These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
106 related articles for article (PubMed ID: 8352551)
1. Development, characterization and application of an antibody against 5-fluoro-2'deoxyuridine-5'monophosphate, the active metabolite of 5-fluorouracil. Peters GJ; Laurensse E; Steinbusch HW; De Vente J; Smid K; Van der Wilt CL; Pinedo HM Anticancer Res; 1993; 13(4):835-9. PubMed ID: 8352551 [TBL] [Abstract][Full Text] [Related]
2. Relationship of dUMP and free FdUMP pools to inhibition of thymidylate synthase by 5-fluorouracil. Berger SH; Hakala MT Mol Pharmacol; 1984 Mar; 25(2):303-9. PubMed ID: 6608049 [TBL] [Abstract][Full Text] [Related]
3. Mechanisms of innate resistance to thymidylate synthase inhibition after 5-fluorouracil. Spears CP; Gustavsson BG; Berne M; Frösing R; Bernstein L; Hayes AA Cancer Res; 1988 Oct; 48(20):5894-900. PubMed ID: 3167844 [TBL] [Abstract][Full Text] [Related]
4. Biochemical determinants of 5-fluorouracil response in vivo. The role of deoxyuridylate pool expansion. Myers CE; Young RC; Chabner BA J Clin Invest; 1975 Nov; 56(5):1231-8. PubMed ID: 1184747 [TBL] [Abstract][Full Text] [Related]
5. Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines. van Triest B; Pinedo HM; van Hensbergen Y; Smid K; Telleman F; Schoenmakers PS; van der Wilt CL; van Laar JA; Noordhuis P; Jansen G; Peters GJ Clin Cancer Res; 1999 Mar; 5(3):643-54. PubMed ID: 10100718 [TBL] [Abstract][Full Text] [Related]
7. Determinants of cytotoxicity with prolonged exposure to fluorouracil in human colon cancer cells. Ren Q; Van Groeningen CJ; Hardcastle A; Aherne GW; Geoffroy F; Allegra CJ; Johnston PG; Grem JL Oncol Res; 1997; 9(2):77-88. PubMed ID: 9167189 [TBL] [Abstract][Full Text] [Related]
8. Biphasic binding of 5-fluoro-2'-deoxyuridylate to human thymidylate synthase. Reilly RT; Barbour KW; Dunlap RB; Berger FG Mol Pharmacol; 1995 Jul; 48(1):72-9. PubMed ID: 7623777 [TBL] [Abstract][Full Text] [Related]
9. Ternary complex formation with 5-fluoro-2'-deoxyuridylate and the kinetic properties of thymidylate synthase from Lactobacillus leichmannii. Rao KN Indian J Biochem Biophys; 1993 Apr; 30(2):103-10. PubMed ID: 8354517 [TBL] [Abstract][Full Text] [Related]
10. The number of 5-fluoro-2'-deoxyuridine-5'-monophosphate binding sites and reduced folate pool in human colorectal carcinoma tissues: changes after tegafur and uracil treatment. Omura K; Kawakami K; Kanehira E; Nagasato A; Kawashima S; Tawaraya K; Watanabe S; Hirano K; Shirasaka T; Watanabe Y Cancer Res; 1995 Sep; 55(17):3897-901. PubMed ID: 7641209 [TBL] [Abstract][Full Text] [Related]
11. Production and characterization of monoclonal antibodies that localize human thymidylate synthase in the cytoplasm of human cells and tissue. Johnston PG; Liang CM; Henry S; Chabner BA; Allegra CJ Cancer Res; 1991 Dec; 51(24):6668-76. PubMed ID: 1720706 [TBL] [Abstract][Full Text] [Related]
12. Molecular mechanism of thymidylate synthase-catalyzed reaction and interaction of the enzyme with 2- and/or 4-substituted analogues of dUMP and 5-fluoro-dUMP. Rode W; Leś A Acta Biochim Pol; 1996; 43(1):133-42. PubMed ID: 8790719 [TBL] [Abstract][Full Text] [Related]
13. Thymidylate synthetase inhibition in malignant tumors and normal liver of patients given intravenous 5-fluorouracil. Spears CP; Gustavsson BG; Mitchell MS; Spicer D; Berne M; Bernstein L; Danenberg PV Cancer Res; 1984 Sep; 44(9):4144-50. PubMed ID: 6744325 [TBL] [Abstract][Full Text] [Related]
14. Biochemical determinants of responsiveness to 5-fluorouracil and its derivatives in xenografts of human colorectal adenocarcinomas in mice. Houghton JA; Maroda SJ; Phillips JO; Houghton PJ Cancer Res; 1981 Jan; 41(1):144-9. PubMed ID: 7448754 [TBL] [Abstract][Full Text] [Related]
15. Simultaneous quantification of 5-FU, 5-FUrd, 5-FdUrd, 5-FdUMP, dUMP and TMP in cultured cell models by LC-MS/MS. Carli D; Honorat M; Cohen S; Megherbi M; Vignal B; Dumontet C; Payen L; Guitton J J Chromatogr B Analyt Technol Biomed Life Sci; 2009 Oct; 877(27):2937-44. PubMed ID: 19620028 [TBL] [Abstract][Full Text] [Related]
16. Kinetic studies on drug-resistant variants of Escherichia coli thymidylate synthase: functional effects of amino acid substitutions at residue 4. Mahdavian E; Spencer HT; Dunlap RB Arch Biochem Biophys; 1999 Aug; 368(2):257-64. PubMed ID: 10441376 [TBL] [Abstract][Full Text] [Related]
17. Properties of a defined mutant of Escherichia coli thymidylate synthase. Maley GF; Maley F J Biol Chem; 1988 Jun; 263(16):7620-7. PubMed ID: 3286637 [TBL] [Abstract][Full Text] [Related]
18. Acyclic analogues of 5-fluoro-dUMP and 5-fluoro-2'-deoxyuridine: synthesis and inhibition of thymidylate synthase and tumour cell growth. Felczak K; Gołos B; Dzik JM; Rode W; Bretner M; Shugar D; Kulikowski T Acta Biochim Pol; 1998; 45(1):75-82. PubMed ID: 9701498 [TBL] [Abstract][Full Text] [Related]
19. Assay of intracellular free and macromolecular-bound metabolites of 5-fluorodeoxyuridine and 5-fluorouracil. Washtien WL; Santi DV Cancer Res; 1979 Sep; 39(9):3397-404. PubMed ID: 157805 [TBL] [Abstract][Full Text] [Related]
20. A molecular modeling study of the interaction of 2'-fluoro-substituted analogues of dUMP/FdUMP with thymidylate synthase. Jarmuła A; Dowierciał A; Rode W Bioorg Med Chem Lett; 2008 Apr; 18(8):2701-8. PubMed ID: 18362071 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]