These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

155 related articles for article (PubMed ID: 8386770)

  • 1. (Imidazolylphenyl)pyrrol-2-one inhibitors of cardiac cAMP phosphodiesterase.
    Lampe JW; Chou YL; Hanna RG; Di Meo SV; Erhardt PW; Hagedorn AA; Ingebretsen WR; Cantor E
    J Med Chem; 1993 Apr; 36(8):1041-7. PubMed ID: 8386770
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 4-(4-Guanidinobenzoyl)-2-imidazolones and related compounds: phosphodiesterase inhibitors and novel cardiotonics with combined histamine H2 receptor agonist and PDE III inhibitor activity.
    Glass D; Buschauer A; Tenor H; Bartel S; Will-Shahab L; Krause EG
    Arch Pharm (Weinheim); 1995 Oct; 328(10):709-19. PubMed ID: 8554460
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bemoradan--a novel inhibitor of the rolipram-insensitive cyclic AMP phosphodiesterase from canine heart tissue.
    Moore JB; Combs DW; Tobia AJ
    Biochem Pharmacol; 1991 Jul; 42(3):679-83. PubMed ID: 1650219
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cardiotonic agents. 5. Fragments from the heterocycle-phenyl-imidazole pharmacophore.
    Erhardt PW; Hagedorn AA; Davey D; Pease CA; Venepalli BR; Griffin CW; Gomez RP; Wiggins JR; Ingebretsen WR; Pang D
    J Med Chem; 1989 Jun; 32(6):1173-6. PubMed ID: 2542552
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cardiotonic agents. 7. Inhibition of separated forms of cyclic nucleotide phosphodiesterase from guinea pig cardiac muscle by 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones and related compounds. Structure-activity relationships and correlation with in vivo positive inotropic activity.
    Sircar I; Weishaar RE; Kobylarz D; Moos WH; Bristol JA
    J Med Chem; 1987 Nov; 30(11):1955-62. PubMed ID: 2822926
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Selective inhibition of cAMP phosphodiesterase III activity by the cardiotonic agent saterinone in guinea pig myocardium.
    Brunkhorst D; von der Leyen H; Meyer W; Schmidt-Schumacher C; Scholz H
    Arzneimittelforschung; 1988 Sep; 38(9):1293-8. PubMed ID: 2852013
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibitors of cyclic AMP phosphodiesterase. 3. Synthesis and biological evaluation of pyrido and imidazolyl analogues of 1,2,3,5-tetrahydro-2-oxoimidazo[2,1-b]quinazoline.
    Venuti MC; Stephenson RA; Alvarez R; Bruno JJ; Strosberg AM
    J Med Chem; 1988 Nov; 31(11):2136-45. PubMed ID: 2846839
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A novel class of cardiotonic agents: synthesis and biological evaluation of 5-substituted 3,6-dihydrothiadiazin-2-ones with cyclic AMP phosphodiesterase inhibiting and myofibrillar calcium sensitizing properties.
    Forest MC; Lahouratate P; Martin M; Nadler G; Quiniou MJ; Zimmermann RG
    J Med Chem; 1992 Jan; 35(1):163-72. PubMed ID: 1310113
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of human cardiac cyclic AMP-phosphodiesterases by R 80122, a new selective cyclic AMP-phosphodiesterase III inhibitor: a comparison with other cardiotonic compounds.
    de Cheffoy de Courcelles D; de Loore K; Freyne E; Janssen PA
    J Pharmacol Exp Ther; 1992 Oct; 263(1):6-14. PubMed ID: 1328613
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phosphodiesterase inhibition in ventricular cardiomyocytes from guinea-pig hearts.
    Bethke T; Meyer W; Schmitz W; Scholz H; Stein B; Thomas K; Wenzlaff H
    Br J Pharmacol; 1992 Sep; 107(1):127-33. PubMed ID: 1384905
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cardiotonic agents. 9. Synthesis and biological evaluation of a series of (E)-4,5-dihydro-6-[2-[4-(1H-imidazol-1-yl)phenyl]ethenyl]-3 (2H)-pyridazinones: a novel class of compounds with positive inotropic, antithrombotic, and vasodilatory activities for the treatment of congestive heart failure.
    Sircar I; Steffen RP; Bobowski G; Burke SE; Newton RS; Weishaar RE; Bristol JA; Evans DB
    J Med Chem; 1989 Feb; 32(2):342-50. PubMed ID: 2536438
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of cyclic adenosine-3',5'-monophosphate phosphodiesterase from vascular smooth muscle by rolipram analogues.
    Marivet MC; Bourguignon JJ; Lugnier C; Mann A; Stoclet JC; Wermuth CG
    J Med Chem; 1989 Jul; 32(7):1450-7. PubMed ID: 2544722
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inotropic agents. Synthesis and structure-activity relationships of new milrinone related cAMP PDE III inhibitors.
    Fossa P; Boggia R; Lo Presti E; Mosti L; Dorigo P; Floreani M
    Farmaco; 1997; 52(8-9):523-30. PubMed ID: 9507660
    [TBL] [Abstract][Full Text] [Related]  

