250 related articles for article (PubMed ID: 8364921)
21. Cytotoxicity of floxuridine and 5-fluorouracil in human T-lymphoblast leukemia cells: enhancement by leucovorin.
Mini E; Moroson BA; Bertino JR
Cancer Treat Rep; 1987 Apr; 71(4):381-9. PubMed ID: 2950995
[TBL] [Abstract][Full Text] [Related]
22. 5-Ethoxy-2'-deoxyuridine, a novel substrate for thymidine phosphorylase, potentiates the antitumor activity of 5-fluorouracil when used in combination with interferon, an inducer of thymidine phosphorylase expression.
Schwartz EL; Baptiste N; Megati S; Wadler S; Otter BA
Cancer Res; 1995 Aug; 55(16):3543-50. PubMed ID: 7627962
[TBL] [Abstract][Full Text] [Related]
23. Biochemical and pharmacologic basis for potentiation of 5-fluorouracil action by leucovorin.
Rustum YM; Trave F; Zakrzewski SF; Petrelli N; Herrera L; Mittelman A; Arbuck SG; Creaven PJ
NCI Monogr; 1987; (5):165-70. PubMed ID: 2448653
[TBL] [Abstract][Full Text] [Related]
24. Effect of folinic acid on fluorouracil activity and expression of thymidylate synthase.
van der Wilt CL; Pinedo HM; Smid K; Cloos J; Noordhuis P; Peters GJ
Semin Oncol; 1992 Apr; 19(2 Suppl 3):16-25. PubMed ID: 1532671
[TBL] [Abstract][Full Text] [Related]
25. In vitro enhancement of fluoropyrimidine-induced cytotoxicity by leucovorin in colorectal and gastric carcinoma cell lines but not in non-small-cell lung carcinoma cell lines.
Sugimoto Y; Ohe Y; Nishio K; Ohmori T; Fujiwara Y; Saijo N
Cancer Chemother Pharmacol; 1992; 30(6):417-22. PubMed ID: 1327567
[TBL] [Abstract][Full Text] [Related]
26. Phase I trial of 5-fluorouracil and recombinant alpha 2a-interferon in patients with advanced colorectal carcinoma.
Wadler S; Goldman M; Lyver A; Wiernik PH
Cancer Res; 1990 Apr; 50(7):2056-9. PubMed ID: 2317795
[TBL] [Abstract][Full Text] [Related]
27. Novel mechanism(s) of resistance to 5-fluorouracil in human colon cancer (HCT-8) sublines following exposure to two different clinically relevant dose schedules.
Aschele C; Sobrero A; Faderan MA; Bertino JR
Cancer Res; 1992 Apr; 52(7):1855-64. PubMed ID: 1532346
[TBL] [Abstract][Full Text] [Related]
28. Mechanism of cell death following thymidylate synthase inhibition: 2'-deoxyuridine-5'-triphosphate accumulation, DNA damage, and growth inhibition following exposure to CB3717 and dipyridamole.
Curtin NJ; Harris AL; Aherne GW
Cancer Res; 1991 May; 51(9):2346-52. PubMed ID: 2015598
[TBL] [Abstract][Full Text] [Related]
29. Pharmacologic rationale for fluoropyrimidine-leucovorin combination: biochemical mechanisms.
Zhang ZG; Rustum YM
Semin Oncol; 1992 Apr; 19(2 Suppl 4):46-50. PubMed ID: 1532459
[TBL] [Abstract][Full Text] [Related]
30. Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines.
van Triest B; Pinedo HM; van Hensbergen Y; Smid K; Telleman F; Schoenmakers PS; van der Wilt CL; van Laar JA; Noordhuis P; Jansen G; Peters GJ
Clin Cancer Res; 1999 Mar; 5(3):643-54. PubMed ID: 10100718
[TBL] [Abstract][Full Text] [Related]
31. Biochemical mechanisms of interferon modulation of 5-fluorouracil activity in colon cancer cells.
van der Wilt CL; Smid K; Aherne GW; Noordhuis P; Peters GJ
Eur J Cancer; 1997 Mar; 33(3):471-8. PubMed ID: 9155534
[TBL] [Abstract][Full Text] [Related]
32. Combination cytotoxic effects of cis-diamminedichloroplatinum(II) and 5-fluorouracil with and without leucovorin against human non-small cell lung cancer cell lines.
