These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 8385331)

  • 1. Antitumor agents. 126. Novel 4 beta-substituted anilino derivatives of 3',4'-O,O-didemethylpodophyllotoxin as potent inhibitors of human DNA topoisomerase II.
    Wang ZQ; Shen YC; Chen HX; Chang JY; Guo X; Cheng YC; Lee KH
    Pharm Res; 1993 Mar; 10(3):343-50. PubMed ID: 8385331
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Antitumor agents. 113. New 4 beta-arylamino derivatives of 4'-O-demethylepipodophyllotoxin and related compounds as potent inhibitors of human DNA topoisomerase II.
    Wang ZQ; Kuo YH; Schnur D; Bowen JP; Liu SY; Han FS; Chang JY; Cheng YC; Lee KH
    J Med Chem; 1990 Sep; 33(9):2660-6. PubMed ID: 2167985
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Antitumor agents. 124. New 4 beta-substituted aniline derivatives of 6,7-O,O-demethylene-4'-O-demethylpodophyllotoxin and related compounds as potent inhibitors of human DNA topoisomerase II.
    Wang ZQ; Hu H; Chen HX; Cheng YC; Lee KH
    J Med Chem; 1992 Mar; 35(5):871-7. PubMed ID: 1312601
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antitumor agents. 125. New 4 beta-benzoylamino derivatives of 4'-O-demethyl-4-desoxypodophyllotoxin and 4 beta-benzoyl derivatives of 4'-O-demethylpodophyllotoxin as potent inhibitors of human DNA topoisomerase II.
    Zhou XM; Wang ZQ; Chen HX; Cheng YC; Lee KH
    Pharm Res; 1993 Feb; 10(2):214-9. PubMed ID: 8384366
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antitumor agents. 111. New 4-hydroxylated and 4-halogenated anilino derivatives of 4'-demethylepipodophyllotoxin as potent inhibitors of human DNA topoisomerase II.
    Lee KH; Beers SA; Mori M; Wang ZQ; Kuo YH; Li L; Liu SY; Chang JY; Han FS; Cheng YC
    J Med Chem; 1990 May; 33(5):1364-8. PubMed ID: 2158562
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antitumor agents. 120. New 4-substituted benzylamine and benzyl ether derivatives of 4'-O-demethylepipodophyllotoxin as potent inhibitors of human DNA topoisomerase II.
    Zhou XM; Wang ZQ; Chang JY; Chen HX; Cheng YC; Lee KH
    J Med Chem; 1991 Dec; 34(12):3346-50. PubMed ID: 1662724
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Antitumor agents, 107. New cytotoxic 4-alkylamino analogues of 4'-demethyl-epipodophyllotoxin as inhibitors of human DNA topoisomerase II.
    Lee KH; Imakura Y; Haruna M; Beers SA; Thurston LS; Dai HJ; Chen CH; Liu SY; Cheng YC
    J Nat Prod; 1989; 52(3):606-13. PubMed ID: 2550587
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antitumor agents, 130, Novel 4 beta-arylamino derivatives of 3',4'-didemethoxy-3',4'-dioxo-4-deoxypodophyllotoxin as potent inhibitors of human DNA topoisomerase II.
    Zhang YL; Shen YC; Wang ZQ; Chen HX; Guo X; Cheng YC; Lee KH
    J Nat Prod; 1992 Aug; 55(8):1100-11. PubMed ID: 1331331
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antitumor agents. 123. Synthesis and human DNA topoisomerase II inhibitory activity of 2'-chloro derivatives of etoposide and 4 beta-(arylamino)-4'-O-demethylpodophyllotoxins.
    Hu H; Wang ZQ; Liu SY; Cheng YC; Lee KH
    J Med Chem; 1992 Mar; 35(5):866-71. PubMed ID: 1312600
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel carbamate derivatives of 4-beta-amino-4'-O-demethyl-4-desoxypodophyllotoxin as inhibitors of topoisomerase II: synthesis and biological evaluation.
