BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

96 related articles for article (PubMed ID: 8386514)

  • 1. Chimeric oligodeoxynucleotide analogues: enhanced cell uptake of structures which direct ribonuclease H with high specificity.
    Giles RV; Spiller DG; Tidd DM
    Anticancer Drug Des; 1993 Feb; 8(1):33-51. PubMed ID: 8386514
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Enhanced RNase H activity with methylphosphonodiester/phosphodiester chimeric antisense oligodeoxynucleotides.
    Giles RV; Tidd DM
    Anticancer Drug Des; 1992 Feb; 7(1):37-48. PubMed ID: 1311929
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The uptake kinetics of chimeric oligodeoxynucleotide analogues in human leukaemia MOLT-4 cells.
    Spiller DG; Tidd DM
    Anticancer Drug Des; 1992 Apr; 7(2):115-29. PubMed ID: 1575885
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Increased specificity for antisense oligodeoxynucleotide targeting of RNA cleavage by RNase H using chimeric methylphosphonodiester/phosphodiester structures.
    Giles RV; Tidd DM
    Nucleic Acids Res; 1992 Feb; 20(4):763-70. PubMed ID: 1371864
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phosphorothioate oligonucleotides block reverse transcription by the Rnase H activity associated with the HIV-1 polymerase.
    Hatta T; Takai K; Yokoyama S; Nakashima H; Yamamoto N; Takaku H
    Biochem Biophys Res Commun; 1995 Jun; 211(3):1041-6. PubMed ID: 7541196
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphorothioate oligonucleotides are inhibitors of human DNA polymerases and RNase H: implications for antisense technology.
    Gao WY; Han FS; Storm C; Egan W; Cheng YC
    Mol Pharmacol; 1992 Feb; 41(2):223-9. PubMed ID: 1371582
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Antisense phosphorothioate oligonucleotides direct both site-specific and nonspecific RNAse H cleavage of in vitro synthesized p120 mRNA.
    Weidner DA; Busch H
    Oncol Res; 1994; 6(6):237-42. PubMed ID: 7865899
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of HIV-1 replication by a new type of circular dumbbell RNA/DNA chimeric oligonucleotides.
    Park WS; Miyano-Kurosaki N; Abe T; Takai K; Yamamoto N; Takaku H
    Biochem Biophys Res Commun; 2000 Apr; 270(3):953-60. PubMed ID: 10772932
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of expression of the multidrug resistance-associated P-glycoprotein of by phosphorothioate and 5' cholesterol-conjugated phosphorothioate antisense oligonucleotides.
    Alahari SK; Dean NM; Fisher MH; Delong R; Manoharan M; Tivel KL; Juliano RL
    Mol Pharmacol; 1996 Oct; 50(4):808-19. PubMed ID: 8863825
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Single base discrimination for ribonuclease H-dependent antisense effects within intact human leukaemia cells.
    Giles RV; Ruddell CJ; Spiller DG; Green JA; Tidd DM
    Nucleic Acids Res; 1995 Mar; 23(6):954-61. PubMed ID: 7731809
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Optimization of antisense oligodeoxynucleotide structure for targeting bcr-abl mRNA.
    Giles RV; Spiller DG; Green JA; Clark RE; Tidd DM
    Blood; 1995 Jul; 86(2):744-54. PubMed ID: 7606003
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Conjugation of an antisense oligodeoxynucleotide to ribonuclease h results in sequence-specific cleavage and intracellular inhibition of HCV gene expression.
    Fukuma T; Walton CM; Wu CH; Wu GY
    Bioconjug Chem; 2003; 14(2):295-301. PubMed ID: 12643739
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The influence of target protein half-life on the effectiveness of antisense oligonucleotide analog-mediated biologic responses.
    Spiller DG; Giles RV; Broughton CM; Grzybowski J; Ruddell CJ; Tidd DM; Clark RE
    Antisense Nucleic Acid Drug Dev; 1998 Aug; 8(4):281-93. PubMed ID: 9743466
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and anti-influenza virus-A activity of circular dumbbell RNA DNA chimeric oligonucleotides.
    Abe T; Hatta T; Yamakawa H; Takai K; Yokota T; Takaku H
    Nucleic Acids Symp Ser; 1997; (37):219-20. PubMed ID: 9586078
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Site-specific excision from RNA by RNase H and mixed-phosphate-backbone oligodeoxynucleotides.
    Agrawal S; Mayrand SH; Zamecnik PC; Pederson T
    Proc Natl Acad Sci U S A; 1990 Feb; 87(4):1401-5. PubMed ID: 2154746
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Potent and selective inhibition of gene expression by an antisense heptanucleotide.
    Wagner RW; Matteucci MD; Grant D; Huang T; Froehler BC
    Nat Biotechnol; 1996 Jul; 14(7):840-4. PubMed ID: 9631007
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antisense gene inhibition by C-5-substituted deoxyuridine-containing oligodeoxynucleotides.
    Gutierrez AJ; Matteucci MD; Grant D; Matsumura S; Wagner RW; Froehler BC
    Biochemistry; 1997 Jan; 36(4):743-8. PubMed ID: 9020771
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A nonantisense sequence-selective effect of a phosphorothioate oligodeoxynucleotide directed against the epidermal growth factor receptor in A431 cells.
    Coulson JM; Poyner DR; Chantry A; Irwin WJ; Akhtar S
    Mol Pharmacol; 1996 Aug; 50(2):314-25. PubMed ID: 8700139
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Selective binding of trisamine-modified phosphorothioate antisense DNA to target mRNA improves antisense activity and reduces toxicity.
    Matsukura M; Okamoto T; Miike T; Sawai H; Shinozuka K
    Biochem Biophys Res Commun; 2002 May; 293(5):1341-7. PubMed ID: 12054660
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A phosphorothioate oligonucleotide blocks reverse transcription via an antisense mechanism.
    Boiziau C; Moreau S; Toulmé JJ
    FEBS Lett; 1994 Mar; 340(3):236-40. PubMed ID: 7510640
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.