These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

127 related articles for article (PubMed ID: 8410995)

  • 21. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
    Stefański T; Mikstacka R; Kurczab R; Dutkiewicz Z; Kucińska M; Murias M; Zielińska-Przyjemska M; Cichocki M; Teubert A; Kaczmarek M; Hogendorf A; Sobiak S
    Eur J Med Chem; 2018 Jan; 144():797-816. PubMed ID: 29291446
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Antitumor agents. 178. Synthesis and biological evaluation of substituted 2-aryl-1,8-naphthyridin-4(1H)-ones as antitumor agents that inhibit tubulin polymerization.
    Chen K; Kuo SC; Hsieh MC; Mauger A; Lin CM; Hamel E; Lee KH
    J Med Chem; 1997 Sep; 40(19):3049-56. PubMed ID: 9301667
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Antitumor agents. 150. 2',3',4',5',5,6,7-substituted 2-phenyl-4-quinolones and related compounds: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.
    Li L; Wang HK; Kuo SC; Wu TS; Lednicer D; Lin CM; Hamel E; Lee KH
    J Med Chem; 1994 Apr; 37(8):1126-35. PubMed ID: 8164254
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synthesis and biological evaluation of curcumin inspired imidazo[1,2-a]pyridine analogues as tubulin polymerization inhibitors.
    Ramya PVS; Guntuku L; Angapelly S; Digwal CS; Lakshmi UJ; Sigalapalli DK; Babu BN; Naidu VGM; Kamal A
    Eur J Med Chem; 2018 Jan; 143():216-231. PubMed ID: 29174816
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin.
    Kuo SC; Lee HZ; Juang JP; Lin YT; Wu TS; Chang JJ; Lednicer D; Paull KD; Lin CM; Hamel E
    J Med Chem; 1993 Apr; 36(9):1146-56. PubMed ID: 8387598
    [TBL] [Abstract][Full Text] [Related]  

  • 26. [4-(imidazol-1-yl)thiazol-2-yl]phenylamines. A novel class of highly potent colchicine site binding tubulin inhibitors: synthesis and cytotoxic activity on selected human cancer cell lines.
    Mahboobi S; Sellmer A; Höcher H; Eichhorn E; Bär T; Schmidt M; Maier T; Stadlwieser JF; Beckers TL
    J Med Chem; 2006 Sep; 49(19):5769-76. PubMed ID: 16970401
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Synthesis, anticancer activity and molecular docking studies on a series of heterocyclic trans-cyanocombretastatin analogues as antitubulin agents.
    Penthala NR; Zong H; Ketkar A; Madadi NR; Janganati V; Eoff RL; Guzman ML; Crooks PA
    Eur J Med Chem; 2015 Mar; 92():212-20. PubMed ID: 25557492
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Antitumor agents. 196. Substituted 2-thienyl-1,8-naphthyridin-4-ones: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.
    Zhang SX; Bastow KF; Tachibana Y; Kuo SC; Hamel E; Mauger A; Narayanan VL; Lee KH
    J Med Chem; 1999 Oct; 42(20):4081-7. PubMed ID: 10514278
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Imidazolone-amide bridges and their effects on tubulin polymerization in cis-locked vinylogous combretastatin-A4 analogues: synthesis and biological evaluation.
    Li YW; Liu J; Liu N; Shi D; Zhou XT; Lv JG; Zhu J; Zheng CH; Zhou YJ
    Bioorg Med Chem; 2011 Jun; 19(11):3579-84. PubMed ID: 21536450
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Synthesis, antiproliferative activity and tubulin targeting effect of acridinone and dioxophenothiazine derivatives.
    Verones V; Flouquet N; Lecoeur M; Lemoine A; Farce A; Baldeyrou B; Mahieu C; Wattez N; Lansiaux A; Goossens JF; Berthelot P; Lebegue N
    Eur J Med Chem; 2013 Jan; 59():39-47. PubMed ID: 23202849
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Design, Synthesis and Antitumor Activity of Novel link-bridge and B-Ring Modified Combretastatin A-4 (CA-4) Analogues as Potent Antitubulin Agents.
    Duan YT; Man RJ; Tang DJ; Yao YF; Tao XX; Yu C; Liang XY; Makawana JA; Zou MJ; Wang ZC; Zhu HL
    Sci Rep; 2016 May; 6():25387. PubMed ID: 27138035
    [TBL] [Abstract][Full Text] [Related]  

