These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

199 related articles for article (PubMed ID: 8393577)

  • 1. Crystal structures of native and inhibited forms of human cathepsin D: implications for lysosomal targeting and drug design.
    Baldwin ET; Bhat TN; Gulnik S; Hosur MV; Sowder RC; Cachau RE; Collins J; Silva AM; Erickson JW
    Proc Natl Acad Sci U S A; 1993 Jul; 90(14):6796-800. PubMed ID: 8393577
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Replacement of isobutyl by trifluoromethyl in pepstatin A selectively affects inhibition of aspartic proteinases.
    Binkert C; Frigerio M; Jones A; Meyer S; Pesenti C; Prade L; Viani F; Zanda M
    Chembiochem; 2006 Jan; 7(1):181-6. PubMed ID: 16307463
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Comparisons of the three-dimensional structures, specificities and glycosylation of renins, yeast proteinase A and cathepsin D.
    Aguilar CF; Dhanaraj V; Guruprasad K; Dealwis C; Badasso M; Cooper JB; Wood SP; Blundell TL
    Adv Exp Med Biol; 1995; 362():155-66. PubMed ID: 8540315
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of UDP-N-acetylglucosamine-phosphotransferase-binding sites on the lysosomal proteases, cathepsins A, B, and D.
    Lukong KE; Elsliger MA; Mort JS; Potier M; Pshezhetsky AV
    Biochemistry; 1999 Jan; 38(1):73-80. PubMed ID: 9890884
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Two crystal structures for cathepsin D: the lysosomal targeting signal and active site.
    Metcalf P; Fusek M
    EMBO J; 1993 Apr; 12(4):1293-302. PubMed ID: 8467789
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphorylation of Asn-linked oligosaccharides located at novel sites on the lysosomal enzyme cathepsin D.
    Cantor AB; Kornfeld S
    J Biol Chem; 1992 Nov; 267(32):23357-63. PubMed ID: 1331083
    [TBL] [Abstract][Full Text] [Related]  

  • 7. X-ray-crystallographic studies of complexes of pepstatin A and a statine-containing human renin inhibitor with endothiapepsin.
    Bailey D; Cooper JB; Veerapandian B; Blundell TL; Atrash B; Jones DM; Szelke M
    Biochem J; 1993 Jan; 289 ( Pt 2)(Pt 2):363-71. PubMed ID: 8424781
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dissection of the pH dependence of inhibitor binding energetics for an aspartic protease: direct measurement of the protonation states of the catalytic aspartic acid residues.
    Xie D; Gulnik S; Collins L; Gustchina E; Suvorov L; Erickson JW
    Biochemistry; 1997 Dec; 36(51):16166-72. PubMed ID: 9405050
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lysine-based structure responsible for selective mannose phosphorylation of cathepsin D and cathepsin L defines a common structural motif for lysosomal enzyme targeting.
    Cuozzo JW; Tao K; Cygler M; Mort JS; Sahagian GG
    J Biol Chem; 1998 Aug; 273(33):21067-76. PubMed ID: 9694859
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The three-dimensional structure at 2.4 A resolution of glycosylated proteinase A from the lysosome-like vacuole of Saccharomyces cerevisiae.
    Aguilar CF; Cronin NB; Badasso M; Dreyer T; Newman MP; Cooper JB; Hoover DJ; Wood SP; Johnson MS; Blundell TL
    J Mol Biol; 1997 Apr; 267(4):899-915. PubMed ID: 9135120
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structures of complexes of rhizopuspepsin with pepstatin and other statine-containing inhibitors.
    Suguna K; Padlan EA; Bott R; Boger J; Parris KD; Davies DR
    Proteins; 1992 Jul; 13(3):195-205. PubMed ID: 1603809
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [Selective inhibitors of plasmepsin II from Plasmodium falciparum based on pepstatin].
    Rumsh LD; Mikhaĭlova AG; Mikhura IV; Prudchenko IA; Chikin LD; Mikhaleva II; Kaliberda EN; Dergousova NI; Mel'nikov EE; Formanovskiĭ AA
    Bioorg Khim; 2008; 34(6):739-46. PubMed ID: 19088746
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure-based subsite specificity mapping of human cathepsin D using statine-based inhibitors.
    Majer P; Collins JR; Gulnik SV; Erickson JW
    Protein Sci; 1997 Jul; 6(7):1458-66. PubMed ID: 9232647
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Crystal structures of Aspergillus oryzae aspartic proteinase and its complex with an inhibitor pepstatin at 1.9A resolution.
    Kamitori S; Ohtaki A; Ino H; Takeuchi M
    J Mol Biol; 2003 Mar; 326(5):1503-11. PubMed ID: 12595261
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Biomimetic Macrocyclic Inhibitors of Human Cathepsin D: Structure-Activity Relationship and Binding Mode Analysis.
    Houštecká R; Hadzima M; Fanfrlík J; Brynda J; Pallová L; Hánová I; Mertlíková-Kaiserová H; Lepšík M; Horn M; Smrčina M; Majer P; Mareš M
    J Med Chem; 2020 Feb; 63(4):1576-1596. PubMed ID: 32003991
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Crystallization and initial crystallographic results for pepstatin A inhibited bovine cathepsin D.
    Bieber F; Brachvogel V; Arni R; Fusek M; Metcalf P
    J Mol Biol; 1992 Oct; 227(4):1265-8. PubMed ID: 1433300
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lysosomal enzyme phosphorylation. II. Protein recognition determinants in either lobe of procathepsin D are sufficient for phosphorylation of both the amino and carboxyl lobe oligosaccharides.
    Cantor AB; Baranski TJ; Kornfeld S
    J Biol Chem; 1992 Nov; 267(32):23349-56. PubMed ID: 1331082
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Redesign of the substrate specificity of human cathepsin D: the dominant role of position 287 in the S2 subsite.
    Scarborough PE; Dunn BM
    Protein Eng; 1994 Apr; 7(4):495-502. PubMed ID: 7913221
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural analysis of plasmepsin II. A comparison with human aspartic proteases.
    Silva AM; Lee AY; Erickson JW; Goldberg DE
    Adv Exp Med Biol; 1998; 436():363-73. PubMed ID: 9561243
    [No Abstract]   [Full Text] [Related]  

  • 20. Structure of human cathepsin D: comparison of inhibitor binding and subdomain displacement with other aspartic proteases.
    Erickson JW; Baldwin ET; Bhat TN; Gulnik S
    Adv Exp Med Biol; 1995; 362():181-92. PubMed ID: 8540317
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 10.