BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

230 related articles for article (PubMed ID: 8357792)

  • 1. Three-dimensional structures and properties of a transforming and a nontransforming glycine-12 mutant of p21H-ras.
    Franken SM; Scheidig AJ; Krengel U; Rensland H; Lautwein A; Geyer M; Scheffzek K; Goody RS; Kalbitzer HR; Pai EF
    Biochemistry; 1993 Aug; 32(33):8411-20. PubMed ID: 8357792
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Kinetic and structural analysis of the Mg(2+)-binding site of the guanine nucleotide-binding protein p21H-ras.
    John J; Rensland H; Schlichting I; Vetter I; Borasio GD; Goody RS; Wittinghofer A
    J Biol Chem; 1993 Jan; 268(2):923-9. PubMed ID: 8419371
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of glutamine-61 in the hydrolysis of GTP by p21H-ras: an experimental and theoretical study.
    Frech M; Darden TA; Pedersen LG; Foley CK; Charifson PS; Anderson MW; Wittinghofer A
    Biochemistry; 1994 Mar; 33(11):3237-44. PubMed ID: 8136358
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Three-dimensional structure of p21 in the active conformation and analysis of an oncogenic mutant.
    Wittinghofer F; Krengel U; John J; Kabsch W; Pai EF
    Environ Health Perspect; 1991 Jun; 93():11-5. PubMed ID: 1773783
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Linear free energy relationships in the intrinsic and GTPase activating protein-stimulated guanosine 5'-triphosphate hydrolysis of p21ras.
    Schweins T; Geyer M; Kalbitzer HR; Wittinghofer A; Warshel A
    Biochemistry; 1996 Nov; 35(45):14225-31. PubMed ID: 8916907
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An NMR comparison of the changes produced by different guanosine 5'-triphosphate analogs in wild-type and oncogenic mutant p21ras.
    Miller AF; Halkides CJ; Redfield AG
    Biochemistry; 1993 Jul; 32(29):7367-76. PubMed ID: 8338834
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Site-directed mutagenesis, fluorescence, and two-dimensional NMR studies on microenvironments of effector region aromatic residues of human c-Ha-Ras protein.
    Yamasaki K; Shirouzu M; Muto Y; Fujita-Yoshigaki J; Koide H; Ito Y; Kawai G; Hattori S; Yokoyama S; Nishimura S
    Biochemistry; 1994 Jan; 33(1):65-73. PubMed ID: 8286364
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Three-dimensional structure and properties of wild-type and mutant H-ras-encoded p21.
    Wittinghofer A; Franken SM; Scheidig AJ; Rensland H; Lautwein A; Pai EF; Goody RS
    Ciba Found Symp; 1993; 176():6-21; discussion 21-7. PubMed ID: 8299426
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Three-dimensional structure of p21H-ras and its implications.
    Wittinghofer F
    Semin Cancer Biol; 1992 Aug; 3(4):189-98. PubMed ID: 1421163
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of the putative GTP-binding site residues of Escherichia coli adenylosuccinate synthetase by site-directed mutagenesis.
    Kang C; Fromm HJ
    Arch Biochem Biophys; 1994 May; 310(2):475-80. PubMed ID: 8179335
    [TBL] [Abstract][Full Text] [Related]  

  • 11. X-ray crystal structures of transforming p21 ras mutants suggest a transition-state stabilization mechanism for GTP hydrolysis.
    Privé GG; Milburn MV; Tong L; de Vos AM; Yamaizumi Z; Nishimura S; Kim SH
    Proc Natl Acad Sci U S A; 1992 Apr; 89(8):3649-53. PubMed ID: 1565661
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Guanine-nucleotide binding activity, interaction with GTPase-activating protein and solution conformation of the human c-Ha-Ras protein catalytic domain are retained upon deletion of C-terminal 18 amino acid residues.
    Fujita-Yoshigaki J; Ito Y; Yamasaki K; Muto Y; Miyazawa T; Nishimura S; Yokoyama S
    J Protein Chem; 1992 Dec; 11(6):731-9. PubMed ID: 1466766
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis.
    Schlichting I; Almo SC; Rapp G; Wilson K; Petratos K; Lentfer A; Wittinghofer A; Kabsch W; Pai EF; Petsko GA
    Nature; 1990 May; 345(6273):309-15. PubMed ID: 2111463
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ras-catalyzed hydrolysis of GTP: a new perspective from model studies.
    Maegley KA; Admiraal SJ; Herschlag D
    Proc Natl Acad Sci U S A; 1996 Aug; 93(16):8160-6. PubMed ID: 8710841
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Crystal structures at 2.2 A resolution of the catalytic domains of normal ras protein and an oncogenic mutant complexed with GDP.
    Tong LA; de Vos AM; Milburn MV; Kim SH
    J Mol Biol; 1991 Feb; 217(3):503-16. PubMed ID: 1899707
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanisms of guanosine triphosphate hydrolysis by Ras and Ras-GAP proteins as rationalized by ab initio QM/MM simulations.
    Grigorenko BL; Nemukhin AV; Shadrina MS; Topol IA; Burt SK
    Proteins; 2007 Feb; 66(2):456-66. PubMed ID: 17094109
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutants of Rab3A analogous to oncogenic Ras mutants. Sensitivity to Rab3A-GTPase activating protein and Rab3A-guanine nucleotide releasing factor.
    Brondyk WH; McKiernan CJ; Burstein ES; Macara IG
    J Biol Chem; 1993 May; 268(13):9410-5. PubMed ID: 8387493
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mapping the nucleotide-dependent conformational change of human N-ras p21 in solution by heteronuclear-edited proton-observed NMR methods.
    Hu JS; Redfield AG
    Biochemistry; 1993 Jul; 32(26):6763-72. PubMed ID: 8329399
    [TBL] [Abstract][Full Text] [Related]  

  • 19. GTP hydrolysis mechanisms in ras p21 and in the ras-GAP complex studied by fluorescence measurements on tryptophan mutants.
    Antonny B; Chardin P; Roux M; Chabre M
    Biochemistry; 1991 Aug; 30(34):8287-95. PubMed ID: 1883817
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular dynamics simulations of Gly-12-->Val mutant of p21(ras): dynamic inhibition mechanism.
    Futatsugi N; Tsuda M
    Biophys J; 2001 Dec; 81(6):3483-8. PubMed ID: 11721009
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.