Tsai CM; Hsiao SH; Frey CM; Chang KT; Perng RP; Gazdar AF; Kramer BS
Cancer Res; 1993 Mar; 53(5):1079-84. PubMed ID: 8382553
[TBL] [Abstract][Full Text] [Related]
33. The efficacy of the combination therapy of 5-fluorouracil, cisplatin and leucovorin for hepatocellular carcinoma and its predictable factors.
Kogure T; Ueno Y; Iwasaki T; Shimosegawa T
Cancer Chemother Pharmacol; 2004 Apr; 53(4):296-304. PubMed ID: 14689231
[TBL] [Abstract][Full Text] [Related]
34. 5-Fluorouracil enhances azidothymidine cytotoxicity: in vitro, in vivo, and biochemical studies.
Brunetti I; Falcone A; Calabresi P; Goulette FA; Darnowski JW
Cancer Res; 1990 Jul; 50(13):4026-31. PubMed ID: 2354452
[TBL] [Abstract][Full Text] [Related]
35. Thymidylate synthase protein expression: Association with response to neoadjuvant chemotherapy and resection for locally advanced gastric and gastroesophageal adenocarcinoma.
Alexander HR; Grem JL; Hamilton JM; Pass HI; Hong M; Fraker DL; Steinberg SM; McAtee N; Allegra BC; Johnston PG
Cancer J Sci Am; 1995; 1(1):49-54. PubMed ID: 9166454
[TBL] [Abstract][Full Text] [Related]
36. Dependence of 5-fluorouracil-mediated radiosensitization on DNA-directed effects.
Lawrence TS; Davis MA; Maybaum J
Int J Radiat Oncol Biol Phys; 1994 Jun; 29(3):519-23. PubMed ID: 8005809
[TBL] [Abstract][Full Text] [Related]
37. Relationship between dose rate of [6RS]Leucovorin administration, plasma concentrations of reduced folates, and pools of 5,10-methylenetetrahydrofolates and tetrahydrofolates in human colon adenocarcinoma xenografts.
Houghton JA; Williams LG; de Graaf SS; Cheshire PJ; Rodman JH; Maneval DC; Wainer IW; Jadaud P; Houghton PJ
Cancer Res; 1990 Jun; 50(12):3493-502. PubMed ID: 2140289
[TBL] [Abstract][Full Text] [Related]
38. Contrasting patterns of DNA fragmentation induced by thymidylate synthase inhibitors, ZD1694 and AG-331.
Panadero A; Yin MB; Voigt W; Rustum YM
Oncol Res; 1995; 7(2):73-81. PubMed ID: 7579730
[TBL] [Abstract][Full Text] [Related]
39. The role of interferon-alpha as a modulator of fluorouracil and leucovorin.
Grem JL; van Groeningen CJ; Ismail AA; Johnston PG; Alexander HR; Allegra CJ
Eur J Cancer; 1995; 31A(7-8):1316-20. PubMed ID: 7577043
[TBL] [Abstract][Full Text] [Related]
40. Selective protection by uridine of growth inhibition by 5-fluorouracil (5FU) mediated by 5FU incorporation into RNA, but not the thymidylate synthase mediated growth inhibition by 5FU-leucovorin.
Codacci-Pisanelli G; Noordhuis P; van der Wilt CL; Peters GJ
Nucleosides Nucleotides Nucleic Acids; 2008 Jun; 27(6):733-9. PubMed ID: 18600533
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]