BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

763 related articles for article (PubMed ID: 8325965)

  • 1. Progesterone 16 alpha-hydroxylase activity is catalyzed by human cytochrome P450 17 alpha-hydroxylase.
    Swart P; Swart AC; Waterman MR; Estabrook RW; Mason JI
    J Clin Endocrinol Metab; 1993 Jul; 77(1):98-102. PubMed ID: 8325965
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Steroid 17 alpha-hydroxylase and 17,20-lyase activities of P450c17: contributions of serine106 and P450 reductase.
    Lin D; Black SM; Nagahama Y; Miller WL
    Endocrinology; 1993 Jun; 132(6):2498-506. PubMed ID: 8504753
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of the adrenal cytochrome P450C17 in the hamster, a small animal model for the study of adrenal dehydroepiandrosterone biosynthesis.
    Cloutier M; Fleury A; Courtemanche J; Ducharme L; Mason JI; Lehoux JG
    DNA Cell Biol; 1997 Mar; 16(3):357-68. PubMed ID: 9115645
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The 17, 20-lyase activity of cytochrome p450c17 from human fetal testis favors the delta5 steroidogenic pathway.
    Flück CE; Miller WL; Auchus RJ
    J Clin Endocrinol Metab; 2003 Aug; 88(8):3762-6. PubMed ID: 12915666
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Progesterone and testosterone hydroxylation by cytochromes P450 2C19, 2C9, and 3A4 in human liver microsomes.
    Yamazaki H; Shimada T
    Arch Biochem Biophys; 1997 Oct; 346(1):161-9. PubMed ID: 9328296
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The role of cytochrome b5 in the biosynthesis of androgens by human P450c17.
    Katagiri M; Kagawa N; Waterman MR
    Arch Biochem Biophys; 1995 Mar; 317(2):343-7. PubMed ID: 7893148
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ketoconazole inhibition of the bifunctional cytochrome P450c17 does not affect androgen formation from the endogenous lyase substrate. The catalytic site remains refractory in the course of intermediary hydroxyprogesterone processing.
    Kühn-Velten WN; Lessmann M
    Biochem Pharmacol; 1992 Dec; 44(12):2371-8. PubMed ID: 1472102
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Expression of bovine 17 alpha-hydroxylase cytochrome P-450 cDNA in nonsteroidogenic (COS 1) cells.
    Zuber MX; Simpson ER; Waterman MR
    Science; 1986 Dec; 234(4781):1258-61. PubMed ID: 3535074
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Progesterone metabolism in hepatic microsomes. Effect of the cytochrome P-450 inhibitor, ketoconazole, and the NADPH 5 alpha-reductase inhibitor, 4-MA, upon the metabolic profile in human, monkey, dog, and rat.
    Swinney DC
    Drug Metab Dispos; 1990; 18(6):859-65. PubMed ID: 1981529
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Simultaneous transfection of COS-1 cells with mitochondrial and microsomal steroid hydroxylases: incorporation of a steroidogenic pathway into nonsteroidogenic cells.
    Zuber MX; Mason JI; Simpson ER; Waterman MR
    Proc Natl Acad Sci U S A; 1988 Feb; 85(3):699-703. PubMed ID: 2829199
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulation of cholesterol side-chain cleavage and 17 alpha-hydroxylase/lyase activities in proliferating human theca interna cells in long term monolayer culture.
    McAllister JM; Kerin JF; Trant JM; Estabrook RW; Mason JI; Waterman MR; Simpson ER
    Endocrinology; 1989 Oct; 125(4):1959-66. PubMed ID: 2676474
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The lithocholic acid 6 beta-hydroxylase cytochrome P-450, CYP 3A10, is an active catalyst of steroid-hormone 6 beta-hydroxylation.
    Chang TK; Teixeira J; Gil G; Waxman DJ
    Biochem J; 1993 Apr; 291 ( Pt 2)(Pt 2):429-33. PubMed ID: 8484723
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ovine steroid 17alpha-hydroxylase cytochrome P450: characteristics of the hydroxylase and lyase activities of the adrenal cortex enzyme.
    Swart P; Lombard N; Swart AC; van der Merwe T; Murry BA; Nicol M; Ian Mason J
    Arch Biochem Biophys; 2003 Jan; 409(1):145-52. PubMed ID: 12464253
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A single amino acid residue, Ala 105, confers 16alpha-hydroxylase activity to human cytochrome P450 17alpha-hydroxylase/17,20 lyase.
    Swart AC; Storbeck KH; Swart P
    J Steroid Biochem Mol Biol; 2010 Apr; 119(3-5):112-20. PubMed ID: 20043997
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Kinetic control of steroidogenesis by steroid concentration in guinea pig adrenal microsomes.
    Higuchi A; Kominami S; Takemori S
    Biochim Biophys Acta; 1991 Jul; 1084(3):240-6. PubMed ID: 1888770
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of electron transport in the regulation of the lyase activity of C21 side-chain cleavage P-450 from porcine adrenal and testicular microsomes.
    Yanagibashi K; Hall PF
    J Biol Chem; 1986 Jun; 261(18):8429-33. PubMed ID: 3487544
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In vitro effect of 16alpha-hydroxyprogesterone on the enzyme activities related to androgen production in human testes.
    Inano H; Tamaoki B
    Acta Endocrinol (Copenh); 1978 Aug; 88(4):768-77. PubMed ID: 581117
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Modulation of 17alpha-hydroxylase/17,20-lyase activity of guinea pig cytochrome P450c17 by site-directed mutagenesis.
    Beaudoin C; Lavallée B; Tremblay Y; Hum DW; Breton R; de Launoit Y; Bélanger A
    DNA Cell Biol; 1998 Aug; 17(8):707-15. PubMed ID: 9726253
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CYP17A1 exhibits 17αhydroxylase/17,20-lyase activity towards 11β-hydroxyprogesterone and 11-ketoprogesterone metabolites in the C11-oxy backdoor pathway.
    van Rooyen D; Yadav R; Scott EE; Swart AC
    J Steroid Biochem Mol Biol; 2020 May; 199():105614. PubMed ID: 32007561
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The function of recombinant cytochrome P450s in intact Escherichia coli cells: the 17 alpha-hydroxylation of progesterone and pregnenolone by P450c17.
    Shet MS; Fisher CW; Estabrook RW
    Arch Biochem Biophys; 1997 Mar; 339(1):218-25. PubMed ID: 9056252
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 39.