223 related articles for article (PubMed ID: 8347150)
21. Chemotherapy-induced O(6)-benzylguanine-resistant alkyltransferase mutations in mismatch-deficient colon cancer.
Liu L; Schwartz S; Davis BM; Gerson SL
Cancer Res; 2002 Jun; 62(11):3070-6. PubMed ID: 12036916
[TBL] [Abstract][Full Text] [Related]
22. O6-benzylguanine-mediated enhancement of nitrosourea activity in Mer- central nervous system tumor xenografts--implications for clinical trials.
Keir ST; Dolan ME; Pegg AE; Lawless A; Moschel RC; Bigner DD; Friedman HS
Cancer Chemother Pharmacol; 2000; 45(6):437-40. PubMed ID: 10854129
[TBL] [Abstract][Full Text] [Related]
23. O6-benzylguanine potentiates the antitumor effect of locally delivered carmustine against an intracranial rat glioma.
Rhines LD; Sampath P; Dolan ME; Tyler BM; Brem H; Weingart J
Cancer Res; 2000 Nov; 60(22):6307-10. PubMed ID: 11103789
[TBL] [Abstract][Full Text] [Related]
24. Protection of CHO cells by mutant forms of O6-alkylguanine-DNA alkyltransferase from killing by 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU) plus O6-benzylguanine or O6-benzyl-8-oxoguanine.
Loktionova NA; Xu-Welliver M; Crone TM; Kanugula S; Pegg AE
Biochem Pharmacol; 1999 Jul; 58(2):237-44. PubMed ID: 10423163
[TBL] [Abstract][Full Text] [Related]
25. Effect of O6-benzylguanine analogues on sensitivity of human tumor cells to the cytotoxic effects of alkylating agents.
Dolan ME; Mitchell RB; Mummert C; Moschel RC; Pegg AE
Cancer Res; 1991 Jul; 51(13):3367-72. PubMed ID: 1647266
[TBL] [Abstract][Full Text] [Related]
26. Brain tumor cell lines resistant to O6-benzylguanine/1,3-bis(2-chloroethyl)-1-nitrosourea chemotherapy have O6-alkylguanine-DNA alkyltransferase mutations.
Bacolod MD; Johnson SP; Pegg AE; Dolan ME; Moschel RC; Bullock NS; Fang Q; Colvin OM; Modrich P; Bigner DD; Friedman HS
Mol Cancer Ther; 2004 Sep; 3(9):1127-35. PubMed ID: 15367707
[TBL] [Abstract][Full Text] [Related]
27. O6-alkylguanine DNA-alkyltransferase is not a major determinant of sensitivity to 1,3-bis(2-chloroethyl)-1-nitrosourea in four medulloblastoma cell lines.
Silber JR; Bobola MS; Ewers TG; Muramoto M; Berger MS
Oncol Res; 1992; 4(6):241-8. PubMed ID: 1421617
[TBL] [Abstract][Full Text] [Related]
28. Modulation of mammalian O6-alkylguanine-DNA alkyltransferase in vivo by O6-benzylguanine and its effect on the sensitivity of a human glioma tumor to 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea.
Dolan ME; Stine L; Mitchell RB; Moschel RC; Pegg AE
Cancer Commun; 1990; 2(11):371-7. PubMed ID: 2242301
[TBL] [Abstract][Full Text] [Related]
29. Anti-neoplastic activity of sequenced administration of O6-benzylguanine, streptozotocin, and 1,3-bis(2-chloroethyl)-1-nitrosourea in vitro and in vivo.
Marathi UK; Dolan ME; Erickson LC
Biochem Pharmacol; 1994 Nov; 48(11):2127-34. PubMed ID: 7802703
[TBL] [Abstract][Full Text] [Related]
30. Selection for G156A O6-methylguanine DNA methyltransferase gene-transduced hematopoietic progenitors and protection from lethality in mice treated with O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea.
