These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

148 related articles for article (PubMed ID: 8408475)

  • 1. Thyroid hormone resistance syndrome: correlation of dominant negative activity and location of mutations.
    Nagaya T; Eberhardt NL; Jameson JL
    J Clin Endocrinol Metab; 1993 Oct; 77(4):982-90. PubMed ID: 8408475
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Variable transcriptional activity and ligand binding of mutant beta 1 3,5,3'-triiodothyronine receptors from four families with generalized resistance to thyroid hormone.
    Meier CA; Dickstein BM; Ashizawa K; McClaskey JH; Muchmore P; Ransom SC; Menke JB; Hao EH; Usala SJ; Bercu BB
    Mol Endocrinol; 1992 Feb; 6(2):248-58. PubMed ID: 1569968
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Thyroid hormone receptor-beta mutants associated with generalized resistance to thyroid hormone show defects in their ligand-sensitive repression function.
    Piedrafita FJ; Ortiz MA; Pfahl M
    Mol Endocrinol; 1995 Nov; 9(11):1533-48. PubMed ID: 8584031
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dominant negative and DNA-binding properties of mutant thyroid hormone receptors that are defective in homodimerization but not heterodimerization.
    Kitajima K; Nagaya T; Jameson JL
    Thyroid; 1995 Oct; 5(5):343-53. PubMed ID: 8563470
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dominant negative inhibition by mutant thyroid hormone receptors is thyroid hormone response element and receptor isoform specific.
    Zavacki AM; Harney JW; Brent GA; Larsen PR
    Mol Endocrinol; 1993 Oct; 7(10):1319-30. PubMed ID: 8264663
    [TBL] [Abstract][Full Text] [Related]  

  • 6. N-terminal variants of thyroid hormone receptor beta: differential function and potential contribution to syndrome of resistance to thyroid hormone.
    Ng L; Forrest D; Haugen BR; Wood WM; Curran T
    Mol Endocrinol; 1995 Sep; 9(9):1202-13. PubMed ID: 7491112
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Amino acid substitutions of thyroid hormone receptor-beta at codon 435 with resistance to thyroid hormone selectively alter homodimer formation.
    Nomura Y; Nagaya T; Tsukaguchi H; Takamatsu J; Seo H
    Endocrinology; 1996 Oct; 137(10):4082-6. PubMed ID: 8828460
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Thyroid hormone resistance syndrome. Inhibition of normal receptor function by mutant thyroid hormone receptors.
    Chatterjee VK; Nagaya T; Madison LD; Datta S; Rentoumis A; Jameson JL
    J Clin Invest; 1991 Jun; 87(6):1977-84. PubMed ID: 2040690
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interaction of human beta 1 thyroid hormone receptor and its mutants with DNA and retinoid X receptor beta. T3 response element-dependent dominant negative potency.
    Meier CA; Parkison C; Chen A; Ashizawa K; Meier-Heusler SC; Muchmore P; Cheng SY; Weintraub BD
    J Clin Invest; 1993 Oct; 92(4):1986-93. PubMed ID: 8408652
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Thyroid hormone receptor mutants that cause resistance to thyroid hormone. Evidence for receptor competition for DNA sequences in target genes.
    Nagaya T; Madison LD; Jameson JL
    J Biol Chem; 1992 Jun; 267(18):13014-9. PubMed ID: 1618799
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular diagnosis and characterization of thyroid hormone resistance syndromes.
    Usala SJ
    Thyroid; 1991; 1(4):361-7. PubMed ID: 1668726
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nuclear corepressors enhance the dominant negative activity of mutant receptors that cause resistance to thyroid hormone.
    Tagami T; Jameson JL
    Endocrinology; 1998 Feb; 139(2):640-50. PubMed ID: 9449636
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Resistance to thyroid hormone caused by two mutant thyroid hormone receptors beta, R243Q and R243W, with marked impairment of function that cannot be explained by altered in vitro 3,5,3'-triiodothyroinine binding affinity.
    Yagi H; Pohlenz J; Hayashi Y; Sakurai A; Refetoff S
    J Clin Endocrinol Metab; 1997 May; 82(5):1608-14. PubMed ID: 9141558
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Divergent dimerization properties of mutant beta 1 thyroid hormone receptors are associated with different dominant negative activities.
    Hao E; Menke JB; Smith AM; Jones C; Geffner ME; Hershman JM; Wuerth JP; Samuels HH; Ways DK; Usala SJ
    Mol Endocrinol; 1994 Jul; 8(7):841-51. PubMed ID: 7984146
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Thyroid hormone receptor dimerization is required for dominant negative inhibition by mutations that cause thyroid hormone resistance.
    Nagaya T; Jameson JL
    J Biol Chem; 1993 Jul; 268(21):15766-71. PubMed ID: 8340402
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dominant negative transcriptional regulation by a mutant thyroid hormone receptor-beta in a family with generalized resistance to thyroid hormone.
    Sakurai A; Miyamoto T; Refetoff S; DeGroot LJ
    Mol Endocrinol; 1990 Dec; 4(12):1988-94. PubMed ID: 2082193
    [TBL] [Abstract][Full Text] [Related]  

  • 17. New insights on the mechanism(s) of the dominant negative effect of mutant thyroid hormone receptor in generalized resistance to thyroid hormone.
    Yen PM; Sugawara A; Refetoff S; Chin WW
    J Clin Invest; 1992 Nov; 90(5):1825-31. PubMed ID: 1430208
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Triiodothyroacetic acid has unique potential for therapy of resistance to thyroid hormone.
    Takeda T; Suzuki S; Liu RT; DeGroot LJ
    J Clin Endocrinol Metab; 1995 Jul; 80(7):2033-40. PubMed ID: 7608251
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cell type-dependent modulation of the dominant negative action of human mutant thyroid hormone beta 1 receptors.
    Wong R; Zhu XG; Pineda MA; Cheng SY; Weintraub BD
    Mol Med; 1995 Mar; 1(3):306-19. PubMed ID: 8529109
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel natural mutation in the thyroid hormone receptor defines a dual functional domain that exchanges nuclear receptor corepressors and coactivators.
    Tagami T; Gu WX; Peairs PT; West BL; Jameson JL
    Mol Endocrinol; 1998 Dec; 12(12):1888-902. PubMed ID: 9849963
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.