BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

72 related articles for article (PubMed ID: 8394598)

  • 1. Oxadiazolylimidazobenzodiazepines as novel partial agonists with the benzodiazepine receptor: a QSAR analysis.
    Sharma RC; Singh P; Ojha TN
    Res Commun Chem Pathol Pharmacol; 1993 Jun; 80(3):357-62. PubMed ID: 8394598
    [No Abstract]   [Full Text] [Related]  

  • 2. Design and synthesis of new 2-substituted-5-(2-benzylthiophenyl)-1,3,4-oxadiazoles as benzodiazepine receptor agonists.
    Zarghi A; Faizi M; Shafaghi B; Ahadian A; Khojastehpoor HR; Zanganeh V; Tabatabai SA; Shafiee A
    Bioorg Med Chem Lett; 2005 Jun; 15(12):3126-9. PubMed ID: 15876530
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Quantitative structure-activity relationship studies on benzodiazepine receptor binding: investigation of interaction model.
    Gupta SP; Mulchandani V
    Indian J Biochem Biophys; 1993 Jun; 30(3):181-6. PubMed ID: 8406550
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Predictive models for GABAA/benzodiazepine receptor subtypes: studies of quantitative structure-activity relationships for imidazobenzodiazepines at five recombinant GABAA/benzodiazepine receptor subtypes [alphaxbeta3gamma2 (x = 1-3, 5, and 6)] via comparative molecular field analysis.
    Huang Q; Liu R; Zhang P; He X; McKernan R; Gan T; Bennett DW; Cook JM
    J Med Chem; 1998 Oct; 41(21):4130-42. PubMed ID: 9767648
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Quantitative structure-activity relationship studies on benzodiazepine receptor binding: recognition of active sites in receptor and modelling of interaction.
    Gupta SP; Saha RN; Mulchandani V
    J Mol Recognit; 1992 Jun; 5(2):75-80. PubMed ID: 1335277
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The nature of 1,4-benzodiazepines/receptor interactions.
    Borea PA; Gilli G
    Arzneimittelforschung; 1984; 34(6):649-52. PubMed ID: 6091702
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Genetic neural networks for quantitative structure-activity relationships: improvements and application of benzodiazepine affinity for benzodiazepine/GABAA receptors.
    So SS; Karplus M
    J Med Chem; 1996 Dec; 39(26):5246-56. PubMed ID: 8978853
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel benzodiazepine receptor partial agonists: oxadiazolylimidazobenzodiazepines.
    Watjen F; Baker R; Engelstoff M; Herbert R; MacLeod A; Knight A; Merchant K; Moseley J; Saunders J; Swain CJ
    J Med Chem; 1989 Oct; 32(10):2282-91. PubMed ID: 2552115
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Imidazo[1,2-a]pyrimidines as functionally selective GABA(A) ligands.
    Blackaby WP; Atack JR; Bromidge F; Castro JL; Goodacre SC; Hallett DJ; Lewis RT; Marshall GR; Pike A; Smith AJ; Street LJ; Tattersall DF; Wafford KA
    Bioorg Med Chem Lett; 2006 Mar; 16(5):1175-9. PubMed ID: 16406613
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 3D-pharmacophores of flavonoid binding at the benzodiazepine GABA(A) receptor site using 4D-QSAR analysis.
    Hong X; Hopfinger AJ
    J Chem Inf Comput Sci; 2003; 43(1):324-36. PubMed ID: 12546568
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 2-(oxadiazolyl)- and 2-(thiazolyl)imidazo[1,2-a]pyrimidines as agonists and inverse agonists at benzodiazepine receptors.
    Tully WR; Gardner CR; Gillespie RJ; Westwood R
    J Med Chem; 1991 Jul; 34(7):2060-7. PubMed ID: 1648620
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Exploring selectivity requirements for peripheral versus central benzodiazepine receptor binding affinity: QSAR modeling of 2-phenylimidazo[1,2-a]pyridine acetamides using topological and physicochemical descriptors.
    Dalai MK; Leonard JT; Roy K
    Indian J Biochem Biophys; 2006 Apr; 43(2):105-18. PubMed ID: 16955759
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Conformational changes at benzodiazepine binding sites of GABA(A) receptors detected with a novel technique.
    Berezhnoy D; Baur R; Gonthier A; Foucaud B; Goeldner M; Sigel E
    J Neurochem; 2005 Feb; 92(4):859-66. PubMed ID: 15686488
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Axial chirality and affinity at the GABA(A) receptor of pyrimido[1,2-a][1,4]benzodiazepines and related compounds.
    Lee S; Kamide T; Tabata H; Takahashi H; Shiro M; Natsugari H
    Bioorg Med Chem; 2008 Nov; 16(21):9519-23. PubMed ID: 18829330
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The use of a pharmacophore model for identification of novel ligands for the benzodiazepine binding site of the GABAA receptor.
    Kahnberg P; Howard MH; Liljefors T; Nielsen M; Nielsen EØ; Sterner O; Pettersson I
    J Mol Graph Model; 2004 Dec; 23(3):253-61. PubMed ID: 15530821
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Affinity of 3-acyl substituted 4-quinolones at the benzodiazepine site of GABA(A) receptors.
    Lager E; Nilsson J; Østergaard Nielsen E; Nielsen M; Liljefors T; Sterner O
    Bioorg Med Chem; 2008 Jul; 16(14):6936-48. PubMed ID: 18541432
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 2,5-Dihydropyrazolo[4,3-c]pyridin-3-ones: functionally selective benzodiazepine binding site ligands on the GABAA receptor.
    Mitchinson A; Atack JR; Blurton P; Carling RW; Castro JL; Curley KS; Russell MG; Marshall G; McKernan RM; Moore KW; Narquizian R; Smith A; Street LJ; Thompson SA; Wafford K
    Bioorg Med Chem Lett; 2004 Jul; 14(13):3441-4. PubMed ID: 15177449
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Conformational shifts at the benzodiazepine receptor related to the binding of agonists antagonists and inverse agonists.
    Fryer RI; Cook C; Gilman NW; Walser A
    Life Sci; 1986 Nov; 39(21):1947-57. PubMed ID: 3023774
    [No Abstract]   [Full Text] [Related]  

  • 19. Down-regulation of benzodiazepine binding to alpha 5 subunit-containing gamma-aminobutyric Acid(A) receptors in tolerant rat brain indicates particular involvement of the hippocampal CA1 region.
    Li M; Szabo A; Rosenberg HC
    J Pharmacol Exp Ther; 2000 Nov; 295(2):689-96. PubMed ID: 11046107
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Relative positioning of diazepam in the benzodiazepine-binding-pocket of GABA receptors.
    Tan KR; Baur R; Charon S; Goeldner M; Sigel E
    J Neurochem; 2009 Dec; 111(5):1264-73. PubMed ID: 19804380
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.