These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1203 related articles for article (PubMed ID: 8387598)

  • 1. Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin.
    Kuo SC; Lee HZ; Juang JP; Lin YT; Wu TS; Chang JJ; Lednicer D; Paull KD; Lin CM; Hamel E
    J Med Chem; 1993 Apr; 36(9):1146-56. PubMed ID: 8387598
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Antitumor agents. 155. Synthesis and biological evaluation of 3',6,7-substituted 2-phenyl-4-quinolones as antimicrotubule agents.
    Li L; Wang HK; Kuo SC; Wu TS; Mauger A; Lin CM; Hamel E; Lee KH
    J Med Chem; 1994 Sep; 37(20):3400-7. PubMed ID: 7932568
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Antitumor agents. 174. 2',3',4',5,6,7-Substituted 2-phenyl-1,8-naphthyridin-4-ones: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.
    Chen K; Kuo SC; Hsieh MC; Mauger A; Lin CM; Hamel E; Lee KH
    J Med Chem; 1997 Jul; 40(14):2266-75. PubMed ID: 9216846
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antitumor agents. 150. 2',3',4',5',5,6,7-substituted 2-phenyl-4-quinolones and related compounds: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.
    Li L; Wang HK; Kuo SC; Wu TS; Lednicer D; Lin CM; Hamel E; Lee KH
    J Med Chem; 1994 Apr; 37(8):1126-35. PubMed ID: 8164254
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antitumor agents. 181. Synthesis and biological evaluation of 6,7,2',3',4'-substituted-1,2,3,4-tetrahydro-2-phenyl-4-quinolones as a new class of antimitotic antitumor agents.
    Xia Y; Yang ZY; Xia P; Bastow KF; Tachibana Y; Kuo SC; Hamel E; Hackl T; Lee KH
    J Med Chem; 1998 Mar; 41(7):1155-62. PubMed ID: 9544215
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antitumor Agents. 211. Fluorinated 2-phenyl-4-quinolone derivatives as antimitotic antitumor agents.
    Xia Y; Yang ZY; Xia P; Hackl T; Hamel E; Mauger A; Wu JH; Lee KH
    J Med Chem; 2001 Nov; 44(23):3932-6. PubMed ID: 11689079
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 6-Alkylamino- and 2,3-dihydro-3'-methoxy-2-phenyl-4-quinazolinones and related compounds: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.
    Hour MJ; Huang LJ; Kuo SC; Xia Y; Bastow K; Nakanishi Y; Hamel E; Lee KH
    J Med Chem; 2000 Nov; 43(23):4479-87. PubMed ID: 11087572
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antitumor agents. 178. Synthesis and biological evaluation of substituted 2-aryl-1,8-naphthyridin-4(1H)-ones as antitumor agents that inhibit tubulin polymerization.
    Chen K; Kuo SC; Hsieh MC; Mauger A; Lin CM; Hamel E; Lee KH
    J Med Chem; 1997 Sep; 40(19):3049-56. PubMed ID: 9301667
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antitumor agents. 196. Substituted 2-thienyl-1,8-naphthyridin-4-ones: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.
    Zhang SX; Bastow KF; Tachibana Y; Kuo SC; Hamel E; Mauger A; Narayanan VL; Lee KH
    J Med Chem; 1999 Oct; 42(20):4081-7. PubMed ID: 10514278
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization.
    Cushman M; Nagarathnam D; Gopal D; Chakraborti AK; Lin CM; Hamel E
    J Med Chem; 1991 Aug; 34(8):2579-88. PubMed ID: 1875350
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and evaluation of analogues of (Z)-1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene as potential cytotoxic and antimitotic agents.
    Cushman M; Nagarathnam D; Gopal D; He HM; Lin CM; Hamel E
    J Med Chem; 1992 Jun; 35(12):2293-306. PubMed ID: 1613753
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antitumor agents. 3. Synthesis and biological activity of 4 beta-alkyl derivatives containing hydroxy, amino, and amido groups of 4'-O-demethyl-4-desoxypodophyllotoxin as antitumor agents.
    Terada T; Fujimoto K; Nomura M; Yamashita J; Wierzba K; Yamazaki R; Shibata J; Sugimoto Y; Yamada Y; Kobunai T
    J Med Chem; 1993 Jun; 36(12):1689-99. PubMed ID: 8389875
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Interactions of tubulin with potent natural and synthetic analogs of the antimitotic agent combretastatin: a structure-activity study.
    Lin CM; Singh SB; Chu PS; Dempcy RO; Schmidt JM; Pettit GR; Hamel E
    Mol Pharmacol; 1988 Aug; 34(2):200-8. PubMed ID: 3412321
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of alkoxy-substituted diaryl compounds and correlation of ring separation with inhibition of tubulin polymerization: differential enhancement of inhibitory effects under suboptimal polymerization reaction conditions.
    Getahun Z; Jurd L; Chu PS; Lin CM; Hamel E
    J Med Chem; 1992 Mar; 35(6):1058-67. PubMed ID: 1552500
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 9-Benzylidene-naphtho[2,3-b]thiophen-4-ones as novel antimicrotubule agents-synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Zuse A; Schmidt P; Baasner S; Böhm KJ; Müller K; Gerlach M; Günther EG; Unger E; Prinz H
    J Med Chem; 2006 Dec; 49(26):7816-25. PubMed ID: 17181164
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pyrimido[4,5-c]quinolin-1(2H)-ones as a novel class of antimitotic agents: Synthesis and in vitro cytotoxic activity.
    Metwally K; Pratsinis H; Kletsas D
    Eur J Med Chem; 2007 Mar; 42(3):344-50. PubMed ID: 17141923
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and biological evaluation of quinoline analogues of flavones as potential anticancer agents and tubulin polymerization inhibitors.
    Shobeiri N; Rashedi M; Mosaffa F; Zarghi A; Ghandadi M; Ghasemi A; Ghodsi R
    Eur J Med Chem; 2016 May; 114():14-23. PubMed ID: 26974371
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Antitumor agents. 141. Synthesis and biological evaluation of novel thiocolchicine analogs: N-acyl-, N-aroyl-, and N-(substituted benzyl)deacetylthiocolchicines as potent cytotoxic and antimitotic compounds.
    Sun L; Hamel E; Lin CM; Hastie SB; Pyluck A; Lee KH
    J Med Chem; 1993 May; 36(10):1474-9. PubMed ID: 8496915
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological evaluation of podophyllotoxin congeners as tubulin polymerization inhibitors.
    Kamal A; Srinivasa Reddy T; Polepalli S; Shalini N; Reddy VG; Subba Rao AV; Jain N; Shankaraiah N
    Bioorg Med Chem; 2014 Oct; 22(19):5466-75. PubMed ID: 25131956
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, anticancer activity and molecular docking studies on a series of heterocyclic trans-cyanocombretastatin analogues as antitubulin agents.
    Penthala NR; Zong H; Ketkar A; Madadi NR; Janganati V; Eoff RL; Guzman ML; Crooks PA
    Eur J Med Chem; 2015 Mar; 92():212-20. PubMed ID: 25557492
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 61.