These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

121 related articles for article (PubMed ID: 8304929)

  • 1. Induction of rat liver GSH transferases by 1,2-dithiole-3-thione illustrates both anticarcinogenic and tumor-promoting properties.
    Meyer DJ; Coles B; Harris J; Gilmore KS; Raney K; Harris TM; Guengerich FP; Kensler TW; Ketterer B
    Basic Life Sci; 1993; 61():171-9. PubMed ID: 8304929
    [No Abstract]   [Full Text] [Related]  

  • 2. Potent inhibition of aflatoxin-induced hepatic tumorigenesis by the monofunctional enzyme inducer 1,2-dithiole-3-thione.
    Kensler TW; Groopman JD; Eaton DL; Curphey TJ; Roebuck BD
    Carcinogenesis; 1992 Jan; 13(1):95-100. PubMed ID: 1346373
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of phase 2 enzyme induction in chemoprotection by dithiolethiones.
    Kwak MK; Egner PA; Dolan PM; Ramos-Gomez M; Groopman JD; Itoh K; Yamamoto M; Kensler TW
    Mutat Res; 2001 Sep; 480-481():305-15. PubMed ID: 11506823
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Quantitation of tissue- and sex-specific induction of rat GSH transferase subunits by dietary 1,2-dithiole-3-thiones.
    Meyer DJ; Harris JM; Gilmore KS; Coles B; Kensler TW; Ketterer B
    Carcinogenesis; 1993 Apr; 14(4):567-72. PubMed ID: 8472316
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Indole-3-carbinol induces a rat liver glutathione transferase subunit (Yc2) with high activity toward aflatoxin B1 exo-epoxide. Association with reduced levels of hepatic aflatoxin-DNA adducts in vivo.
    Stresser DM; Williams DE; McLellan LI; Harris TM; Bailey GS
    Drug Metab Dispos; 1994; 22(3):392-9. PubMed ID: 8070315
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-activity relationships in the induction of Phase II enzymes by derivatives of 3H-1,2-dithiole-3-thione in rats.
    Munday R; Zhang Y; Munday CM; Li J
    Chem Biol Interact; 2006 Mar; 160(2):115-22. PubMed ID: 16458871
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Induction of cellular glutathione and glutathione S-transferase by 3H-1,2-dithiole-3-thione in rat aortic smooth muscle A10 cells: protection against acrolein-induced toxicity.
    Cao Z; Hardej D; Trombetta LD; Trush MA; Li Y
    Atherosclerosis; 2003 Feb; 166(2):291-301. PubMed ID: 12535742
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Induced expression of drug metabolizing enzymes by preventive agents: role of the antioxidant response element.
    Lubet RA; Yao R; Grubbs CJ; You M; Wang Y
    Chem Biol Interact; 2009 Nov; 182(1):22-8. PubMed ID: 19695238
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of aflatoxin B1-metabolizing aldehyde reductase and glutathione S-transferase by chemoprotectors.
    McLellan LI; Judah DJ; Neal GE; Hayes JD
    Biochem J; 1994 May; 300 ( Pt 1)(Pt 1):117-24. PubMed ID: 8198522
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanism of protection against aflatoxin tumorigenicity in rats fed 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (oltipraz) and related 1,2-dithiol-3-thiones and 1,2-dithiol-3-ones.
    Kensler TW; Egner PA; Dolan PM; Groopman JD; Roebuck BD
    Cancer Res; 1987 Aug; 47(16):4271-7. PubMed ID: 2886217
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular dosimetry of urinary aflatoxin-N7-guanine and serum aflatoxin-albumin adducts predicts chemoprotection by 1,2-dithiole-3-thione in rats.
    Groopman JD; DeMatos P; Egner PA; Love-Hunt A; Kensler TW
    Carcinogenesis; 1992 Jan; 13(1):101-6. PubMed ID: 1733561
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Oltipraz-mediated changes in aflatoxin B(1) biotransformation in rat liver: implications for human chemointervention.
    Buetler TM; Bammler TK; Hayes JD; Eaton DL
    Cancer Res; 1996 May; 56(10):2306-13. PubMed ID: 8625305
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Evidence for thiol-dependent production of oxygen radicals by 4-methyl-5-pyrazinyl-3H-1,2-dithiole-3-thione (oltipraz) and 3H-1,2-dithiole-3-thione: possible relevance to the anticarcinogenic properties of 1,2-dithiole-3-thiones.
    Kim W; Gates KS
    Chem Res Toxicol; 1997 Mar; 10(3):296-301. PubMed ID: 9084909
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dimethiole-3-thione.
    Kwak MK; Itoh K; Yamamoto M; Sutter TR; Kensler TW
    Mol Med; 2001 Feb; 7(2):135-45. PubMed ID: 11471548
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 1,2-dithiole-3-thione and its structural analogue oltipraz are potent inhibitors of dibenz.
    Smith WA; Arif JM; Gupta RC
    Int J Cancer; 2001 Jan; 91(1):132-6. PubMed ID: 11149412
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Intermittent dosing with oltipraz: relationship between chemoprevention of aflatoxin-induced tumorigenesis and induction of glutathione S-transferases.
    Primiano T; Egner PA; Sutter TR; Kelloff GJ; Roebuck BD; Kensler TW
    Cancer Res; 1995 Oct; 55(19):4319-24. PubMed ID: 7671242
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Metabolism of aflatoxin B1 by human hepatocytes in primary culture.
    Langouet S; Coles B; Morel F; Maheo K; Ketterer B; Guillouzo A
    Adv Exp Med Biol; 1996; 387():439-42. PubMed ID: 8794238
    [No Abstract]   [Full Text] [Related]  

  • 18. Hepatic glutathione S-transferases in mice fed on a diet containing the anticarcinogenic antioxidant butylated hydroxyanisole. Isolation of mouse glutathione S-transferase heterodimers by gradient elution of the glutathione-Sepharose affinity matrix.
    Hayes JD; Kerr LA; Peacock SD; Cronshaw AD; McLellan LI
    Biochem J; 1991 Jul; 277 ( Pt 2)(Pt 2):501-12. PubMed ID: 1859377
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Patterns of DNA adduct formation in liver and mammary epithelial cells of rats treated with 7,12-dimethylbenz(a)anthracene, and selective effects of chemopreventive agents.
    Izzotti A; Camoirano A; Cartiglia C; Grubbs CJ; Lubet RA; Kelloff GJ; De Flora S
    Cancer Res; 1999 Sep; 59(17):4285-90. PubMed ID: 10485473
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation of rat glutamate-cysteine ligase (gamma-glutamylcysteine synthetase) subunits by chemopreventive agents and in aflatoxin B(1)-induced preneoplasia.
    Shepherd AG; Manson MM; Ball HW; McLellan LI
    Carcinogenesis; 2000 Oct; 21(10):1827-34. PubMed ID: 11023540
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.