123 related articles for article (PubMed ID: 8386769)
1. Synthesis and evaluation of imidazo[1,5-a][1,4]benzodiazepine esters with high affinities and selectivities at "diazepam-insensitive" benzodiazepine receptors.
Gu ZQ; Wong G; Dominguez C; de Costa BR; Rice KC; Skolnick P
J Med Chem; 1993 Apr; 36(8):1001-6. PubMed ID: 8386769
[TBL] [Abstract][Full Text] [Related]
2. Synthetic and computer-assisted analysis of the structural requirements for selective, high-affinity ligand binding to diazepam-insensitive benzodiazepine receptors.
Wong G; Koehler KF; Skolnick P; Gu ZQ; Ananthan S; Schönholzer P; Hunkeler W; Zhang W; Cook JM
J Med Chem; 1993 Jun; 36(13):1820-30. PubMed ID: 8390574
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and structure-activity relationships of 3,5-disubstituted 4,5-dihydro-6H-imidazo[1,5-a][1,4]benzodiazepin-6-ones at diazepam-sensitive and diazepam-insensitive benzodiazepine receptors.
Ananthan S; Clayton SD; Ealick SE; Wong G; Evoniuk GE; Skolnick P
J Med Chem; 1993 Feb; 36(4):479-90. PubMed ID: 8386247
[TBL] [Abstract][Full Text] [Related]
4. Synthesis of novel imidazobenzodiazepines as probes of the pharmacophore for "diazepam-insensitive" GABAA receptors.
Zhang P; Zhang W; Liu R; Harris B; Skolnick P; Cook JM
J Med Chem; 1995 May; 38(10):1679-88. PubMed ID: 7752192
[TBL] [Abstract][Full Text] [Related]
5. Labelling of diazepam-sensitive and -insensitive benzodiazepine receptors with [3H]tert-butyl-8-chloro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo [1,5-a][1,4]benzodiazepine 3-carboxylate (ZG-63).
Wong G; Gu ZQ; de Costa B; Skolnick P
Eur J Pharmacol; 1993 Sep; 247(1):57-63. PubMed ID: 8258361
[TBL] [Abstract][Full Text] [Related]
6. High affinity ligands for 'diazepam-insensitive' benzodiazepine receptors.
Wong G; Skolnick P
Eur J Pharmacol; 1992 Jan; 225(1):63-8. PubMed ID: 1311690
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and evaluation of [123I]labelled analogues of the partial inverse agonist Ro 15-4513 for the study of diazepam-insensitive benzodiazepine receptors.
Katsifis A; Mardon K; McPhee M; Mattner F; Dikic B; Ridley D
Nucl Med Biol; 1999 Aug; 26(6):641-9. PubMed ID: 10587102
[TBL] [Abstract][Full Text] [Related]
8. Characterization of novel ligands for wild-type and natural mutant diazepam-insensitive benzodiazepine receptors.
Wong G; Uusi-Oukari M; Hansen HC; Suzdak PD; Korpi ER
Eur J Pharmacol; 1995 Apr; 289(2):335-42. PubMed ID: 7621907
[TBL] [Abstract][Full Text] [Related]
9. Ro 15-4513 binding to GABAA receptors: subunit composition determines ligand efficacy.
Wong G; Skolnick P
Pharmacol Biochem Behav; 1992 May; 42(1):107-10. PubMed ID: 1326771
[TBL] [Abstract][Full Text] [Related]
10. Binding of 1,4-benzodiazepines to a novel [3H]Ro15-4513 binding site in the rat spinal cord.
Maguire PA; Davies MF; Loew GH
Eur J Pharmacol; 1995 Jul; 280(2):167-73. PubMed ID: 7589182
[TBL] [Abstract][Full Text] [Related]
11. Stereospecific transduction of behavioral effects via diazepam-insensitive GABAA receptors.
Acri JB; Wong G; Witkin JM
Eur J Pharmacol; 1995 May; 278(3):213-23. PubMed ID: 7589157
[TBL] [Abstract][Full Text] [Related]
12. Pharmacophore/receptor models for GABA(A)/BzR subtypes (alpha1beta3gamma2, alpha5beta3gamma2, and alpha6beta3gamma2) via a comprehensive ligand-mapping approach.
Huang Q; He X; Ma C; Liu R; Yu S; Dayer CA; Wenger GR; McKernan R; Cook JM
J Med Chem; 2000 Jan; 43(1):71-95. PubMed ID: 10633039
[TBL] [Abstract][Full Text] [Related]
13. Characterization of U-97775 as a GABAA receptor ligand of dual functionality in cloned rat GABAA receptor subtypes.
Im HK; Im WB; Pregenzer JF; Carter DB; Jacobsen EJ; Hamilton BJ
Br J Pharmacol; 1995 May; 115(1):19-24. PubMed ID: 7647975
[TBL] [Abstract][Full Text] [Related]
14. Central benzodiazepine receptors: in vitro efficacies and potencies of 3-substituted 1,4-benzodiazepine stereoisomers.
Maksay G; Tegyey Z; Simonyi M
Mol Pharmacol; 1991 Jun; 39(6):725-32. PubMed ID: 1646947
[TBL] [Abstract][Full Text] [Related]
15. 5-aryl-imidazo[2,1-c][1,4]benzodiazepine derivatives as tricyclic constrained analogues of diazepam and Ro5-4864. Synthesis and binding properties at peripheral and central benzodiazepine receptors.
Rizzetto E; Castellano S; Florio C; Vadori M; Stefancich G
Pharmazie; 2006 Jun; 61(6):505-10. PubMed ID: 16826968
[TBL] [Abstract][Full Text] [Related]
16. [3H]RY 80: A high-affinity, selective ligand for gamma-aminobutyric acidA receptors containing alpha-5 subunits.
Skolnick P; Hu RJ; Cook CM; Hurt SD; Trometer JD; Liu R; Huang Q; Cook JM
J Pharmacol Exp Ther; 1997 Nov; 283(2):488-93. PubMed ID: 9353361
[TBL] [Abstract][Full Text] [Related]
17. The benzodiazepine/alcohol antagonist Ro 15-4513: binding to a GABAA receptor subtype that is insensitive to diazepam.
Turner DM; Sapp DW; Olsen RW
J Pharmacol Exp Ther; 1991 Jun; 257(3):1236-42. PubMed ID: 1646328
[TBL] [Abstract][Full Text] [Related]
18. Cloning and characterization of the human GABAA receptor alpha 4 subunit: identification of a unique diazepam-insensitive binding site.
Yang W; Drewe JA; Lan NC
Eur J Pharmacol; 1995 Nov; 291(3):319-25. PubMed ID: 8719416
[TBL] [Abstract][Full Text] [Related]
19. Characterization of a benzodiazepine receptor site with exceptionally high affinity for Ro 15-4513 in the rat CNS.
Mehta AK; Shank RP
Brain Res; 1995 Dec; 704(2):289-97. PubMed ID: 8788925
[TBL] [Abstract][Full Text] [Related]
20. Anxiolytic cyclopyrrolones zopiclone and suriclone bind to a novel site linked allosterically to benzodiazepine receptors.
Trifiletti RR; Snyder SH
Mol Pharmacol; 1984 Nov; 26(3):458-69. PubMed ID: 6092896
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]