These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

233 related articles for article (PubMed ID: 8394989)

  • 1. G protein amino-terminal alpha i2/alpha s chimeras reveal amino acids important in regulating alpha s activity.
    Russell M; Johnson GL
    Mol Pharmacol; 1993 Aug; 44(2):255-63. PubMed ID: 8394989
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activating mutations in the NH2- and COOH-terminal moieties of the Gs alpha subunit have dominant phenotypes and distinguishable kinetics of adenylyl cyclase stimulation.
    Gupta SK; Dhanasekaran N; Heasley LE; Johnson GL
    J Cell Biochem; 1991 Dec; 47(4):359-68. PubMed ID: 1665495
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The NH2-terminal alpha subunit attenuator domain confers regulation of G protein activation by beta gamma complexes.
    Dhanasekaran N; Osawa S; Johnson GL
    J Cell Biochem; 1991 Dec; 47(4):352-8. PubMed ID: 1795017
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutant alpha subunits of Gi2 inhibit cyclic AMP accumulation.
    Wong YH; Federman A; Pace AM; Zachary I; Evans T; Pouysségur J; Bourne HR
    Nature; 1991 May; 351(6321):63-5. PubMed ID: 1851251
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Substitution of three amino acids switches receptor specificity of Gq alpha to that of Gi alpha.
    Conklin BR; Farfel Z; Lustig KD; Julius D; Bourne HR
    Nature; 1993 May; 363(6426):274-6. PubMed ID: 8387644
    [TBL] [Abstract][Full Text] [Related]  

  • 6. S111N mutation in the helical domain of human Gs(alpha) reduces its GDP/GTP exchange rate.
    Brito M; Guzmán L; Romo X; Soto X; Hinrichs MV; Olate J
    J Cell Biochem; 2002; 85(3):615-20. PubMed ID: 11968001
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Genetic and structural analysis of G protein alpha subunit regulatory domains.
    Johnson GL; Dhanasekaran N; Gupta SK; Lowndes JM; Vaillancourt RR; Ruoho AE
    J Cell Biochem; 1991 Oct; 47(2):136-46. PubMed ID: 1661737
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hydrolysis of GTP by the alpha-chain of Gs and other GTP binding proteins.
    Bourne HR; Landis CA; Masters SB
    Proteins; 1989; 6(3):222-30. PubMed ID: 2516316
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutagenesis in the switch IV of the helical domain of the human Gsalpha reduces its GDP/GTP exchange rate.
    Echeverría V; Hinrichs MV; Torrejón M; Ropero S; Martinez J; Toro MJ; Olate J
    J Cell Biochem; 2000 Jan; 76(3):368-75. PubMed ID: 10649434
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rapid GDP release from Gs alpha in patients with gain and loss of endocrine function.
    Iiri T; Herzmark P; Nakamoto JM; van Dop C; Bourne HR
    Nature; 1994 Sep; 371(6493):164-8. PubMed ID: 8072545
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A surface-exposed region of G(salpha) in which substitutions decrease receptor-mediated activation and increase receptor affinity.
    Grishina G; Berlot CH
    Mol Pharmacol; 2000 Jun; 57(6):1081-92. PubMed ID: 10825378
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Carboxyl-terminal mutations of Gq alpha and Gs alpha that alter the fidelity of receptor activation.
    Conklin BR; Herzmark P; Ishida S; Voyno-Yasenetskaya TA; Sun Y; Farfel Z; Bourne HR
    Mol Pharmacol; 1996 Oct; 50(4):885-90. PubMed ID: 8863834
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Localization of segments in the Gs protein interacting with adenylate cyclase using a Gs/G0-chimera].
    Lipkin VM; Krasovskaia LA; Muranov AV; Pronin AN; Udovichenko IP; Iurovskaia AA; Zagranichnyĭ VE
    Bioorg Khim; 1993 Dec; 19(12):1191-204. PubMed ID: 8117336
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Gi alpha 1 selectively couples somatostatin receptor subtype 3 to adenylyl cyclase: identification of the functional domains of this alpha subunit necessary for mediating the inhibition by somatostatin of cAMP formation.
    Law SF; Zaina S; Sweet R; Yasuda K; Bell GI; Stadel J; Reisine T
    Mol Pharmacol; 1994 Apr; 45(4):587-90. PubMed ID: 8183236
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The core domain of the tissue transglutaminase Gh hydrolyzes GTP and ATP.
    Iismaa SE; Chung L; Wu MJ; Teller DC; Yee VC; Graham RM
    Biochemistry; 1997 Sep; 36(39):11655-64. PubMed ID: 9305955
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutagenesis within helix 6 of the human beta1-adrenergic receptor identifies Lysine324 as a residue involved in imparting the high-affinity binding state of agonists.
    Zeitoun O; Santos NM; Gardner LA; White SW; Bahouth SW
    Mol Pharmacol; 2006 Sep; 70(3):838-50. PubMed ID: 16760361
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulation of G protein activation and effector modulation by fusion proteins between the human 5-hydroxytryptamine(1A) receptor and the alpha subunit of G(i1): differences in receptor-constitutive activity imparted by single amino acid substitutions in G(i1)alpha.
    Kellett E; Carr IC; Milligan G
    Mol Pharmacol; 1999 Oct; 56(4):684-92. PubMed ID: 10496950
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interactions between the amino- and carboxyl-terminal regions of G alpha subunits: analysis of mutated G alpha o/G alpha i2 chimeras.
    Denker BM; Boutin PM; Neer EJ
    Biochemistry; 1995 Apr; 34(16):5544-53. PubMed ID: 7727415
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A new constitutively activating mutation of the Gs protein alpha subunit-gsp oncogene is found in human pituitary tumours.
    Clementi E; Malgaretti N; Meldolesi J; Taramelli R
    Oncogene; 1990 Jul; 5(7):1059-61. PubMed ID: 2115641
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Guanine nucleotide exchange-independent activation of Gs protein by beta2-adrenoceptor.
    Ugur O; Oner SS; Molinari P; Ambrosio C; Sayar K; Onaran HO
    Mol Pharmacol; 2005 Sep; 68(3):720-8. PubMed ID: 15933218
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.