  • 14. N-arylrolipram derivatives as potent and selective PDE4 inhibitors.
    Bacher E; Boer C; Bray-French K; Demnitz FW; Keller TH; Mazzoni L; Müller T; Walker C
    Bioorg Med Chem Lett; 1998 Nov; 8(22):3229-34. PubMed ID: 9873708
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Species-dependent pharmacodynamic effects of the selective low Km cyclic AMP phosphodiesterase III inhibitors WIN 58993 and WIN 62005.
    Dundore RL; Pagani ED; Bode DC; Bacon ER; Singh B; Lesher GY; Buchholz RA; Silver PJ
    J Cardiovasc Pharmacol; 1995 Jan; 25(1):14-21. PubMed ID: 7723343
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Proteolysis of cyclic AMP phosphodiesterase-II attenuates its ability to be inhibited by compounds which exert positive inotropic actions in cardiac tissue.
    Price B; Pyne NJ; Houslay MD
    Biochem Pharmacol; 1987 Dec; 36(23):4047-54. PubMed ID: 2825712
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design and synthesis of conformationally constrained analogues of 4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one (Ro 20-1724) as potent inhibitors of cAMP-specific phosphodiesterase.
    Brackeen MF; Cowan DJ; Stafford JA; Schoenen FJ; Veal JM; Domanico PL; Rose D; Strickland AB; Verghese M; Feldman PL
    J Med Chem; 1995 Nov; 38(24):4848-54. PubMed ID: 7490734
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cardiotonic agents. 2. (Imidazolyl)aroylimidazolones, highly potent and selective positive inotropic agents.
    Hagedorn AA; Erhardt PW; Lumma WC; Wohl RA; Cantor E; Chou YL; Ingebretsen WR; Lampe JW; Pang D; Pease CA
    J Med Chem; 1987 Aug; 30(8):1342-7. PubMed ID: 3039132
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The phosphodiesterase 3 inhibitor cilostamide enhances inotropic responses to glucagon but not to dobutamine in rat ventricular myocardium.
    Juan-Fita MJ; Vargas ML; Hernández J
    Eur J Pharmacol; 2005 Apr; 512(2-3):207-13. PubMed ID: 15840406
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Introduction of a conformational switching element on a pyrrolidine ring. Synthesis and evaluation of (R*,R*)-(+/-)-methyl 3-acetyl-4-[3- (cyclopentyloxy)-4-methoxyphenyl]-3-methyl-1-pyrrolidinecarboxylate, a potent and selective inhibitor of cAMP-specific phosphodiesterase.
    Stafford JA; Veal JM; Feldman PL; Valvano NL; Baer PG; Brackeen MF; Brawley ES; Connolly KM; Domanico PL; Han B
    J Med Chem; 1995 Dec; 38(26):4972-5. PubMed ID: 8544172
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 8.