  • 32. 2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
    Chang JY; Yang MF; Chang CY; Chen CM; Kuo CC; Liou JP
    J Med Chem; 2006 Oct; 49(21):6412-5. PubMed ID: 17034147
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Interactions of tubulin with potent natural and synthetic analogs of the antimitotic agent combretastatin: a structure-activity study.
    Lin CM; Singh SB; Chu PS; Dempcy RO; Schmidt JM; Pettit GR; Hamel E
    Mol Pharmacol; 1988 Aug; 34(2):200-8. PubMed ID: 3412321
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Synthesis and bioevaluation of N,4-diaryl-1,3-thiazole-2-amines as tubulin inhibitors with potent antiproliferative activity.
    Sun M; Xu Q; Xu J; Wu Y; Wang Y; Zuo D; Guan Q; Bao K; Wang J; Wu Y; Zhang W
    PLoS One; 2017; 12(3):e0174006. PubMed ID: 28333984
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Synthesis and biological evaluation of a series of podophyllotoxins derivatives as a class of potent antitubulin agents.
    Liu Y; Wei D; Zhao Y; Cheng W; Lu Y; Ma Y; Li X; Han C; Wei Y; Cao H; Zhao C
    Bioorg Med Chem; 2012 Nov; 20(21):6285-95. PubMed ID: 23022053
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
    Wang G; Li C; He L; Lei K; Wang F; Pu Y; Yang Z; Cao D; Ma L; Chen J; Sang Y; Liang X; Xiang M; Peng A; Wei Y; Chen L
    Bioorg Med Chem; 2014 Apr; 22(7):2060-79. PubMed ID: 24629450
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Structure-activity analysis of the interaction of curacin A, the potent colchicine site antimitotic agent, with tubulin and effects of analogs on the growth of MCF-7 breast cancer cells.
    Verdier-Pinard P; Lai JY; Yoo HD; Yu J; Marquez B; Nagle DG; Nambu M; White JD; Falck JR; Gerwick WH; Day BW; Hamel E
    Mol Pharmacol; 1998 Jan; 53(1):62-76. PubMed ID: 9443933
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Synthesis, cytotoxic evaluation and molecular docking study of 2-alkylthio-4-(2,3,4-trimethoxyphenyl)-5-aryl-thiazoles as tubulin polymerization inhibitors.
    Salehi M; Amini M; Ostad SN; Riazi GH; Assadieskandar A; Shafiei B; Shafiee A
    Bioorg Med Chem; 2013 Dec; 21(24):7648-54. PubMed ID: 24238904
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Exploring the size adaptability of the B ring binding zone of the colchicine site of tubulin with para-nitrogen substituted isocombretastatins.
    Jiménez C; Ellahioui Y; Álvarez R; Aramburu L; Riesco A; González M; Vicente A; Dahdouh A; Ibn Mansour A; Jiménez C; Martín D; Sarmiento RG; Medarde M; Caballero E; Peláez R
    Eur J Med Chem; 2015 Jul; 100():210-22. PubMed ID: 26092446
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Synthesis and biological evaluation of quinoline analogues of flavones as potential anticancer agents and tubulin polymerization inhibitors.
    Shobeiri N; Rashedi M; Mosaffa F; Zarghi A; Ghandadi M; Ghasemi A; Ghodsi R
    Eur J Med Chem; 2016 May; 114():14-23. PubMed ID: 26974371
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.