    Duca M; Arimondo PB; Léonce S; Pierré A; Pfeiffer B; Monneret C; Dauzonne D
    Org Biomol Chem; 2005 Mar; 3(6):1074-80. PubMed ID: 15750651
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Antitumor agents. 194. Synthesis and biological evaluations of 4-beta-mono-, -di-, and -trisubstituted aniline-4'-O-demethyl-podophyllotoxin and related compounds with improved pharmacological profiles.
    Zhu XK; Guan J; Tachibana Y; Bastow KF; Cho SJ; Cheng HH; Cheng YC; Gurwith M; Lee KH
    J Med Chem; 1999 Jul; 42(13):2441-6. PubMed ID: 10395485
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antitumor agents. 164. Podophenazine, 2'',3''-dichloropodophenazine, benzopodophenazine, and their 4 beta-p-nitroaniline derivatives as novel DNA topoisomerase II inhibitors.
    Cho SJ; Kashiwada Y; Bastow KF; Cheng YC; Lee KH
    J Med Chem; 1996 Mar; 39(7):1396-402. PubMed ID: 8691469
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of 4 beta-arylamino derivatives of 4'-O-demethylepipodophyllotoxin on human DNA topoisomerase II, tubulin polymerization, KB cells, and their resistant variants.
    Chang JY; Han FS; Liu SY; Wang ZQ; Lee KH; Cheng YC
    Cancer Res; 1991 Apr; 51(7):1755-9. PubMed ID: 1848478
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antitumor agents. 100. Inhibition of human DNA topoisomerase II by cytotoxic ether and ester derivatives of podophyllotoxin and alpha-peltatin.
    Thurston LS; Imakura Y; Haruna M; Li DH; Liu ZC; Liu SY; Cheng YC; Lee KH
    J Med Chem; 1989 Mar; 32(3):604-8. PubMed ID: 2537424
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antitumor agents. Part 227: Studies on novel 4'-O-demethyl-epipodophyllotoxins as antitumor agents targeting topoisomerase II.
    Xiao Z; Bastow KF; Vance JR; Lee KH
    Bioorg Med Chem; 2004 Jun; 12(12):3339-44. PubMed ID: 15158802
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Antitumor agents. 3. Synthesis and biological activity of 4 beta-alkyl derivatives containing hydroxy, amino, and amido groups of 4'-O-demethyl-4-desoxypodophyllotoxin as antitumor agents.
    Terada T; Fujimoto K; Nomura M; Yamashita J; Wierzba K; Yamazaki R; Shibata J; Sugimoto Y; Yamada Y; Kobunai T
    J Med Chem; 1993 Jun; 36(12):1689-99. PubMed ID: 8389875
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antitumor agents. I. DNA topoisomerase II inhibitory activity and the structural relationship of podophyllotoxin derivatives as antitumor agents.
    Terada T; Fujimoto K; Nomura M; Yamashita J; Kobunai T; Takeda S; Wierzba K; Yamada Y; Yamaguchi H
    Chem Pharm Bull (Tokyo); 1992 Oct; 40(10):2720-7. PubMed ID: 1334447
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Antitumor agents. 234. Design, synthesis, and biological evaluation of novel 4beta-[(4' '-benzamido)-amino]-4'-o-demethyl-epipodophyllotoxin derivatives.
    Xiao Z; Bastow KF; Vance JR; Sidwell RS; Wang HK; Chen MS; Shi Q; Lee KH
    J Med Chem; 2004 Oct; 47(21):5140-8. PubMed ID: 15456257
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antitumor agents, 99. Synthetic ring C aromatized podophyllotoxin analogues as potential inhibitors of human DNA topoisomerase II.
    Beers SA; Imakura Y; Dai HJ; Li DH; Cheng YC; Lee KH
    J Nat Prod; 1988; 51(5):901-5. PubMed ID: 2849640
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Antitumor agents. 78. Inhibition of human DNA topoisomerase II by podophyllotoxin and alpha-peltatin analogues.
    Thurston LS; Irie H; Tani S; Han FS; Liu ZC; Cheng YC; Lee KH
    J Med Chem; 1986 Aug; 29(8):1547-50. PubMed ID: 3016271
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.