177 related articles for article (PubMed ID: 8340361)
21. Hypersensitive mousetraps, alpha1-antitrypsin deficiency and dementia.
Lomas DA; Lourbakos A; Cumming SA; Belorgey D
Biochem Soc Trans; 2002 Apr; 30(2):89-92. PubMed ID: 12023831
[TBL] [Abstract][Full Text] [Related]
22. The Z type variation of human alpha 1-antitrypsin causes a protein folding defect.
Yu MH; Lee KN; Kim J
Nat Struct Biol; 1995 May; 2(5):363-7. PubMed ID: 7664092
[TBL] [Abstract][Full Text] [Related]
23. Loop-sheet polymerization: the mechanism of alpha1-antitrypsin deficiency.
Lomas DA
Respir Med; 2000 Aug; 94 Suppl C():S3-6. PubMed ID: 10954247
[TBL] [Abstract][Full Text] [Related]
24. Structural change in β-sheet A of Z α(1)-antitrypsin is responsible for accelerated polymerization and disease.
Knaupp AS; Bottomley SP
J Mol Biol; 2011 Nov; 413(4):888-98. PubMed ID: 21945526
[TBL] [Abstract][Full Text] [Related]
25. A thermostable mutation located at the hydrophobic core of alpha 1-antitrypsin suppresses the folding defect of the Z-type variant.
Kim J; Lee KN; Yi GS; Yu MH
J Biol Chem; 1995 Apr; 270(15):8597-601. PubMed ID: 7721761
[TBL] [Abstract][Full Text] [Related]
26. Deficiency Mutations of Alpha-1 Antitrypsin. Effects on Folding, Function, and Polymerization.
Haq I; Irving JA; Saleh AD; Dron L; Regan-Mochrie GL; Motamedi-Shad N; Hurst JR; Gooptu B; Lomas DA
Am J Respir Cell Mol Biol; 2016 Jan; 54(1):71-80. PubMed ID: 26091018
[TBL] [Abstract][Full Text] [Related]
27. The mechanism of alpha 1-antitrypsin polymerization probed by fluorescence spectroscopy.
James EL; Bottomley SP
Arch Biochem Biophys; 1998 Aug; 356(2):296-300. PubMed ID: 9705220
[TBL] [Abstract][Full Text] [Related]
28. A novel monoclonal antibody to characterize pathogenic polymers in liver disease associated with alpha1-antitrypsin deficiency.
Miranda E; Pérez J; Ekeowa UI; Hadzic N; Kalsheker N; Gooptu B; Portmann B; Belorgey D; Hill M; Chambers S; Teckman J; Alexander GJ; Marciniak SJ; Lomas DA
Hepatology; 2010 Sep; 52(3):1078-88. PubMed ID: 20583215
[TBL] [Abstract][Full Text] [Related]
29. Lung polymers in Z alpha1-antitrypsin deficiency-related emphysema.
Elliott PR; Bilton D; Lomas DA
Am J Respir Cell Mol Biol; 1998 May; 18(5):670-4. PubMed ID: 9569237
[TBL] [Abstract][Full Text] [Related]
30. Wild-type alpha 1-antitrypsin is in the canonical inhibitory conformation.
Elliott PR; Abrahams JP; Lomas DA
J Mol Biol; 1998 Jan; 275(3):419-25. PubMed ID: 9466920
[TBL] [Abstract][Full Text] [Related]
31. Molecular Mechanism of Z α1-Antitrypsin Deficiency.
Huang X; Zheng Y; Zhang F; Wei Z; Wang Y; Carrell RW; Read RJ; Chen GQ; Zhou A
J Biol Chem; 2016 Jul; 291(30):15674-86. PubMed ID: 27246852
[TBL] [Abstract][Full Text] [Related]
32. [Alpha 1-antitrypsin genes in patients with alpha 1AT deficiency in Japan: mutational analysis and allelic background].
Nukiwa T; Seyama K; Takahashi H; Kira S
Nihon Kyobu Shikkan Gakkai Zasshi; 1992 Aug; 30(8):1420-6. PubMed ID: 1434214
[TBL] [Abstract][Full Text] [Related]
33. Alpha 1-antitrypsin polymerisation can occur by both loop A and C sheet mechanisms.
Bottomley SP; Hopkins PC; Whisstock JC
Biochem Biophys Res Commun; 1998 Oct; 251(1):1-5. PubMed ID: 9790897
[TBL] [Abstract][Full Text] [Related]
34. A naturally occurring nonpolymerogenic mutant of alpha 1-antitrypsin characterized by prolonged retention in the endoplasmic reticulum.
Lin L; Schmidt B; Teckman J; Perlmutter DH
J Biol Chem; 2001 Sep; 276(36):33893-8. PubMed ID: 11427540
[TBL] [Abstract][Full Text] [Related]
35. [Alpha 1-antitrypsin deficiency (Siiyama) with pulmonary emphysema].
Kadono K; Sakamoto T; Ohtsuka M; Kanashiki M; Murakami O; Hagiya M; Ishii Y; Nomura A; Satoh H; Inoue M; Uchida Y; Homma T; Sekizawa K; Hasegawa S
Nihon Kokyuki Gakkai Zasshi; 1999 Sep; 37(9):733-8. PubMed ID: 10540843
[TBL] [Abstract][Full Text] [Related]
36. Reactive centre loop mutants of α-1-antitrypsin reveal position-specific effects on intermediate formation along the polymerization pathway.
Haq I; Irving JA; Faull SV; Dickens JA; Ordóñez A; Belorgey D; Gooptu B; Lomas DA
Biosci Rep; 2013 Jun; 33(3):. PubMed ID: 23659468
[TBL] [Abstract][Full Text] [Related]
37. A novel mode of polymerization of alpha1-proteinase inhibitor.
Marszal E; Danino D; Shrake A
J Biol Chem; 2003 May; 278(22):19611-8. PubMed ID: 12649292
[TBL] [Abstract][Full Text] [Related]
38. Alpha(1)-antitrypsin deficiency, liver disease and emphysema.
Parfrey H; Mahadeva R; Lomas DA
Int J Biochem Cell Biol; 2003 Jul; 35(7):1009-14. PubMed ID: 12672469
[TBL] [Abstract][Full Text] [Related]
39. Polymers of Z alpha1-antitrypsin co-localize with neutrophils in emphysematous alveoli and are chemotactic in vivo.
Mahadeva R; Atkinson C; Li Z; Stewart S; Janciauskiene S; Kelley DG; Parmar J; Pitman R; Shapiro SD; Lomas DA
Am J Pathol; 2005 Feb; 166(2):377-86. PubMed ID: 15681822
[TBL] [Abstract][Full Text] [Related]
40. Dynamic local unfolding in the serpin α-1 antitrypsin provides a mechanism for loop insertion and polymerization.
Krishnan B; Gierasch LM
Nat Struct Mol Biol; 2011 Feb; 18(2):222-6. PubMed ID: 21258324
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
