BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

192 related articles for article (PubMed ID: 8385105)

  • 1. The insulin and insulin-like growth factor-I receptor substrate IRS-1 associates with and activates phosphatidylinositol 3-kinase in vitro.
    Giorgetti S; Ballotti R; Kowalski-Chauvel A; Tartare S; Van Obberghen E
    J Biol Chem; 1993 Apr; 268(10):7358-64. PubMed ID: 8385105
    [TBL] [Abstract][Full Text] [Related]  

  • 2. IRS-1 is a common element in insulin and insulin-like growth factor-I signaling to the phosphatidylinositol 3'-kinase.
    Myers MG; Sun XJ; Cheatham B; Jachna BR; Glasheen EM; Backer JM; White MF
    Endocrinology; 1993 Apr; 132(4):1421-30. PubMed ID: 8384986
    [TBL] [Abstract][Full Text] [Related]  

  • 3. IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85.
    Myers MG; Backer JM; Sun XJ; Shoelson S; Hu P; Schlessinger J; Yoakim M; Schaffhausen B; White MF
    Proc Natl Acad Sci U S A; 1992 Nov; 89(21):10350-4. PubMed ID: 1332046
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tyrosine residues in the C-terminal domain of the insulin-like growth factor-I receptor mediate mitogenic and tumorigenic signals.
    Esposito DL; Blakesley VA; Koval AP; Scrimgeour AG; LeRoith D
    Endocrinology; 1997 Jul; 138(7):2979-88. PubMed ID: 9202243
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phosphatidylinositol 3'-kinase is activated by association with IRS-1 during insulin stimulation.
    Backer JM; Myers MG; Shoelson SE; Chin DJ; Sun XJ; Miralpeix M; Hu P; Margolis B; Skolnik EY; Schlessinger J
    EMBO J; 1992 Sep; 11(9):3469-79. PubMed ID: 1380456
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Muscarinic-receptor-mediated inhibition of insulin-like growth factor-1 receptor-stimulated phosphoinositide 3-kinase signalling in 1321N1 astrocytoma cells.
    Batty IH; Fleming IN; Downes CP
    Biochem J; 2004 May; 379(Pt 3):641-51. PubMed ID: 14769130
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Insulin-like growth factor induces phosphorylation of immunoreactive insulin receptor substrate and its association with phosphatidylinositol-3 kinase in human thymocytes.
    Kooijman R; Lauf JJ; Kappers AC; Rijkers GT
    J Exp Med; 1995 Aug; 182(2):593-7. PubMed ID: 7543144
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Insulin and interleukin-4 induce desensitization to the mitogenic effects of insulin-like growth factor-I. Pivotal role for insulin receptor substrate-2.
    Haddad TC; Conover CA
    J Biol Chem; 1997 Aug; 272(31):19525-31. PubMed ID: 9235956
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Insulin-stimulated oocyte maturation requires insulin receptor substrate 1 and interaction with the SH2 domains of phosphatidylinositol 3-kinase.
    Chuang LM; Myers MG; Backer JM; Shoelson SE; White MF; Birnbaum MJ; Kahn CR
    Mol Cell Biol; 1993 Nov; 13(11):6653-60. PubMed ID: 8413261
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Insulin-like growth factor-1 (IGF-1) receptor-insulin receptor substrate complexes in the uterus. Altered signaling response to estradiol in the IGF-1(m/m) mouse.
    Richards RG; Walker MP; Sebastian J; DiAugustine RP
    J Biol Chem; 1998 May; 273(19):11962-9. PubMed ID: 9565625
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Association of IRS-1 with the insulin receptor and the phosphatidylinositol 3'-kinase. Formation of binary and ternary signaling complexes in intact cells.
    Backer JM; Myers MG; Sun XJ; Chin DJ; Shoelson SE; Miralpeix M; White MF
    J Biol Chem; 1993 Apr; 268(11):8204-12. PubMed ID: 8385139
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential signaling by insulin receptor substrate 1 (IRS-1) and IRS-2 in IRS-1-deficient cells.
    BrĂ¼ning JC; Winnay J; Cheatham B; Kahn CR
    Mol Cell Biol; 1997 Mar; 17(3):1513-21. PubMed ID: 9032279
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Association of the insulin receptor and phosphatidylinositol 3-kinase requires a third component.
    Liu R; Livingston JN
    Biochem J; 1994 Jan; 297 ( Pt 2)(Pt 2):335-42. PubMed ID: 8297340
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Involvement of Src-homology/collagen (SHC) proteins in signaling through the insulin receptor and the insulin-like-growth-factor-I-receptor.
    Giorgetti S; Pelicci PG; Pelicci G; Van Obberghen E
    Eur J Biochem; 1994 Jul; 223(1):195-202. PubMed ID: 8033892
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mammalian target of rapamycin inhibitors activate the AKT kinase in multiple myeloma cells by up-regulating the insulin-like growth factor receptor/insulin receptor substrate-1/phosphatidylinositol 3-kinase cascade.
    Shi Y; Yan H; Frost P; Gera J; Lichtenstein A
    Mol Cancer Ther; 2005 Oct; 4(10):1533-40. PubMed ID: 16227402
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Potent activation of phosphatidylinositol 3'-kinase by simple phosphotyrosine peptides derived from insulin receptor substrate 1 containing two YMXM motifs for binding SH2 domains.
    Herbst JJ; Andrews G; Contillo L; Lamphere L; Gardner J; Lienhard GE; Gibbs EM
    Biochemistry; 1994 Aug; 33(32):9376-81. PubMed ID: 7520748
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Common and distinct elements in insulin and PDGF signaling.
    Myers MG; Cheatham B; Fisher TL; Jachna BR; Kahn CR; Backer JM; White MF
    Ann N Y Acad Sci; 1995 Sep; 766():369-87. PubMed ID: 7486683
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Different effects of insulin and platelet-derived growth factor on phosphatidylinositol 3-kinase at the subcellular level in 3T3-L1 adipocytes. A possible explanation for their specific effects on glucose transport.
    Ricort JM; Tanti JF; Van Obberghen E; Le Marchand-Brustel Y
    Eur J Biochem; 1996 Jul; 239(1):17-22. PubMed ID: 8706703
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The insulin-elicited 60-kDa phosphotyrosine protein in rat adipocytes is associated with phosphatidylinositol 3-kinase.
    Lavan BE; Lienhard GE
    J Biol Chem; 1993 Mar; 268(8):5921-8. PubMed ID: 7680652
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Insulin receptor substrate (IRS) proteins IRS-1 and IRS-2 differential signaling in the insulin/insulin-like growth factor-I pathways in fetal brown adipocytes.
    Valverde AM; Lorenzo M; Pons S; White MF; Benito M
    Mol Endocrinol; 1998 May; 12(5):688-97. PubMed ID: 9605931
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.