BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

407 related articles for article (PubMed ID: 8330339)

  • 1. Roles of different forms of cytochrome P450 in the activation of the promutagen 6-aminochrysene to genotoxic metabolites in human liver microsomes.
    Yamazaki H; Mimura M; Oda Y; Inui Y; Shiraga T; Iwasaki K; Guengerich FP; Shimada T
    Carcinogenesis; 1993 Jul; 14(7):1271-8. PubMed ID: 8330339
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of 6-aminochrysene to genotoxic products by different forms of rat liver cytochrome P450 in an O-acetyltransferase-overexpressing Salmonella typhimurium strain (NM2009).
    Yamazaki H; Shimada T
    Biochem Pharmacol; 1992 Sep; 44(5):913-20. PubMed ID: 1530660
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of trans-1,2-dihydro-1,2-dihydroxy-6-aminochrysene to genotoxic metabolites by rat and human cytochromes P450.
    Yamazaki H; Mimura M; Oda Y; Gonzalez FJ; el-Bayoumy K; Chae YH; Guengerich FP; Shimada T
    Carcinogenesis; 1994 Mar; 15(3):465-70. PubMed ID: 8118930
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Use of a newly developed tester strain Salmonella typhimurium NM2009 for the study of metabolic activation of carcinogenic aromatic amines by rat liver microsomal cytochrome P-450 enzymes.
    Yamazaki H; Oda Y; Shimada T
    Mutat Res; 1992 Oct; 272(2):183-92. PubMed ID: 1383750
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Participation of rat liver cytochrome P450 2E1 in the activation of N-nitrosodimethylamine and N-nitrosodiethylamine to products genotoxic in an acetyltransferase-overexpressing Salmonella typhimurium strain (NM2009).
    Yamazaki H; Oda Y; Funae Y; Imaoka S; Inui Y; Guengerich FP; Shimada T
    Carcinogenesis; 1992 Jun; 13(6):979-85. PubMed ID: 1600620
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes.
    Yamazaki H; Guo Z; Persmark M; Mimura M; Inoue K; Guengerich FP; Shimada T
    Mol Pharmacol; 1994 Sep; 46(3):568-77. PubMed ID: 7935340
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Genotoxic activation of 2-phenylbenzotriazole-type compounds by human cytochrome P4501A1 and N-acetyltransferase expressed in Salmonella typhimurium umu strains.
    Oda Y; Watanabe T; Terao Y; Nukaya H; Wakabayashi K
    Mutat Res; 2008 Jun; 654(1):52-7. PubMed ID: 18562244
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Roles of different cytochrome P450 enzymes in bioactivation of the potent hepatocarcinogen 3-methoxy-4-aminoazobenzene by rat and human liver microsomes.
    Yamazaki H; Degawa M; Funae Y; Imaoka S; Inui Y; Guengerich FP; Shimada T
    Carcinogenesis; 1991 Jan; 12(1):133-9. PubMed ID: 1988174
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of microsomal cytochrome P450 enzymes involved in the oxidation of xenobiotic chemicals in human fetal liver and adult lungs.
    Shimada T; Yamazaki H; Mimura M; Wakamiya N; Ueng YF; Guengerich FP; Inui Y
    Drug Metab Dispos; 1996 May; 24(5):515-22. PubMed ID: 8723730
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation of amino-alpha-carboline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and a copper phthalocyanine cellulose extract of cigarette smoke condensate by cytochrome P-450 enzymes in rat and human liver microsomes.
    Shimada T; Guengerich FP
    Cancer Res; 1991 Oct; 51(19):5284-91. PubMed ID: 1913651
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1.
    Shimada T; Hayes CL; Yamazaki H; Amin S; Hecht SS; Guengerich FP; Sutter TR
    Cancer Res; 1996 Jul; 56(13):2979-84. PubMed ID: 8674051
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Development of high sensitive umu test system: rapid detection of genotoxicity of promutagenic aromatic amines by Salmonella typhimurium strain NM2009 possessing high O-acetyltransferase activity.
    Oda Y; Yamazaki H; Watanabe M; Nohmi T; Shimada T
    Mutat Res; 1995 Apr; 334(2):145-56. PubMed ID: 7885366
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metabolic activation of carcinogenic 1-nitropyrene by human cytochrome P450 1B1 in Salmonella typhimurium strain expressing an O-acetyltransferase in SOS/umu assay.
    Hatanaka N; Yamazaki H; Oda Y; Guengerich FP; Nakajima M; Yokoi T
    Mutat Res; 2001 Oct; 497(1-2):223-33. PubMed ID: 11525925
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Catalysis of the oxidation of steroid and stilbene estrogens to estrogen quinone metabolites by the beta-naphthoflavone-inducible cytochrome P450 IA family.
    Roy D; Bernhardt A; Strobel HW; Liehr JG
    Arch Biochem Biophys; 1992 Aug; 296(2):450-6. PubMed ID: 1632637
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metabolic deactivation of furylfuramide by cytochrome P450 in human and rat liver microsomes.
    Shimada T; Yamazaki H; Shimura H; Tanaka R; Guengerich FP
    Carcinogenesis; 1990 Jan; 11(1):103-10. PubMed ID: 2403855
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differential roles of cytochromes P450 2D1, 2C11, and 1A1/2 in the hydroxylation of bufuralol by rat liver microsomes.
    Mimura M; Yamazaki H; Sugahara C; Hiroi T; Funae Y; Shimada T
    Biochem Pharmacol; 1994 Jun; 47(11):1957-63. PubMed ID: 7912070
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Induction of liver microsomal cytochrome P450 in cynomolgus monkeys.
    Bullock P; Pearce R; Draper A; Podval J; Bracken W; Veltman J; Thomas P; Parkinson A
    Drug Metab Dispos; 1995 Jul; 23(7):736-48. PubMed ID: 7587963
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation and inactivation of carcinogenic dihaloalkanes and other compounds by glutathione S-transferase 5-5 in Salmonella typhimurium tester strain NM5004.
    Shimada T; Yamazaki H; Oda Y; Hiratsuka A; Watabe T; Guengerich FP
    Chem Res Toxicol; 1996; 9(1):333-40. PubMed ID: 8924613
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes.
    Yamazaki H; Inui Y; Yun CH; Guengerich FP; Shimada T
    Carcinogenesis; 1992 Oct; 13(10):1789-94. PubMed ID: 1423839
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of cytochrome P-450 2B6 in human liver microsomes.
    Mimura M; Baba T; Yamazaki H; Ohmori S; Inui Y; Gonzalez FJ; Guengerich FP; Shimada T
    Drug Metab Dispos; 1993; 21(6):1048-56. PubMed ID: 7905383
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.