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6. Mutations of human dihydrofolate reductase causing decreased inhibition by methotrexate. Blakley RL; Appleman JR; Chunduru SK; Nakano T; Lewis WS; Harris SE Adv Exp Med Biol; 1993; 338():473-9. PubMed ID: 8304162 [No Abstract] [Full Text] [Related]
7. Methotrexate-insensitive mutants of human dihydrofolate reductase (hDHFR) constructed by site-directed mutagenesis at phenylalanine 34. Nakano T; Appleman JR; Blakley RL Adv Exp Med Biol; 1993; 338():503-5. PubMed ID: 8304167 [No Abstract] [Full Text] [Related]
8. Characterization and comparative studies of zebrafish and human recombinant dihydrofolate reductases--inhibition by folic acid and polyphenols. Kao TT; Wang KC; Chang WN; Lin CY; Chen BH; Wu HL; Shi GY; Tsai JN; Fu TF Drug Metab Dispos; 2008 Mar; 36(3):508-16. PubMed ID: 18056255 [TBL] [Abstract][Full Text] [Related]
9. Isolation and characterization of a variant dihydrofolate reductase cDNA from methotrexate-resistant murine L5178Y cells. McIvor RS; Simonsen CC Nucleic Acids Res; 1990 Dec; 18(23):7025-32. PubMed ID: 2263462 [TBL] [Abstract][Full Text] [Related]
10. Effect of codon 22 mutations on substrate and inhibitor binding for human dihydrofolate reductase. Ercikan E; Waltham M; Dicker A; Schweitzer B; Bertino JR Adv Exp Med Biol; 1993; 338():515-9. PubMed ID: 8304170 [No Abstract] [Full Text] [Related]
12. Methotrexate-resistant Chinese hamster ovary cells have amplified a 135-kilobase-pair region that includes the dihydrofolate reductase gene. Milbrandt JD; Heintz NH; White WC; Rothman SM; Hamlin JL Proc Natl Acad Sci U S A; 1981 Oct; 78(10):6043-7. PubMed ID: 6273843 [TBL] [Abstract][Full Text] [Related]
13. Differential alterations of dihydrofolate reductase gene in human leukemia cell lines made resistant to various folate analogues. Miyachi H; Takemura Y; Kobayashi H; Ando K; Ando Y Jpn J Cancer Res; 1993 Jan; 84(1):9-12. PubMed ID: 8449831 [TBL] [Abstract][Full Text] [Related]
14. Kinetic investigation of methotrexate resistant human dihydrofolate reductase (hDHFR) mutants at Phe31. Chunduru SK; Appleman JR; Blakley RL Adv Exp Med Biol; 1993; 338():507-10. PubMed ID: 8304168 [No Abstract] [Full Text] [Related]
15. Cells exposed to antifolates show increased cellular levels of proteins fused to dihydrofolate reductase: a method to modulate gene expression. Mayer-Kuckuk P; Banerjee D; Malhotra S; Doubrovin M; Iwamoto M; Akhurst T; Balatoni J; Bornmann W; Finn R; Larson S; Fong Y; Gelovani Tjuvajev J; Blasberg R; Bertino JR Proc Natl Acad Sci U S A; 2002 Mar; 99(6):3400-5. PubMed ID: 11891321 [TBL] [Abstract][Full Text] [Related]
16. Amplified dihydrofolate reductase genes are localized to a homogeneously staining region of a single chromosome in a methotrexate-resistant Chinese hamster ovary cell line. Nunberg JH; Kaufman RJ; Schimke RT; Urlaub G; Chasin LA Proc Natl Acad Sci U S A; 1978 Nov; 75(11):5553-6. PubMed ID: 281704 [TBL] [Abstract][Full Text] [Related]
18. Expression of murine dihydrofolate reductase complementary DNA in oocytes of Xenopus laevis. Itoh N; Mori K; Toga K; Ikegami S Int J Biochem; 1991; 23(4):491-7. PubMed ID: 2015958 [TBL] [Abstract][Full Text] [Related]
19. Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells. Alt FW; Kellems RE; Bertino JR; Schimke RT J Biol Chem; 1978 Mar; 253(5):1357-70. PubMed ID: 627542 [No Abstract] [Full Text] [Related]
20. Detection of a single base mutation in the human dihydrofolate reductase gene from a methotrexate-resistant cell line using the polymerase chain reaction. Dicker AP; Volkenandt M; Bertino JR Cancer Commun; 1989; 1(1):7-12. PubMed ID: 2640157 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]