These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

249 related articles for article (PubMed ID: 8388392)

  • 1. Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2.
    Zheng CF; Guan KL
    J Biol Chem; 1993 May; 268(15):11435-9. PubMed ID: 8388392
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Properties of MEKs, the kinases that phosphorylate and activate the extracellular signal-regulated kinases.
    Zheng CF; Guan KL
    J Biol Chem; 1993 Nov; 268(32):23933-9. PubMed ID: 8226933
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of ERK1 activation site mutants and the effect on recognition by MEK1 and MEK2.
    Butch ER; Guan KL
    J Biol Chem; 1996 Feb; 271(8):4230-5. PubMed ID: 8626767
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential regulation of mitogen-activated protein/ERK kinase (MEK)1 and MEK2 and activation by a Ras-independent mechanism.
    Xu S; Khoo S; Dang A; Witt S; Do V; Zhen E; Schaefer EM; Cobb MH
    Mol Endocrinol; 1997 Oct; 11(11):1618-25. PubMed ID: 9328344
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of recombinant MEK1 and MEK2b expressed in Escherichia coli.
    Russell M; Lange-Carter CA; Johnson GL
    Biochemistry; 1995 May; 34(20):6611-5. PubMed ID: 7756292
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MEKK1 phosphorylates MEK1 and MEK2 but does not cause activation of mitogen-activated protein kinase.
    Xu S; Robbins D; Frost J; Dang A; Lange-Carter C; Cobb MH
    Proc Natl Acad Sci U S A; 1995 Jul; 92(15):6808-12. PubMed ID: 7624324
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MEK2 is a kinase related to MEK1 and is differentially expressed in murine tissues.
    Brott BK; Alessandrini A; Largaespada DA; Copeland NG; Jenkins NA; Crews CM; Erikson RL
    Cell Growth Differ; 1993 Nov; 4(11):921-9. PubMed ID: 8297798
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A proline-rich sequence unique to MEK1 and MEK2 is required for raf binding and regulates MEK function.
    Catling AD; Schaeffer HJ; Reuter CW; Reddy GR; Weber MJ
    Mol Cell Biol; 1995 Oct; 15(10):5214-25. PubMed ID: 7565670
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Isolation of MEK5 and differential expression of alternatively spliced forms.
    English JM; Vanderbilt CA; Xu S; Marcus S; Cobb MH
    J Biol Chem; 1995 Dec; 270(48):28897-902. PubMed ID: 7499418
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Docking sites on mitogen-activated protein kinase (MAPK) kinases, MAPK phosphatases and the Elk-1 transcription factor compete for MAPK binding and are crucial for enzymic activity.
    Bardwell AJ; Abdollahi M; Bardwell L
    Biochem J; 2003 Mar; 370(Pt 3):1077-85. PubMed ID: 12529172
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selective activation of MEK1 but not MEK2 by A-Raf from epidermal growth factor-stimulated Hela cells.
    Wu X; Noh SJ; Zhou G; Dixon JE; Guan KL
    J Biol Chem; 1996 Feb; 271(6):3265-71. PubMed ID: 8621729
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Components of a new human protein kinase signal transduction pathway.
    Zhou G; Bao ZQ; Dixon JE
    J Biol Chem; 1995 May; 270(21):12665-9. PubMed ID: 7759517
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cloning and characterization of cDNAs encoding chicken mitogen-activated protein kinase kinase type 2, MEK2: downregulation of MEK2 in response to inhibition of mitochondrial DNA expression.
    Wang H; Meury L; Morais R
    Biochemistry; 1997 Dec; 36(49):15371-80. PubMed ID: 9398267
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Reconstitution of mitogen-activated protein kinase phosphorylation cascades in bacteria. Efficient synthesis of active protein kinases.
    Khokhlatchev A; Xu S; English J; Wu P; Schaefer E; Cobb MH
    J Biol Chem; 1997 Apr; 272(17):11057-62. PubMed ID: 9110999
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms.
    DĂ©rijard B; Raingeaud J; Barrett T; Wu IH; Han J; Ulevitch RJ; Davis RJ
    Science; 1995 Feb; 267(5198):682-5. PubMed ID: 7839144
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Preferential involvement of MEK1 in the tumor necrosis factor-alpha-induced activation of p42mapk/erk2 in mouse macrophages.
    Winston BW; Remigio LK; Riches DW
    J Biol Chem; 1995 Nov; 270(46):27391-4. PubMed ID: 7499190
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Direct activation of the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by an inducible mitogen-activated protein Kinase/ERK kinase kinase 3 (MEKK) derivative.
    Ellinger-Ziegelbauer H; Brown K; Kelly K; Siebenlist U
    J Biol Chem; 1997 Jan; 272(5):2668-74. PubMed ID: 9006902
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel members of the mitogen-activated protein kinase activator family in Xenopus laevis.
    Yashar BM; Kelley C; Yee K; Errede B; Zon LI
    Mol Cell Biol; 1993 Sep; 13(9):5738-48. PubMed ID: 8395011
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification and characterization of a new mammalian mitogen-activated protein kinase kinase, MKK2.
    Wu J; Harrison JK; Dent P; Lynch KR; Weber MJ; Sturgill TW
    Mol Cell Biol; 1993 Aug; 13(8):4539-48. PubMed ID: 8393135
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of the structure and function of a novel MAP kinase kinase (MKK6).
    Han J; Lee JD; Jiang Y; Li Z; Feng L; Ulevitch RJ
    J Biol Chem; 1996 Feb; 271(6):2886-91. PubMed ID: 8621675
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.