These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

111 related articles for article (PubMed ID: 8408069)

  • 1. Identification of regions in interleukin-1 alpha important for activity.
    Gayle RB; Poindexter K; Cosman D; Dower SK; Gillis S; Hopp T; Jerzy R; Kronheim S; Lum V; Lewis A
    J Biol Chem; 1993 Oct; 268(29):22105-11. PubMed ID: 8408069
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mapping receptor binding sites in interleukin (IL)-1 receptor antagonist and IL-1 beta by site-directed mutagenesis. Identification of a single site in IL-1ra and two sites in IL-1 beta.
    Evans RJ; Bray J; Childs JD; Vigers GP; Brandhuber BJ; Skalicky JJ; Thompson RC; Eisenberg SP
    J Biol Chem; 1995 May; 270(19):11477-83. PubMed ID: 7744786
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of the discontinuous binding site in human interleukin 1 beta for the type I interleukin 1 receptor.
    Labriola-Tompkins E; Chandran C; Kaffka KL; Biondi D; Graves BJ; Hatada M; Madison VS; Karas J; Kilian PL; Ju G
    Proc Natl Acad Sci U S A; 1991 Dec; 88(24):11182-6. PubMed ID: 1837145
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mapping of neutralizing epitopes and the receptor binding site of human interleukin 1 beta.
    Simon PL; Kumar V; Lillquist JS; Bhatnagar P; Einstein R; Lee J; Porter T; Green D; Sathe G; Young PR
    J Biol Chem; 1993 May; 268(13):9771-9. PubMed ID: 7683661
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A single amino acid difference between human and monkey interleukin (IL)-1beta dictates effective binding to soluble type II IL-1 receptor.
    Smith DE; Ketchem RR; Moore H; Anderson Z; Renshaw BR; Friend DJ; Sims JE
    J Biol Chem; 2002 Dec; 277(49):47619-25. PubMed ID: 12356774
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Loop substitution as a tool to identify active sites of interleukin-1 beta.
    Palla E; Bensi G; Solito E; Buonamassa DT; Fassina G; Raugei G; Spano F; Galeotti C; Mora M; Domenighini M
    J Biol Chem; 1993 Jun; 268(18):13486-92. PubMed ID: 7685764
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Deletion mutants of human interleukin 1 beta with significantly reduced agonist properties: search for the agonist/antagonist switch in ligands to the interleukin 1 receptors.
    Simoncsits A; Bristulf J; Tjörnhammar ML; Cserzö M; Pongor S; Rybakina E; Gatti S; Bartfai T
    Cytokine; 1994 Mar; 6(2):206-14. PubMed ID: 8032002
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mapping of receptor binding sites on IL-1 beta by reconstruction of IL-1ra-like domains.
    Boraschi D; Bossù P; Ruggiero P; Tagliabue A; Bertini R; Macchia G; Gasbarro C; Pellegrini L; Melillo G; Ulisse E; Visconti U; Bizzarri C; Del Grosso E; Mackay AR; Frascotti G; Frigerio F; Grifantini R; Grandi G
    J Immunol; 1995 Nov; 155(10):4719-25. PubMed ID: 7594472
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Construction of interleukin-1 alpha mutants using unequal contamination of synthetic oligonucleotides.
    Poindexter K; Jerzy R; Gayle RB
    Nucleic Acids Res; 1991 Apr; 19(8):1899-904. PubMed ID: 1840657
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of critical regions within the TIR domain of IL-1 receptor type I.
    Radons J; Falk W; Dove S
    Int J Biochem Cell Biol; 2015 Nov; 68():15-20. PubMed ID: 26279140
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A mutational analysis of receptor binding sites of interleukin-1 beta: differences in binding of human interleukin-1 beta muteins to human and mouse receptors.
    Grütter MG; van Oostrum J; Priestle JP; Edelmann E; Joss U; Feige U; Vosbeck K; Schmitz A
    Protein Eng; 1994 May; 7(5):663-71. PubMed ID: 8073036
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Multiple amino acid substitutions suggest a structural basis for the separation of biological activity and receptor binding in a mutant interleukin-1 beta protein.
    Auron PE; Quigley GJ; Rosenwasser LJ; Gehrke L
    Biochemistry; 1992 Jul; 31(29):6632-8. PubMed ID: 1386253
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Permuteins of interleukin 1 beta--a simplified approach for the construction of permutated proteins having new termini.
    Horlick RA; George HJ; Cooke GM; Tritch RJ; Newton RC; Dwivedi A; Lischwe M; Salemme FR; Weber PC; Horuk R
    Protein Eng; 1992 Jul; 5(5):427-31. PubMed ID: 1518791
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Crystal structure of the type-I interleukin-1 receptor complexed with interleukin-1beta.
    Vigers GP; Anderson LJ; Caffes P; Brandhuber BJ
    Nature; 1997 Mar; 386(6621):190-4. PubMed ID: 9062193
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CLoning of equine interleukin 1 alpha and equine interleukin 1 beta and determination of their full-length cDNA sequences.
    Howard RD; McIlwraith CW; Trotter GW; Nyborg JK
    Am J Vet Res; 1998 Jun; 59(6):704-11. PubMed ID: 9622738
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure-function mapping of interleukin 1 precursors. Cleavage leads to a conformational change in the mature protein.
    Hazuda DJ; Strickler J; Simon P; Young PR
    J Biol Chem; 1991 Apr; 266(11):7081-6. PubMed ID: 2016316
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutational analysis of the thermostable arginine repressor from Bacillus stearothermophilus: dissecting residues involved in DNA binding properties.
    Karaivanova IM; Weigel P; Takahashi M; Fort C; Versavaud A; Van Duyne G; Charlier D; Hallet JN; Glansdorff N; Sakanyan V
    J Mol Biol; 1999 Aug; 291(4):843-55. PubMed ID: 10452892
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Amino acids conserved in interleukin-1 receptors (IL-1Rs) and the Drosophila toll protein are essential for IL-1R signal transduction.
    Heguy A; Baldari CT; Macchia G; Telford JL; Melli M
    J Biol Chem; 1992 Feb; 267(4):2605-9. PubMed ID: 1531143
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-function analysis of human IL-1 alpha: identification of residues required for binding to the human type I IL-1 receptor.
    Labriola-Tompkins E; Chandran C; Varnell TA; Madison VS; Ju G
    Protein Eng; 1993 Jul; 6(5):535-9. PubMed ID: 7692435
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Single amino acid substitutions and deletions that alter the G protein coupling properties of the V2 vasopressin receptor identified in yeast by receptor random mutagenesis.
    Erlenbach I; Kostenis E; Schmidt C; Serradeil-Le Gal C; Raufaste D; Dumont ME; Pausch MH; Wess J
    J Biol Chem; 2001 Aug; 276(31):29382-92. PubMed ID: 11375990
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.