Davis BM; Reese JS; Koç ON; Lee K; Schupp JE; Gerson SL
Cancer Res; 1997 Nov; 57(22):5093-9. PubMed ID: 9371508
[TBL] [Abstract][Full Text] [Related]
31. 3-aminobenzamide and/or O6-benzylguanine evaluated as an adjuvant to temozolomide or BCNU treatment in cell lines of variable mismatch repair status and O6-alkylguanine-DNA alkyltransferase activity.
Wedge SR; Porteous JK; Newlands ES
Br J Cancer; 1996 Oct; 74(7):1030-6. PubMed ID: 8855970
[TBL] [Abstract][Full Text] [Related]
32. Prolonged depletion of O6-methylguanine DNA methyltransferase activity following exposure to O6-benzylguanine with or without streptozotocin enhances 1,3-bis(2-chloroethyl)-1-nitrosourea sensitivity in vitro.
Marathi UK; Kroes RA; Dolan ME; Erickson LC
Cancer Res; 1993 Sep; 53(18):4281-6. PubMed ID: 8364924
[TBL] [Abstract][Full Text] [Related]
33. Intraarterial O6-benzylguanine enables the specific therapy of nitrosourea-resistant intracranial human glioma xenografts in athymic rats with 1,3-bis(2-chloroethyl)-1-nitrosourea.
Kurpad SN; Dolan ME; McLendon RE; Archer GE; Moschel RC; Pegg AE; Bigner DD; Friedman HS
Cancer Chemother Pharmacol; 1997; 39(4):307-16. PubMed ID: 9025771
[TBL] [Abstract][Full Text] [Related]
34. Potentiation of BCNU antitumor efficacy by 9-substituted O6-benzylguanines. Effect of metabolism.
Kokkinakis DM; Moschel RC; Pegg AE; Schold SC
Cancer Chemother Pharmacol; 2000; 45(1):69-77. PubMed ID: 10647505
[TBL] [Abstract][Full Text] [Related]
35. Modulation of nitrosourea resistance in human colon cancer by O6-methylguanine.
Gerson SL; Berger NA; Arce C; Petzold SJ; Willson JK
Biochem Pharmacol; 1992 Mar; 43(5):1101-7. PubMed ID: 1554383
[TBL] [Abstract][Full Text] [Related]
36. Effect of O6-benzylguanine on alkylating agent-induced toxicity and mutagenicity. In Chinese hamster ovary cells expressing wild-type and mutant O6-alkylguanine-DNA alkyltransferases.
Cai Y; Wu MH; Xu-Welliver M; Pegg AE; Ludeman SM; Dolan ME
Cancer Res; 2000 Oct; 60(19):5464-9. PubMed ID: 11034089
[TBL] [Abstract][Full Text] [Related]
37. Human CD34+ hematopoietic progenitors have low, cytokine-unresponsive O6-alkylguanine-DNA alkyltransferase and are sensitive to O6-benzylguanine plus BCNU.
Gerson SL; Phillips W; Kastan M; Dumenco LL; Donovan C
Blood; 1996 Sep; 88(5):1649-55. PubMed ID: 8781420
[TBL] [Abstract][Full Text] [Related]
38. Tumour levels of O6-alkylguanine-DNA-alkyltransferase and sensitivity to BCNU of human xenografts.
Tagliabue G; Citti L; Massazza G; Damia G; Giavazzi R; D'Incalci M
Anticancer Res; 1992; 12(6B):2123-5. PubMed ID: 1295458
[TBL] [Abstract][Full Text] [Related]
39. Influence of O6-benzylguanine on the anti-tumour activity and normal tissue toxicity of 1,3-bis(2-chloroethyl)-1-nitrosourea and molecular combinations of 5-fluorouracil and 2-chloroethyl-1-nitrosourea in mice.
Bibby MC; Thompson MJ; Rafferty JA; Margison GP; McElhinney RS
Br J Cancer; 1999 Mar; 79(9-10):1332-9. PubMed ID: 10188873
[TBL] [Abstract][Full Text] [Related]
40. Treatment of human brain tumor xenografts with O6-benzyl-2'-deoxyguanosine and BCNU.
Schold SC; Kokkinakis DM; Rudy JL; Moschel RC; Pegg AE
Cancer Res; 1996 May; 56(9):2076-81. PubMed ID: 8616853
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
