BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

98 related articles for article (PubMed ID: 8339275)

  • 1. Decreased folylpolyglutamate synthetase expression: a novel mechanism of fluorouracil resistance.
    Wang FS; Aschele C; Sobrero A; Chang YM; Bertino JR
    Cancer Res; 1993 Aug; 53(16):3677-80. PubMed ID: 8339275
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel mechanism(s) of resistance to 5-fluorouracil in human colon cancer (HCT-8) sublines following exposure to two different clinically relevant dose schedules.
    Aschele C; Sobrero A; Faderan MA; Bertino JR
    Cancer Res; 1992 Apr; 52(7):1855-64. PubMed ID: 1532346
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Determinants of cytotoxicity with prolonged exposure to fluorouracil in human colon cancer cells.
    Ren Q; Van Groeningen CJ; Hardcastle A; Aherne GW; Geoffroy F; Allegra CJ; Johnston PG; Grem JL
    Oncol Res; 1997; 9(2):77-88. PubMed ID: 9167189
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In vitro synergism between 5-fluorouracil and natural beta interferon in human colon carcinoma cells.
    Guglielmi A; Aschele C; Mori A; Baldo C; Russo P; Debernardis D; Valenti M; Bruno S; Taverna M; Rosso R
    Clin Cancer Res; 1995 Nov; 1(11):1337-44. PubMed ID: 9815929
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Enhanced cytotoxicity with interleukin-1 alpha and 5-fluorouracil in HCT116 colon cancer cells.
    Geoffroy FJ; Allegra CJ; Sinha B; Grem JL
    Oncol Res; 1994; 6(12):581-91. PubMed ID: 7787251
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pretreatment of colon carcinoma cells with Tomudex enhances 5-fluorouracil cytotoxicity.
    Longo GS; Izzo J; Chang YM; Tong WP; Zielinski Z; Gorlick R; Chou TC; Bertino JR
    Clin Cancer Res; 1998 Feb; 4(2):469-73. PubMed ID: 9516938
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Folylpolyglutamate synthetase expression in antifolate-sensitive and -resistant human cell lines.
    McGuire JJ; Russell CA
    Oncol Res; 1998; 10(4):193-200. PubMed ID: 9778690
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In vivo kinetics of thymidylate synthetase inhibition of 5-fluorouracil-sensitive and -resistant murine colon adenocarcinomas.
    Spears CP; Shahinian AH; Moran RG; Heidelberger C; Corbett TH
    Cancer Res; 1982 Feb; 42(2):450-6. PubMed ID: 6173112
    [TBL] [Abstract][Full Text] [Related]  

  • 9. NAD(P)H:quinone oxidoreductase expression and mitomycin C resistance developed by human colon cancer HCT 116 cells.
    Pan SS; Forrest GL; Akman SA; Hu LT
    Cancer Res; 1995 Jan; 55(2):330-5. PubMed ID: 7812966
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines.
    van Triest B; Pinedo HM; van Hensbergen Y; Smid K; Telleman F; Schoenmakers PS; van der Wilt CL; van Laar JA; Noordhuis P; Jansen G; Peters GJ
    Clin Cancer Res; 1999 Mar; 5(3):643-54. PubMed ID: 10100718
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 5-Fluorouracil incorporation into DNA of CF-1 mouse bone marrow cells as a possible mechanism of toxicity.
    Schuetz JD; Wallace HJ; Diasio RB
    Cancer Res; 1984 Apr; 44(4):1358-63. PubMed ID: 6704957
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Therapeutic efficacy of fluoropyrimidines depends on the duration of thymidylate synthase inhibition in the murine colon 26-B carcinoma tumor model.
    van Laar JA; van der Wilt CL; Rustum YM; Noordhuis P; Smid K; Pinedo HM; Peters GJ
    Clin Cancer Res; 1996 Aug; 2(8):1327-33. PubMed ID: 9816304
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Modulation of 5-fluorouracil metabolism and cytotoxicity by antimetabolite pretreatment in human colorectal adenocarcinoma HCT-8.
    Benz C; Cadman E
    Cancer Res; 1981 Mar; 41(3):994-9. PubMed ID: 7459888
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of L-histidinol on the metabolism of 5-fluorouracil in the BALB/c x DBA/8 F1 murine tumor system.
    Sawyer RC; Stolfi RL; Martin DS
    Cancer Res; 1988 Dec; 48(23):6664-8. PubMed ID: 2460227
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Defective facilitated diffusion of nucleosides, a primary mechanism of resistance to 5-fluoro-2'-deoxyuridine in the HCT-8 human carcinoma line.
    Sobrero AF; Moir RD; Bertino JR; Handschumacher RE
    Cancer Res; 1985 Jul; 45(7):3155-60. PubMed ID: 3159474
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synergism and lack of cross-resistance between short-term and continuous exposure to fluorouracil in human colon adenocarcinoma cells.
    Sobrero AF; Aschele C; Guglielmi AP; Mori AM; Melioli GG; Rosso R; Bertino JR
    J Natl Cancer Inst; 1993 Dec; 85(23):1937-44. PubMed ID: 8230285
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Increased levels of thymidylate synthetase in cells exposed to 5-fluorouracil.
    Washtien WL
    Mol Pharmacol; 1984 Jan; 25(1):171-7. PubMed ID: 6708932
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Detection and quantitation of thymidylate synthase mRNA in human colon adenocarcinoma cell line resistant to 5-fluorouracil by competitive PCR.
    Shibata J; Aiba K; Shibata H; Minowa S; Horikoshi N
    Anticancer Res; 1998; 18(3A):1457-63. PubMed ID: 9673356
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of 5,8-dideazaisopteroylglutamate and its possible tri-gamma-glutamyl metabolite (5,8-dideazaisoPteGlu3) on colon adenocarcinoma, and the folate dependent enzymes thymidylate synthase and dihydrofolate reductase.
    Fernandes DJ; Cardenas RM; Bertino JR; Hynes JB
    Adv Exp Med Biol; 1983; 163():341-57. PubMed ID: 6688493
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Decreased folylpolyglutamate synthetase activity in tumors resistant to fluorouracil-folinic acid treatment: clinical data.
    Chazal M; Cheradame S; Formento JL; Francoual M; Formento P; Etienne MC; François E; Richelme H; Mousseau M; Letoublon C; Pezet D; Cure H; Seitz JF; Milano G
    Clin Cancer Res; 1997 Apr; 3(4):553-7. PubMed ID: 9815719
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.