134 related articles for article (PubMed ID: 8361949)
21. The identification of [2-(14)C]2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine metabolites in humans.
Malfatti MA; Kulp KS; Knize MG; Davis C; Massengill JP; Williams S; Nowell S; MacLeod S; Dingley KH; Turteltaub KW; Lang NP; Felton JS
Carcinogenesis; 1999 Apr; 20(4):705-13. PubMed ID: 10223203
[TBL] [Abstract][Full Text] [Related]
22. Metabolic activation of heterocyclic amine food mutagens in the mammary gland of lactating Fischer 344 rats.
Davis CD; Ghoshal A; Schut HA; Snyderwine EG
Cancer Lett; 1994 Aug; 84(1):67-73. PubMed ID: 7915639
[TBL] [Abstract][Full Text] [Related]
23. Antimutagenic effects and possible mechanisms of action of vitamins and related compounds against genotoxic heterocyclic amines from cooked food.
Edenharder R; Worf-Wandelburg A; Decker M; Platt KL
Mutat Res; 1999 Jul; 444(1):235-48. PubMed ID: 10477359
[TBL] [Abstract][Full Text] [Related]
24. Metabolic formation, synthesis and genotoxicity of the N-hydroxy derivative of the food mutagen 2-amino-1-methyl-6-phenylimidazo (4,5-b) pyridine (PhIP).
Frandsen H; Rasmussen ES; Nielsen PA; Farmer P; Dragsted L; Larsen JC
Mutagenesis; 1991 Jan; 6(1):93-8. PubMed ID: 1903830
[TBL] [Abstract][Full Text] [Related]
25. Cytochromes P450 in cynomolgus monkeys mutagenically activate 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) but not 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx).
Sadrieh N; Snyderwine EG
Carcinogenesis; 1995 Jul; 16(7):1549-55. PubMed ID: 7614688
[TBL] [Abstract][Full Text] [Related]
26. Inhibition of the metabolism of mutagens occurring in food by arachidonic acid.
Ho TA; Coutts TM; Rowland IR; Alldrick AJ
Mutat Res; 1992 Oct; 269(2):279-84. PubMed ID: 1383712
[TBL] [Abstract][Full Text] [Related]
27. Species differences in the biotransformation of the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by hepatic microsomes and cytosols from humans, rats, and mice.
Lin DX; Lang NP; Kadlubar FF
Drug Metab Dispos; 1995 Apr; 23(4):518-24. PubMed ID: 7600922
[TBL] [Abstract][Full Text] [Related]
28. Genotoxicity of the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP): formation of 2-hydroxamino-PhIP, a directly acting genotoxic metabolite.
Holme JA; Wallin H; Brunborg G; Søderlund EJ; Hongslo JK; Alexander J
Carcinogenesis; 1989 Aug; 10(8):1389-96. PubMed ID: 2665964
[TBL] [Abstract][Full Text] [Related]
29. The inhibition by flavonoids of 2-amino-3-methylimidazo[4,5-f]quinoline metabolic activation to a mutagen: a structure-activity relationship study.
Edenharder R; Rauscher R; Platt KL
Mutat Res; 1997 Sep; 379(1):21-32. PubMed ID: 9330619
[TBL] [Abstract][Full Text] [Related]
30. Differential metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in rat and human hepatocytes.
Langouët S; Paehler A; Welti DH; Kerriguy N; Guillouzo A; Turesky RJ
Carcinogenesis; 2002 Jan; 23(1):115-22. PubMed ID: 11756232
[TBL] [Abstract][Full Text] [Related]
31. Hydrogen peroxide supports human and rat cytochrome P450 1A2-catalyzed 2-amino-3-methylimidazo[4,5-f]quinoline bioactivation to mutagenic metabolites: significance of cytochrome P450 peroxygenase.
Anari MR; Josephy PD; Henry T; O'Brien PJ
Chem Res Toxicol; 1997 May; 10(5):582-8. PubMed ID: 9168257
[TBL] [Abstract][Full Text] [Related]
32. Human hepatic CYP1A1 and CYP1A2 content, determined with specific anti-peptide antibodies, correlates with the mutagenic activation of PhIP.
Murray BP; Edwards RJ; Murray S; Singleton AM; Davies DS; Boobis AR
Carcinogenesis; 1993 Apr; 14(4):585-92. PubMed ID: 8472319
[TBL] [Abstract][Full Text] [Related]
33. Activation and effects of the food-derived heterocyclic amines in extrahepatic tissues.
Overvik E; Hellmold H; Branting C; Gustafsson JA
Princess Takamatsu Symp; 1995; 23():123-33. PubMed ID: 8844803
[TBL] [Abstract][Full Text] [Related]
34. Species difference among experimental rodents in induction of P450IA family enzymes by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Degawa M; Kobayashi K; Miura S; Arai H; Esumi H; Sugimura T; Hashimoto Y
Jpn J Cancer Res; 1992 Oct; 83(10):1047-51. PubMed ID: 1452456
[TBL] [Abstract][Full Text] [Related]
35. Metabolism of the food derived mutagen and carcinogen 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine (PhIP) by human liver microsomes.
Zhao K; Murray S; Davies DS; Boobis AR; Gooderham NJ
Carcinogenesis; 1994 Jun; 15(6):1285-8. PubMed ID: 8020169
[TBL] [Abstract][Full Text] [Related]
36. The impact of glucuronidation on the bioactivation and DNA adduction of the cooked-food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in vivo.
Malfatti MA; Ubick EA; Felton JS
Carcinogenesis; 2005 Nov; 26(11):2019-28. PubMed ID: 15944213
[TBL] [Abstract][Full Text] [Related]
37. Metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) by liver microsomes and isolated rabbit cytochrome P450 isozymes.
Turteltaub KW; Knize MG; Buonarati MH; McManus ME; Veronese ME; Mazrimas JA; Felton JS
Carcinogenesis; 1990 Jun; 11(6):941-6. PubMed ID: 2347068
[TBL] [Abstract][Full Text] [Related]
38. Effects of the food mutagens MeIQx and PhIP on the expression of cytochrome P450IA proteins in various tissues of male and female rats.
Kleman M; Overvik E; Mason G; Gustafsson JA
Carcinogenesis; 1990 Dec; 11(12):2185-9. PubMed ID: 1702369
[TBL] [Abstract][Full Text] [Related]
39. The direct glucuronidation of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) by human and rabbit liver microsomes.
Styczynski PB; Blackmon RC; Groopman JD; Kensler TW
Chem Res Toxicol; 1993; 6(6):846-51. PubMed ID: 8117924
[TBL] [Abstract][Full Text] [Related]
40. Metabolic activation and cytogenetic effects of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) in Chinese hamster ovary cells expressing murine cytochrome P450 IA2.
Buonarati MH; Tucker JD; Minkler JL; Wu RW; Thompson LH; Felton JS
Mutagenesis; 1991 Jul; 6(4):253-9. PubMed ID: 1943715
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]