These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

358 related articles for article (PubMed ID: 8374050)

  • 1. Cytochrome P450 enzymes involved in acetaminophen activation by rat and human liver microsomes and their kinetics.
    Patten CJ; Thomas PE; Guy RL; Lee M; Gonzalez FJ; Guengerich FP; Yang CS
    Chem Res Toxicol; 1993; 6(4):511-8. PubMed ID: 8374050
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of flavonoids on cytochrome P450-dependent acetaminophen metabolism in rats and human liver microsomes.
    Li Y; Wang E; Patten CJ; Chen L; Yang CS
    Drug Metab Dispos; 1994; 22(4):566-71. PubMed ID: 7956731
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Kinetic analysis of the activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by heterologously expressed human P450 enzymes and the effect of P450-specific chemical inhibitors on this activation in human liver microsomes.
    Patten CJ; Smith TJ; Murphy SE; Wang MH; Lee J; Tynes RE; Koch P; Yang CS
    Arch Biochem Biophys; 1996 Sep; 333(1):127-38. PubMed ID: 8806763
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Acetaminophen activation by human liver cytochromes P450IIE1 and P450IA2.
    Raucy JL; Lasker JM; Lieber CS; Black M
    Arch Biochem Biophys; 1989 Jun; 271(2):270-83. PubMed ID: 2729995
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 7-Ethoxycoumarin O-deethylation catalyzed by cytochromes P450 1A2 and 2E1 in human liver microsomes.
    Yamazaki H; Inoue K; Mimura M; Oda Y; Guengerich FP; Shimada T
    Biochem Pharmacol; 1996 Feb; 51(3):313-9. PubMed ID: 8573198
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human lung and liver microsomes and cytochromes P-450 expressed in hepatoma cells.
    Smith TJ; Guo Z; Gonzalez FJ; Guengerich FP; Stoner GD; Yang CS
    Cancer Res; 1992 Apr; 52(7):1757-63. PubMed ID: 1312898
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of the human liver microsomal cytochrome P450s involved in the metabolism of N-nitrosodi-n-propylamine.
    Teiber JF; Hollenberg PF
    Carcinogenesis; 2000 Aug; 21(8):1559-66. PubMed ID: 10910959
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A monoclonal antibody inhibitory to human P450 2D6: a paradigm for use in combinatorial determination of individual P450 role in specific drug tissue metabolism.
    Gelboin HV; Krausz KW; Shou M; Gonzalez FJ; Yang TJ
    Pharmacogenetics; 1997 Dec; 7(6):469-77. PubMed ID: 9429232
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Catalytic role of cytochrome P4502B6 in the N-demethylation of S-mephenytoin.
    Heyn H; White RB; Stevens JC
    Drug Metab Dispos; 1996 Sep; 24(9):948-54. PubMed ID: 8886603
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evidence for cytochrome P450 2A6 and 3A4 as major catalysts for N'-nitrosonornicotine alpha-hydroxylation by human liver microsomes.
    Patten CJ; Smith TJ; Friesen MJ; Tynes RE; Yang CS; Murphy SE
    Carcinogenesis; 1997 Aug; 18(8):1623-30. PubMed ID: 9276639
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes.
    Yamazaki H; Guo Z; Persmark M; Mimura M; Inoue K; Guengerich FP; Shimada T
    Mol Pharmacol; 1994 Sep; 46(3):568-77. PubMed ID: 7935340
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sex-related differences in mouse renal metabolism and toxicity of acetaminophen.
    Hu JJ; Lee MJ; Vapiwala M; Reuhl K; Thomas PE; Yang CS
    Toxicol Appl Pharmacol; 1993 Sep; 122(1):16-26. PubMed ID: 8378930
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Catalytic properties of the human cytochrome P450 2E1 produced by cDNA expression in mammalian cells.
    Patten CJ; Ishizaki H; Aoyama T; Lee M; Ning SM; Huang W; Gonzalez FJ; Yang CS
    Arch Biochem Biophys; 1992 Nov; 299(1):163-71. PubMed ID: 1444447
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interaction of caffeine with acetaminophen. 1. Correlation of the effect of caffeine on acetaminophen hepatotoxicity and acetaminophen bioactivation following treatment of mice with various cytochrome P450 inducing agents.
    Jaw S; Jeffery EH
    Biochem Pharmacol; 1993 Aug; 46(3):493-501. PubMed ID: 8347173
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human liver microsomes are efficient catalysts of 1,3-butadiene oxidation: evidence for major roles by cytochromes P450 2A6 and 2E1.
    Duescher RJ; Elfarra AA
    Arch Biochem Biophys; 1994 Jun; 311(2):342-9. PubMed ID: 8203896
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Metabolism of 5-methylchrysene and 6-methylchrysene by human hepatic and pulmonary cytochrome P450 enzymes.
    Koehl W; Amin S; Staretz ME; Ueng YF; Yamazaki H; Tateishi T; Guengerich FP; Hecht SS
    Cancer Res; 1996 Jan; 56(2):316-24. PubMed ID: 8542586
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Involvement of human cytochrome P450 2D6 in the bioactivation of acetaminophen.
    Dong H; Haining RL; Thummel KE; Rettie AE; Nelson SD
    Drug Metab Dispos; 2000 Dec; 28(12):1397-400. PubMed ID: 11095574
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hydroxymethylvinyl ketone: a reactive Michael acceptor formed by the oxidation of 3-butene-1,2-diol by cDNA-expressed human cytochrome P450s and mouse, rat, and human liver microsomes.
    Krause RJ; Kemper RA; Elfarra AA
    Chem Res Toxicol; 2001 Dec; 14(12):1590-5. PubMed ID: 11743741
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of human hepatic cytochrome P450 1A2 and 3A4 in the metabolic activation of estrone.
    Shou M; Korzekwa KR; Brooks EN; Krausz KW; Gonzalez FJ; Gelboin HV
    Carcinogenesis; 1997 Jan; 18(1):207-14. PubMed ID: 9054608
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Selective biotransformation of taxol to 6 alpha-hydroxytaxol by human cytochrome P450 2C8.
    Rahman A; Korzekwa KR; Grogan J; Gonzalez FJ; Harris JW
    Cancer Res; 1994 Nov; 54(21):5543-6. PubMed ID: 7923194
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.