):193-201. PubMed ID: 9050157
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Increased substrate affinity in the Escherichia coli L28R dihydrofolate reductase mutant causes trimethoprim resistance.
    Abdizadeh H; Tamer YT; Acar O; Toprak E; Atilgan AR; Atilgan C
    Phys Chem Chem Phys; 2017 May; 19(18):11416-11428. PubMed ID: 28422217
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Kinetics of substrate, coenzyme, and inhibitor binding to Escherichia coli dihydrofolate reductase.
    Cayley PJ; Dunn SM; King RW
    Biochemistry; 1981 Feb; 20(4):874-9. PubMed ID: 7011378
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Thermodynamic study of the influence of NADPH on the binding of methotrexate and its metabolites to a mammalian dihydrofolate reductase.
    Gilli RM; Sari JC; Sica LM; Briand CM
    Biochim Biophys Acta; 1988 Jan; 964(1):53-60. PubMed ID: 3334873
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dynamic dysfunction in dihydrofolate reductase results from antifolate drug binding: modulation of dynamics within a structural state.
    Mauldin RV; Carroll MJ; Lee AL
    Structure; 2009 Mar; 17(3):386-94. PubMed ID: 19278653
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Reduction of Folate by Dihydrofolate Reductase from Thermotoga maritima.
    Loveridge EJ; Hroch L; Hughes RL; Williams T; Davies RL; Angelastro A; Luk LY; Maglia G; Allemann RK
    Biochemistry; 2017 Apr; 56(13):1879-1886. PubMed ID: 28319664
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Thermodynamic study of dihydrofolate reductase inhibitor selectivity.
    Sasso SP; Gilli RM; Sari JC; Rimet OS; Briand CM
    Biochim Biophys Acta; 1994 Jul; 1207(1):74-9. PubMed ID: 8043612
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Computational predictions of binding affinities to dihydrofolate reductase: synthesis and biological evaluation of methotrexate analogues.
    Graffner-Nordberg M; Marelius J; Ohlsson S; Persson A; Swedberg G; Andersson P; Andersson SE; Aqvist J; Hallberg A
    J Med Chem; 2000 Oct; 43(21):3852-61. PubMed ID: 11052790
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Calorimetric studies of ligand binding in R67 dihydrofolate reductase.
    Jackson M; Chopra S; Smiley RD; Maynord PO; Rosowsky A; London RE; Levy L; Kalman TI; Howell EE
    Biochemistry; 2005 Sep; 44(37):12420-33. PubMed ID: 16156655
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.